Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Clinique Smart Clinical Repair Wrinkle Correcting Cream Versus Paula's Choice Pro-Collagen Multi-Peptide Booster

Clinique Smart Clinical Repair Wrinkle Correcting Cream Versus Paula's Choice Pro-Collagen Multi-Peptide Booster Detailed comparison of Clinique Smart Clinical Repair Wrinkle Correcting Cream versus Paula's Choice Pro-Collagen Multi-Peptide Booster. This anti-

This source-based comparison does not add ratings or recommend a winner.

Clinique Smart Clinical Repair Wrinkle Correcting Cream Versus Paula's Choice Pro-Collagen Multi-Peptide Booster Detailed comparison of Clinique Smart Clinical Repair Wrinkle Correcting Cream versus Paula's Choice Pro-Collagen Multi-Peptide Booster. This anti-aging moisturizer is formulated around Acetyl Hexapeptide-8 and Acetyl Octapeptide-3 to soften the look of wrinkles and refine skin texture. Water Glycerin Isostearyl Neopentanoate Butylene Glycol Glyceryl Stearate PEG-100 Stearate Dimethicone Cetearyl Alcohol Acetyl Hexapeptide-8 Acetyl Octapeptide-3 Aminopropyl Ascorbyl Phosphate Palmitoyl Tetrapeptide-7 Algae Extract Sodium Hyaluronate Palmitoyl Hexapeptide-12 Sigesbeckia Orientalis Extract Whey Protein Dipeptide Diaminobutyroyl Benzylamide Diacetate Acetyl Glucosamine Caffeine Palmitoyl Tripeptide-1 Glycine Soja Seed Extract Cetearyl Glucoside Tocopheryl Acetate Isohexadecane Petrolatum Caprylyl Glycol Glycereth-26 Acrylates/C10-30 Alkyl Acrylate Crosspolymer Tromethamine Glyceryl Polymethacrylate PEG-8 Polysorbate 20 Hexylene Glycol Polysorbate 80 Carbomer Acrylamide/Sodium Acryloyldimethyltaurate Copolymer Sorbitan Oleate Cetyl Alcohol Sodium Citrate Disodium EDTA Phenoxyethanol Potassium Sorbate Sodium Benzoate Water, Glycerin, Isostearyl Neopentanoate, Butylene Glycol, Glyceryl Stearate, PEG-100 Stearate, Dimethicone, Cetearyl Alcohol, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Aminopropyl Ascorbyl Phosphate, Palmitoyl Tetrapeptide-7, Algae Extract, Sodium Hyaluronate, Palmitoyl Hexapeptide-12, Sigesbeckia Orientalis Extract, Whey Protein, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetyl Glucosamine, Caffeine, Palmitoyl Tripeptide-1, Glycine Soja Seed Extract, Cetearyl Glucoside, Tocopheryl Acetate, Isohexadecane, Petrolatum, Caprylyl Glycol, Glycereth-26, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Glyceryl Polymethacrylate, PEG-8, Polysorbate 20, Hexylene Glycol, Polysorbate 80, Carbomer, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Sorbitan Oleate, Cetyl Alcohol, Sodium Citrate, Disodium EDTA, Phenoxyethanol, Potassium Sorbate, Sodium Benzoate Pentylene Glycol Hydrolyzed Yeast Extract Pyrus Malus Fruit Extract Propanediol Ceramide AP 1,2-Hexanediol Glyceryl Glucoside Palmitoyl Tetrapeptide-72 Amide Sh-Polypeptide-121 Tridecapeptide-1 Polyglucuronic Acid C9-12 Alkane Ammonium Polyacryloyldimethyl Taurate Polygonum Bistorta Root Extract Bacillus Ferment Lecithin Sodium Phytate Coco-Caprylate/Caprate Cetyl Hydroxyethylcellulose Xanthan Gum Ethylhexylglycerin Magnesium Chloride Water, Glycerin, Pentylene Glycol, Hydrolyzed Yeast Extract, Pyrus Malus Fruit Extract, Dimethicone, Propanediol, Ceramide AP, 1,2-Hexanediol, Glyceryl Glucoside, Palmitoyl Tetrapeptide-72 Amide, Sh-Polypeptide-121, Tridecapeptide-1, Polyglucuronic Acid, Sodium Hyaluronate, C9-12 Alkane, Ammonium Polyacryloyldimethyl Taurate, Polygonum Bistorta Root Extract, Bacillus Ferment, Lecithin, Sodium Phytate, Coco-Caprylate/Caprate, Hexylene Glycol, Cetyl Hydroxyethylcellulose, Xanthan Gum, Ethylhexylglycerin, Caprylyl Glycol, Magnesium Chloride, Potassium Sorbate, Sodium Benzoate Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane. What it does: Dimethicone comes in different viscosities: Depending on the viscosity, dimethicone has different properties. Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity. This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient. Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Hexylene Glycol is a multitasker ingredient that works as a solvent, humectant, emulsifier, viscosity reducer, and preservative booster. It is able to dissolve both water and oil-soluble ingredients to stabilize tricky actives and make products spread more easily. As a humectant, it pulls water into the skin. But it's a pretty minor moisturizing ingredient compared to other humectants, like glycerin. Interestingly, it can act as a mild penetration enhancer. One in vitro study on human skin found a 12% concentration upped the absorption of mometasone furoate (a medicinal ingredient used to treat inflammatory skin conditions) up to 7%. This ingredient is typically used at levels of 0.1-10% depending on the role it's playing. A patch test study on eczema patients didn't find a si