Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Cosmedix Serum 24 Rapid Renewal Complex Versus PCA Skin Total Strength Serum

Cosmedix Serum 24 Rapid Renewal Complex Versus PCA Skin Total Strength Serum Detailed comparison of Cosmedix Serum 24 Rapid Renewal Complex versus PCA Skin Total Strength Serum. This anti-aging serum is formulated around Retinol and Retinal to soften the look

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Cosmedix Serum 24 Rapid Renewal Complex Versus PCA Skin Total Strength Serum Detailed comparison of Cosmedix Serum 24 Rapid Renewal Complex versus PCA Skin Total Strength Serum. This anti-aging serum is formulated around Retinol and Retinal to soften the look of wrinkles and refine skin texture. This anti-aging serum is formulated around Gluconolactone and Sh-Oligopeptide-1 to soften the look of wrinkles and refine skin texture. Water Hamamelis Virginiana Water Carthamus Tinctorius Oleosomes Phospholipids Glycerin Sodium Acrylates Copolymer Hydrogenated Polyisobutene Sodium Lactate Glycosaminoglycans Polysorbate 20 Cetyl Alcohol Retinol Retinal Proline Sodium Hyaluronate Helianthus Annuus Seed Oil Tapioca Starch Leuconostoc/Radish Root Ferment Filtrate Lonicera Caprifolium Flower Extract Lonicera Japonica Flower Extract Santalum Austrocaledonicum Wood Oil Lavandula Hybrida Oil Galactoarabinan Sodium Polygamma-Glutamate Tocopherol Squalane Hydroxypropyl Starch Phosphate Dimethicone Polyglyceryl-10 Stearate Gluconic Acid Xanthan Gum Tetrasodium EDTA Citric Acid Alcohol Potassium Sorbate Sodium Glycolate Sodium Hydroxide Trisodium EDTA Benzoic Acid Sodium Benzoate Linalool Limonene Water, Hamamelis Virginiana Water, Carthamus Tinctorius Oleosomes, Phospholipids, Glycerin, Sodium Acrylates Copolymer, Hydrogenated Polyisobutene, Sodium Lactate, Glycosaminoglycans, Polysorbate 20, Cetyl Alcohol, Retinol, Retinal, Proline, Sodium Hyaluronate, Helianthus Annuus Seed Oil, Tapioca Starch, Leuconostoc/Radish Root Ferment Filtrate, Lonicera Caprifolium Flower Extract, Lonicera Japonica Flower Extract, Santalum Austrocaledonicum Wood Oil, Lavandula Hybrida Oil, Galactoarabinan, Sodium Polygamma-Glutamate, Tocopherol, Squalane, Hydroxypropyl Starch Phosphate, Dimethicone, Polyglyceryl-10 Stearate, Gluconic Acid, Xanthan Gum, Tetrasodium EDTA, Citric Acid, Alcohol, Potassium Sorbate, Sodium Glycolate, Sodium Hydroxide, Trisodium EDTA, Benzoic Acid, Sodium Benzoate, Linalool, Limonene Alcohol Denat. Gluconolactone Hydroxypropyl Cyclodextrin Ammonium Acryloyldimethyltaurate/Vp Copolymer Cocos Nucifera Fruit Juice Adenosine Aesculus Hippocastanum Seed Extract Melaleuca Alternifolia Leaf Oil Menthyl Lactate Silybum Marianum Extract Totarol Tocotrienols Elaeis Guineensis Oil Sh-Oligopeptide-1 Palmitoyl Tripeptide-38 Water, Hamamelis Virginiana Water, Glycerin, Glycosaminoglycans, Alcohol, Alcohol Denat., Gluconolactone, Hydroxypropyl Cyclodextrin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Sodium Benzoate, Xanthan Gum, Lonicera Caprifolium Flower Extract, Cocos Nucifera Fruit Juice, Adenosine, Aesculus Hippocastanum Seed Extract, Lavandula Hybrida Oil, Lonicera Japonica Flower Extract, Melaleuca Alternifolia Leaf Oil, Menthyl Lactate, Santalum Austrocaledonicum Wood Oil, Silybum Marianum Extract, Sodium Hyaluronate, Totarol, Tocotrienols, Elaeis Guineensis Oil, Citric Acid, Phospholipids, Potassium Sorbate, Tocopherol, Sh-Oligopeptide-1, Palmitoyl Tripeptide-38 These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. This ingredient is also called ethanol or ethyl alcohol. It is denatured, meaning made undrinkable for cosmetic use. In formulas, it: Is it bad for your skin? The answer comes down to concentration. Patch and wash studies have found highly concentrated alcohol-based hand rubs (60-100%) cause less barrier disruption than washing with a basic detergent like SLS. The only measurable effect in these studies was a temporary dip in skin hydration. Concentrations below 12-15% in leave-on cosmetics is generally well-tolerated. Concentrations above start to see increased transepidermal water loss (TEWL) and reduced hydration. In concentrations about 58%, it creates temporary channels in your skin's lipid layers to become more permeable and allow other ingredients to slip through easily. This ingredient can be up to 80% of the formula in alcohol-based perfumes. Overall, this ingredient is probably harmless if found lower down an ingredients list but worth side-eyeing if it's high up (especially if your barrier is already struggling). Alcohol can worsen dry skin, eczema, and oily skin, especially at higher concentrations. This is because it can increase transepidermal water loss and decrease hydration to disrupt the skin barrier. According to the National Rosacea Society based in the US, you should be mindful of products with these alcohols in the top half of ingredients. True allergic contact dermatitis to ethanol is uncommon, but be sure to patch test if you have dry or sensitive skin. Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes. Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath. However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products. Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH. In skincare formulas, citric acid can: While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants. Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations. Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger. However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliat