Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Dear, Klairs Midnight Blue Calming Cream Versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer

Dear, Klairs Midnight Blue Calming Cream Versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer Detailed comparison of Dear, Klairs Midnight Blue Calming Cream versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer. This calming moisturizer is fo

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Dear, Klairs Midnight Blue Calming Cream Versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer Detailed comparison of Dear, Klairs Midnight Blue Calming Cream versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer. This calming moisturizer is formulated around Centella Asiatica Extract and Ceramide NP to calm redness and strengthen the skin barrier. This anti-aging night moisturizer is formulated around Retinol and Niacinamide to soften the look of wrinkles and refine skin texture. Water Cetyl Ethylhexanoate Butylene Glycol Glycerin Sodium Hyaluronate Caprylic/Capric Triglyceride Centella Asiatica Extract Sorbitan Stearate Cetyl Alcohol Butyrospermum Parkii Butter Argania Spinosa Kernel Oil Simmondsia Chinensis Seed Oil Sorbitan Sesquioleate Glyceryl Stearate Stearic Acid Portulaca Oleracea Extract Anthemis Nobilis Flower Extract Ceramide NP Polysorbate 60 Candelilla Cera Chlorphenesin Tocopheryl Acetate Xanthan Gum Acrylates/C10-30 Alkyl Acrylate Crosspolymer Morus Alba Root Extract Tromethamine Brassica Oleracea Italica Extract Guaiazulene Acetyl Hexapeptide-8 Lecithin Acetyl Glutamine Sh-Oligopeptide-1 Sh-Oligopeptide-2 Sh-Polypeptide-1 Sh-Polypeptide-9 Sh-Polypeptide-11 Bacillus/Folic Acid/Soybean Ferment Extract Caprylyl Glycol 1,2-Hexanediol Water, Cetyl Ethylhexanoate, Butylene Glycol, Glycerin, Sodium Hyaluronate, Caprylic/Capric Triglyceride, Centella Asiatica Extract, Sorbitan Stearate, Cetyl Alcohol, Butyrospermum Parkii Butter, Argania Spinosa Kernel Oil, Simmondsia Chinensis Seed Oil, Sorbitan Sesquioleate, Glyceryl Stearate, Stearic Acid, Portulaca Oleracea Extract, Anthemis Nobilis Flower Extract, Ceramide NP, Polysorbate 60, Candelilla Cera, Chlorphenesin, Tocopheryl Acetate, Xanthan Gum, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Morus Alba Root Extract, Tromethamine, Brassica Oleracea Italica Extract, Guaiazulene, Acetyl Hexapeptide-8, Lecithin, Acetyl Glutamine, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Bacillus/Folic Acid/Soybean Ferment Extract, Caprylyl Glycol, 1,2-Hexanediol Dimethicone Tapioca Starch Dimethicone Crosspolymer Retinol Retinyl Propionate Niacinamide Palmitoyl Pentapeptide-4 Polyacrylamide C13-14 Isoparaffin DMDM Hydantoin Polysorbate 20 Laureth-4 Laureth-7 Dimethiconol Polymethylsilsesquioxane Aminomethyl Propanol Titanium Dioxide Disodium EDTA Iodopropynyl Butylcarbamate Water, Dimethicone, Glycerin, Tapioca Starch, Dimethicone Crosspolymer, Retinol, Retinyl Propionate, Niacinamide, Palmitoyl Pentapeptide-4, Polyacrylamide, C13-14 Isoparaffin, DMDM Hydantoin, Polysorbate 20, Laureth-4, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Laureth-7, Dimethiconol, Polymethylsilsesquioxane, Aminomethyl Propanol, Titanium Dioxide, Disodium EDTA, Iodopropynyl Butylcarbamate, Caprylic/Capric Triglyceride These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products. As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied. It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin. A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record. Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss. Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid. In practice, that translates to a long shelf life and a consistently elegant skin feel. While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns. Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source. This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out. This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Water. It's the most common cosmetic ingredient of all. You'll