Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Clinique Smart Clinical Repair Wrinkle Correcting Serum Versus Origins Plantscription Multi-Powered Youth Serum

Clinique Smart Clinical Repair Wrinkle Correcting Serum Versus Origins Plantscription Multi-Powered Youth Serum Detailed comparison of Clinique Smart Clinical Repair Wrinkle Correcting Serum versus Origins Plantscription Multi-Powered Youth Serum. This anti-ag

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Clinique Smart Clinical Repair Wrinkle Correcting Serum Versus Origins Plantscription Multi-Powered Youth Serum Detailed comparison of Clinique Smart Clinical Repair Wrinkle Correcting Serum versus Origins Plantscription Multi-Powered Youth Serum. This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Palmitoyl Tripeptide-1 to soften the look of wrinkles and refine skin texture. This anti-aging serum is formulated around Niacinamide and Acetyl Hexapeptide-8 to soften the look of wrinkles and refine skin texture. Water Dimethicone Isododecane Butylene Glycol Glycerin Polysilicone-11 Ascorbyl Glucoside Sodium Hyaluronate Tocopheryl Acetate Squalane Hypnea Musciformis Extract Gelidiella Acerosa Extract Sigesbeckia Orientalis Extract Helianthus Annuus Seed Extract Hordeum Vulgare Extract Triticum Vulgare Germ Extract Cucumis Sativus Fruit Extract Caffeine Acetyl Hexapeptide-8 Palmitoyl Tripeptide-1 Palmitoyl Tetrapeptide-7 Palmitoyl Hexapeptide-12 PEG-10 Dimethicone Glycyrrhetinic Acid Whey Protein Isohexadecane Propylene Glycol Dicaprate Caprylyl Glycol Hydroxypinacolone Retinoate Acetyl Glucosamine Cholesterol PEG-8 Faex Extract PEG-6 Dimethyl Isosorbide Glyceryl Polymethacrylate Polysorbate 20 Sodium Phosphate Synthetic Fluorphlogopite Polysorbate 80 Carbomer Hexylene Glycol Ammonium Acryloyldimethyltaurate/Vp Copolymer Acrylamide/Sodium Acryloyldimethyltaurate Copolymer Potassium Hydroxide Tin Oxide Disodium Phosphate Citric Acid Disodium EDTA Sodium Citrate Phenoxyethanol Potassium Sorbate CI 77891 Water, Dimethicone, Isododecane, Butylene Glycol, Glycerin, Polysilicone-11, Ascorbyl Glucoside, Sodium Hyaluronate, Tocopheryl Acetate, Squalane, Hypnea Musciformis Extract, Gelidiella Acerosa Extract, Sigesbeckia Orientalis Extract, Helianthus Annuus Seed Extract, Hordeum Vulgare Extract, Triticum Vulgare Germ Extract, Cucumis Sativus Fruit Extract, Caffeine, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, PEG-10 Dimethicone, Glycyrrhetinic Acid, Whey Protein, Isohexadecane, Propylene Glycol Dicaprate, Caprylyl Glycol, Hydroxypinacolone Retinoate, Acetyl Glucosamine, Cholesterol, PEG-8, Faex Extract, PEG-6, Dimethyl Isosorbide, Glyceryl Polymethacrylate, Polysorbate 20, Sodium Phosphate, Synthetic Fluorphlogopite, Polysorbate 80, Carbomer, Hexylene Glycol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Potassium Hydroxide, Tin Oxide, Disodium Phosphate, Citric Acid, Disodium EDTA, Sodium Citrate, Phenoxyethanol, Potassium Sorbate, CI 77891 Niacinamide Heptyl Undecylenate Octyldodecanol Glycereth-26 Sodium Acrylates Copolymer Algae Extract Illicium Verum Fruit/Seed Oil Citrus Aurantium Bergamia Fruit Oil Pelargonium Graveolens Flower Oil Lavandula Angustifolia Oil Citrus Limon Peel Oil Litsea Cubeba Fruit Oil Citrus Nobilis Peel Oil Myristica Fragrans Kernel Oil Citrus Aurantium Dulcis Oil Rosa Damascena Flower Oil Hibiscus Abelmoschus Extract Carthamus Tinctorius Seed Oil Linalool Geraniol Citronellol Limonene Anogeissus Leiocarpus Bark Extract Acetyl Octapeptide-3 Dipeptide Diaminobutyroyl Benzylamide Diacetate Commiphora Mukul Resin Extract Laminaria Saccharina Extract Glucosamine Hcl Bambusa Vulgaris Extract Rosmarinus Officinalis Leaf Extract Molasses Extract Scutellaria Baicalensis Root Extract Pyrus Malus Fruit Extract Pisum Sativum Extract Caprylic/Capric Triglyceride Lecithin Xanthan Gum Sodium Metabisulfite Sodium Sulfite Sodium Phytate BHT Essent Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Caffeine is a naturally occurring plant compound found in coffee beans, tea leaves, cocoa pods, and guarana. As an antioxidant, caffeine protects your skin from free radical damage caused by UV exposure and envionrmnetal stressors. Early research also shows that caffeine can help calm redness, soothe irritated skin, and support hair growth by stimulating microcirculation in the scalp. You might have seen eye creams marketing caffeine as a depuffing ingredient. This is because it is a vasoconstrictor meaning it can temporarily constrict blood vessels, though clinical evidence for this specific use is still limited. Most skincare products contain this ingredient at concentrations between 1-6%. It is able to penetrate skin easily regardless of skin type or thickness. Just so you know, a very small number of case reports describe caffeine-induced allergy. This ingredient is generally well-tolerated, non-irritating, and non-sensitizing for the majority of people. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Carbomer i