Ingredient or product comparison
Comprehensive Comparison: All Skin Peptides Ranked
This table compares every major peptide used for skin, ranked by strength of evidence, practical accessibility, and breadth of benefits. GHK-Cu Topical, injectable, nasal Collagen synthesis, wound healing, anti-inflammation Strong (clinical + gene data) 4-8 we
This source-based comparison does not add ratings or recommend a winner.
- This table compares every major peptide used for skin, ranked by strength of evidence, practical accessibility, and breadth of benefits.
- GHK-Cu
- Topical, injectable, nasal
- Collagen synthesis, wound healing, anti-inflammation
- Strong (clinical + gene data)
- 4-8 weeks
- $$-$$$
- Aging skin, scars, post-procedure
- Oral collagen peptides
- Oral supplement
- Hydration, elasticity, collagen density
- Strong (meta-analyses)
- 4-12 weeks
- $
- General anti-aging, beginners
- Matrixyl (pal-pentapeptide-4)
- Topical serum
- Collagen I/III stimulation
- Moderate (RCTs)
- 8-12 weeks
- $$
- Fine lines, daily maintenance
- Argireline (AH-3)
- Expression line relaxation
- 2-4 weeks
- Crow's feet, forehead lines
- BPC-157
- Injectable, oral
- Wound healing, angiogenesis
- Moderate (animal + clinical)
- $$$
- Post-surgical, chronic wounds
- TB-500
- Injectable
- Cell migration, tissue repair
- Moderate (animal studies)
- Deep injuries, burns
- Epitalon
- Telomere maintenance, anti-senescence
- Emerging (in vitro + clinical)
- 8-12+ weeks
- Long-term anti-aging
- Matrixyl 3000
- Collagen + anti-inflammatory
- Sensitive skin, rosacea-prone
- SNAP-8
- Enhanced muscle relaxation
- Limited (early studies)
- Deep expression lines
- Cost key: $ = under $30/month, $$ = $30-100/month, $$$ = over $100/month. Use the peptide cost calculator to estimate your specific protocol expenses.