Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Clinique Smart Clinical Repair Wrinkle Correcting Serum Versus The INKEY List Retinol Serum

Clinique Smart Clinical Repair Wrinkle Correcting Serum Versus The INKEY List Retinol Serum Detailed comparison of Clinique Smart Clinical Repair Wrinkle Correcting Serum versus The INKEY List Retinol Serum. This anti-aging serum is formulated around Acetyl He

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Clinique Smart Clinical Repair Wrinkle Correcting Serum Versus The INKEY List Retinol Serum Detailed comparison of Clinique Smart Clinical Repair Wrinkle Correcting Serum versus The INKEY List Retinol Serum. This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Palmitoyl Tripeptide-1 to soften the look of wrinkles and refine skin texture. This anti-aging serum is formulated around Retinyl Acetate and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles and refine skin texture. Water Dimethicone Isododecane Butylene Glycol Glycerin Polysilicone-11 Ascorbyl Glucoside Sodium Hyaluronate Tocopheryl Acetate Squalane Hypnea Musciformis Extract Gelidiella Acerosa Extract Sigesbeckia Orientalis Extract Helianthus Annuus Seed Extract Hordeum Vulgare Extract Triticum Vulgare Germ Extract Cucumis Sativus Fruit Extract Caffeine Acetyl Hexapeptide-8 Palmitoyl Tripeptide-1 Palmitoyl Tetrapeptide-7 Palmitoyl Hexapeptide-12 PEG-10 Dimethicone Glycyrrhetinic Acid Whey Protein Isohexadecane Propylene Glycol Dicaprate Caprylyl Glycol Hydroxypinacolone Retinoate Acetyl Glucosamine Cholesterol PEG-8 Faex Extract PEG-6 Dimethyl Isosorbide Glyceryl Polymethacrylate Polysorbate 20 Sodium Phosphate Synthetic Fluorphlogopite Polysorbate 80 Carbomer Hexylene Glycol Ammonium Acryloyldimethyltaurate/Vp Copolymer Acrylamide/Sodium Acryloyldimethyltaurate Copolymer Potassium Hydroxide Tin Oxide Disodium Phosphate Citric Acid Disodium EDTA Sodium Citrate Phenoxyethanol Potassium Sorbate CI 77891 Water, Dimethicone, Isododecane, Butylene Glycol, Glycerin, Polysilicone-11, Ascorbyl Glucoside, Sodium Hyaluronate, Tocopheryl Acetate, Squalane, Hypnea Musciformis Extract, Gelidiella Acerosa Extract, Sigesbeckia Orientalis Extract, Helianthus Annuus Seed Extract, Hordeum Vulgare Extract, Triticum Vulgare Germ Extract, Cucumis Sativus Fruit Extract, Caffeine, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, PEG-10 Dimethicone, Glycyrrhetinic Acid, Whey Protein, Isohexadecane, Propylene Glycol Dicaprate, Caprylyl Glycol, Hydroxypinacolone Retinoate, Acetyl Glucosamine, Cholesterol, PEG-8, Faex Extract, PEG-6, Dimethyl Isosorbide, Glyceryl Polymethacrylate, Polysorbate 20, Sodium Phosphate, Synthetic Fluorphlogopite, Polysorbate 80, Carbomer, Hexylene Glycol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Potassium Hydroxide, Tin Oxide, Disodium Phosphate, Citric Acid, Disodium EDTA, Sodium Citrate, Phenoxyethanol, Potassium Sorbate, CI 77891 Propanediol Dicaprylyl Carbonate Retinyl Acetate Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Phospholipids Glycine Soja Oil Polysorbate 60 Glycolipids Sodium Hydroxide Sodium Phytate Sorbitan Isostearate Glycine Soja Sterols Tetrahexyldecyl Ascorbate Leuconostoc/Radish Root Ferment Filtrate Hyaluronic Acid Sodium Lactate Tocopherol Water, Glycerin, Butylene Glycol, Propanediol, Dicaprylyl Carbonate, Retinyl Acetate, Dimethicone, Phenoxyethanol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Caprylyl Glycol, Phospholipids, Squalane, Glycine Soja Oil, Carbomer, Polysorbate 60, Tocopheryl Acetate, Glycolipids, Sodium Hydroxide, Sodium Phytate, Sorbitan Isostearate, Glycine Soja Sterols, Tetrahexyldecyl Ascorbate, Leuconostoc/Radish Root Ferment Filtrate, Hyaluronic Acid, Sodium Lactate, Tocopherol, Polysorbate 20, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1 These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane. What it does: Dimethicone comes in different viscosities: Depending on the viscosity, dimethicone has different properties. Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity. This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient. Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and w