Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Dear, Klairs Midnight Blue Calming Cream Versus Paula's Choice Omega+ Complex Moisturizer

Dear, Klairs Midnight Blue Calming Cream Versus Paula's Choice Omega+ Complex Moisturizer Detailed comparison of Dear, Klairs Midnight Blue Calming Cream versus Paula's Choice Omega+ Complex Moisturizer. This calming moisturizer is formulated around Centella A

This source-based comparison does not add ratings or recommend a winner.

Dear, Klairs Midnight Blue Calming Cream Versus Paula's Choice Omega+ Complex Moisturizer Detailed comparison of Dear, Klairs Midnight Blue Calming Cream versus Paula's Choice Omega+ Complex Moisturizer. This calming moisturizer is formulated around Centella Asiatica Extract and Ceramide NP to calm redness and strengthen the skin barrier. This barrier-repair moisturizer is formulated around Butyrospermum Parkii Butter and Linoleic Acid to strengthen the skin barrier and hydrate skin. Water Cetyl Ethylhexanoate Butylene Glycol Glycerin Sodium Hyaluronate Caprylic/Capric Triglyceride Centella Asiatica Extract Sorbitan Stearate Cetyl Alcohol Butyrospermum Parkii Butter Argania Spinosa Kernel Oil Simmondsia Chinensis Seed Oil Sorbitan Sesquioleate Glyceryl Stearate Stearic Acid Portulaca Oleracea Extract Anthemis Nobilis Flower Extract Ceramide NP Polysorbate 60 Candelilla Cera Chlorphenesin Tocopheryl Acetate Xanthan Gum Acrylates/C10-30 Alkyl Acrylate Crosspolymer Morus Alba Root Extract Tromethamine Brassica Oleracea Italica Extract Guaiazulene Acetyl Hexapeptide-8 Lecithin Acetyl Glutamine Sh-Oligopeptide-1 Sh-Oligopeptide-2 Sh-Polypeptide-1 Sh-Polypeptide-9 Sh-Polypeptide-11 Bacillus/Folic Acid/Soybean Ferment Extract Caprylyl Glycol 1,2-Hexanediol Water, Cetyl Ethylhexanoate, Butylene Glycol, Glycerin, Sodium Hyaluronate, Caprylic/Capric Triglyceride, Centella Asiatica Extract, Sorbitan Stearate, Cetyl Alcohol, Butyrospermum Parkii Butter, Argania Spinosa Kernel Oil, Simmondsia Chinensis Seed Oil, Sorbitan Sesquioleate, Glyceryl Stearate, Stearic Acid, Portulaca Oleracea Extract, Anthemis Nobilis Flower Extract, Ceramide NP, Polysorbate 60, Candelilla Cera, Chlorphenesin, Tocopheryl Acetate, Xanthan Gum, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Morus Alba Root Extract, Tromethamine, Brassica Oleracea Italica Extract, Guaiazulene, Acetyl Hexapeptide-8, Lecithin, Acetyl Glutamine, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Bacillus/Folic Acid/Soybean Ferment Extract, Caprylyl Glycol, 1,2-Hexanediol Ceteareth-6 Olivate C13-15 Alkane Polyglyceryl-4 Laurate Decyl Oleate Linum Usitatissimum Seed Oil Salvia Hispanica Seed Oil Olea Europaea Fruit Oil Passiflora Edulis Seed Oil Borago Officinalis Seed Oil Hydrogenated Olive Oil Psidium Guajava Fruit Extract Olea Europaea Oil Unsaponifiables Limnanthes Alba Seed Oil Linoleic Acid Linolenic Acid Oleic Acid Euterpe Oleracea Sterols Ceramide AP Ceramide EOP Serine Alanine Glycine Proline Lysine Hcl Threonine Arginine Squalane Cholesterol Phytosphingosine Anastatica Hierochuntica Extract Sodium Lactate Boerhavia Diffusa Root Extract Adenosine Phytic Acid Glutamic Acid Betaine Pullulan PCA Sodium PCA Carbomer Sodium Polyacrylate Starch Sclerotium Gum Sodium Lauroyl Lactylate Phenoxyethanol Ethylhexylglycerin Water, Butyrospermum Parkii Butter, Ceteareth-6 Olivate, Butylene Glycol, C13-15 Alkane, Glycerin, Glyceryl Stearate, Polyglyceryl-4 Laurate, Decyl Oleate, Linum Usitatissimum Seed Oil, Salvia Hispanica Seed Oil, Olea Europaea Fruit Oil, Passiflora Edulis Seed Oil, Borago Officinalis Seed Oil, Hydrogenated Olive Oil, Psidium Guajava Fruit Extract, Olea Europaea Oil Unsaponifiables, Limnanthes Alba Seed Oil, Linoleic Acid, Linolenic Acid, Oleic Acid, Euterpe Oleracea Sterols, Ceramide AP, Ceramide EOP, Ceramide NP, Serine, Alanine, Glycine, Proline, Lysine Hcl, Threonine, Arginine, Squalane, Cholesterol, Phytosphingosine, Anastatic These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. This ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients. Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL). In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!). Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo. Shea butter also contains vitamins A and E which may contribute to antioxidant activity. While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement. This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize. Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids. Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes. This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants. A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%. Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days. Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient. Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elas