Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

D'Alba Peptide No Sebum Repair Cream Versus Tosowoong Adenosine Cica Cream

D'Alba Peptide No Sebum Repair Cream Versus Tosowoong Adenosine Cica Cream Detailed comparison of D'Alba Peptide No Sebum Repair Cream versus Tosowoong Adenosine Cica Cream. This oil-control moisturizer is formulated around Niacinamide and Acetyl Hexapeptide-8

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D'Alba Peptide No Sebum Repair Cream Versus Tosowoong Adenosine Cica Cream Detailed comparison of D'Alba Peptide No Sebum Repair Cream versus Tosowoong Adenosine Cica Cream. This oil-control moisturizer is formulated around Niacinamide and Acetyl Hexapeptide-8 to balance excess oil and strengthen the skin barrier. This calming moisturizer is formulated around Centella Asiatica Extract and Niacinamide to calm redness and soften the look of wrinkles. Water Butylene Glycol Glycerin Caprylic/Capric Triglyceride Squalane 1,2-Hexanediol Niacinamide Cetearyl Olivate Sorbitan Olivate Dimethicone Cetearyl Alcohol Cetearyl Glucoside Carbomer Hydroxypropyl Methylcellulose Artemisia Annua Extract Nelumbo Nucifera Flower Extract Oryza Sativa Extract Saccharomyces Ferment Arginine Octyldodecanol Panthenol Melaleuca Alternifolia Leaf Extract Helianthus Annuus Seed Oil Lavandula Angustifolia Oil Pullulan Tuber Magnatum Extract Calamine Centella Asiatica Extract Dipotassium Glycyrrhizate Tocopheryl Acetate Ethylhexylglycerin Adenosine Sodium Hyaluronate Hydrogenated Lecithin Pentylene Glycol Ceramide NP Polygonum Cuspidatum Root Extract Scutellaria Baicalensis Root Extract Biosaccharide Gum-1 Alkanna Tinctoria Root Extract Caprylyl Glycol Betaine Salicylate Camellia Sinensis Leaf Extract Glycyrrhiza Glabra Root Extract Chamomilla Recutita Flower Extract Porphyridium Cruentum Extract Rosmarinus Officinalis Leaf Extract Glucose Sodium Hyaluronate Crosspolymer Acetyl Hexapeptide-8 Hydrolyzed Hyaluronic Acid Hyaluronic Acid Tocopherol Hydrolyzed Sodium Hyaluronate Water, Butylene Glycol, Glycerin, Caprylic/Capric Triglyceride, Squalane, 1,2-Hexanediol, Niacinamide, Cetearyl Olivate, Sorbitan Olivate, Dimethicone, Cetearyl Alcohol, Cetearyl Glucoside, Carbomer, Hydroxypropyl Methylcellulose, Artemisia Annua Extract, Nelumbo Nucifera Flower Extract, Oryza Sativa Extract, Saccharomyces Ferment, Arginine, Octyldodecanol, Panthenol, Melaleuca Alternifolia Leaf Extract, Helianthus Annuus Seed Oil, Lavandula Angustifolia Oil, Pullulan, Tuber Magnatum Extract, Calamine, Centella Asiatica Extract, Dipotassium Glycyrrhizate, Tocopheryl Acetate, Ethylhexylglycerin, Adenosine, Sodium Hyaluronate, Hydrogenated Lecithin, Pentylene Glycol, Ceramide NP, Polygonum Cuspidatum Root Extract, Scutellaria Baicalensis Root Extract, Biosaccharide Gum-1, Alkanna Tinctoria Root Extract, Caprylyl Glycol, Betaine Salicylate, Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra Root Extract, Chamomilla Recutita Flower Extract, Porphyridium Cruentum Extract, Rosmarinus Officinalis Leaf Extract, Glucose, Sodium Hyaluronate Crosspolymer, Acetyl Hexapeptide-8, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid, Tocopherol, Hydrolyzed Sodium Hyaluronate Isopropyl Isostearate Butyrospermum Parkii Butter Stearic Acid Stearyl Alcohol C12-16 Alcohols Sodium Polyacryloyldimethyl Taurate Dipropylene Glycol Sorbitan Stearate Hydroxyacetophenone Hydrogenated Polydecene Palmitic Acid Hydroxyethylcellulose Trideceth-10 Disodium EDTA Allantoin Allium Cepa Bulb Extract Ectoin Trehalose Carum Petroselinum Extract Brassica Oleracea Capitata Leaf Extract Propanediol Persea Gratissima Oil Copernicia Cerifera Wax Simmondsia Chinensis Seed Oil Hydrogenated Polyisobutene Artemisia Vulgaris Extract Houttuynia Cordata Extract Sophora Flavescens Root Extract Psoralea Corylifolia Fruit Extract Platycarya Strobilacea Extract Polyglyceryl-10 Oleate Centella Asiatica Leaf Extrac These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. 1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. It is a: Humectant, drawing moisture into the skin Emollient, helping to soften skin Solvent, dispersing and stabilizing formulas Preservative booster, enhancing the antimicrobial activity of other preservatives Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent. The way it works is fairly well mapped out: Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going. The clinical backing is pretty solid too. A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months. A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration. On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses. This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization. Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it