Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Cos De BAHA Peptide Complex Facial Cream with Matrixyl 3000 & Argireline Versus Esfolio Peptide Facial Cream

Cos De BAHA Peptide Complex Facial Cream with Matrixyl 3000 & Argireline Versus Esfolio Peptide Facial Cream Detailed comparison of Cos De BAHA Peptide Complex Facial Cream with Matrixyl 3000 & Argireline versus Esfolio Peptide Facial Cream. This anti-aging mo

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Cos De BAHA Peptide Complex Facial Cream with Matrixyl 3000 & Argireline Versus Esfolio Peptide Facial Cream Detailed comparison of Cos De BAHA Peptide Complex Facial Cream with Matrixyl 3000 & Argireline versus Esfolio Peptide Facial Cream. This anti-aging moisturizer is formulated around Acetyl Hexapeptide-8 and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles. This anti-aging moisturizer is formulated around Niacinamide and Acetyl Hexapeptide-8 to soften the look of wrinkles. Aloe Barbadensis Leaf Extract Propanediol Caprylic/Capric Triglyceride Niacinamide 1,2-Hexanediol Cetearyl Olivate Cetearyl Alcohol Glyceryl Stearate Sorbitan Olivate Panthenol Acetyl Hexapeptide-8 Palmitoyl Tetrapeptide-7 Palmitoyl Tripeptide-1 Tocopheryl Acetate Butyrospermum Parkii Butter Argania Spinosa Kernel Oil Caffeine Allantoin Sodium Hyaluronate Dipotassium Glycyrrhizate Squalane Ceramide NP Adenosine Rosa Damascena Extract Lavandula Angustifolia Flower Extract Camellia Sinensis Leaf Extract Melissa Officinalis Leaf Extract Artemisia Vulgaris Extract Sorbitan Isostearate Polysorbate 60 Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Aloe Barbadensis Leaf Extract, Propanediol, Caprylic/Capric Triglyceride, Niacinamide, 1,2-Hexanediol, Cetearyl Olivate, Cetearyl Alcohol, Glyceryl Stearate, Sorbitan Olivate, Panthenol, Acetyl Hexapeptide-8, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Tocopheryl Acetate, Butyrospermum Parkii Butter, Argania Spinosa Kernel Oil, Caffeine, Allantoin, Sodium Hyaluronate, Dipotassium Glycyrrhizate, Squalane, Ceramide NP, Adenosine, Rosa Damascena Extract, Lavandula Angustifolia Flower Extract, Camellia Sinensis Leaf Extract, Melissa Officinalis Leaf Extract, Artemisia Vulgaris Extract, Sorbitan Isostearate, Polysorbate 60, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Water Glycerin Butylene Glycol Cetyl Alcohol Pentaerythrityl Tetraethylhexanoate Beeswax Trehalose Betaine Leontopodium Alpinum Callus Culture Extract Snail Secretion Filtrate Salix Alba Bark Extract Origanum Vulgare Leaf Extract Hydrolyzed Collagen Chamaecyparis Obtusa Leaf Extract Scutellaria Baicalensis Root Extract Portulaca Oleracea Extract Lactobacillus/Soybean Ferment Extract Cinnamomum Cassia Bark Extract Copper Tripeptide-1 Stearyl Alcohol Cyclopentasiloxane PEG-100 Stearate Dimethicone Cyclohexasiloxane Myristyl Alcohol Carbomer Arginine Ammonium Acryloyldimethyltaurate/Vp Copolymer Lauryl Alcohol Disodium EDTA Chlorphenesin Ethylhexylglycerin Caprylyl Glycol Parfum Limonene Linalool Citral Water, Glycerin, Caprylic/Capric Triglyceride, Butylene Glycol, Cetyl Alcohol, Pentaerythrityl Tetraethylhexanoate, Niacinamide, Glyceryl Stearate, Squalane, Beeswax, Trehalose, Betaine, Leontopodium Alpinum Callus Culture Extract, Snail Secretion Filtrate, Salix Alba Bark Extract, Origanum Vulgare Leaf Extract, Hydrolyzed Collagen, Chamaecyparis Obtusa Leaf Extract, Scutellaria Baicalensis Root Extract, Portulaca Oleracea Extract, Lactobacillus/Soybean Ferment Extract, Cinnamomum Cassia Bark Extract, Sodium Hyaluronate, Acetyl Hexapeptide-8, Copper Tripeptide-1, Stearyl Alcohol, Cyclopentasiloxane, PEG-100 Stearate, Dimethicone, Polysorbate 60, Cyclohexasiloxane, Myristyl Alcohol, Carbomer, Arginine, Tocopheryl Acetate, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Lauryl Alcohol, Adenosine, Disodium EDTA, Chlorphenesin, Ethylhexylglycerin, 1,2-Hexanediol, Caprylyl Glycol, Parfum, Limonene, Linalool, Citral These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. 1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. It is a: Humectant, drawing moisture into the skin Emollient, helping to soften skin Solvent, dispersing and stabilizing formulas Preservative booster, enhancing the antimicrobial activity of other preservatives Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent. The way it works is fairly well mapped out: Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going. The clinical backing is pretty solid too. A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months. A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration. On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses. This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization. Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it