Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Depology Peptide Complex 10% Wrinkle Defense Serum Versus Skin Deva 20% Argireline + Matrixyl 3000 + Hyaluronic Acid Serum

Depology Peptide Complex 10% Wrinkle Defense Serum Versus Skin Deva 20% Argireline + Matrixyl 3000 + Hyaluronic Acid Serum Detailed comparison of Depology Peptide Complex 10% Wrinkle Defense Serum versus Skin Deva 20% Argireline + Matrixyl 3000 + Hyaluronic Ac

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Depology Peptide Complex 10% Wrinkle Defense Serum Versus Skin Deva 20% Argireline + Matrixyl 3000 + Hyaluronic Acid Serum Detailed comparison of Depology Peptide Complex 10% Wrinkle Defense Serum versus Skin Deva 20% Argireline + Matrixyl 3000 + Hyaluronic Acid Serum. This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Palmitoyl Tripeptide-5 to soften the look of wrinkles. This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Matrixyl 3000 to soften the look of wrinkles and hydrate skin. Water Isopentyldiol 1,2-Hexanediol Panthenol Hydroxyethyl Urea Butylene Glycol Propanediol Caprylyl Glycol Glycerin Sodium Hyaluronate Ficus Carica Fruit Extract Centella Asiatica Extract Acetyl Hexapeptide-8 Ceramide NP Hydrogenated Lecithin Anthemis Nobilis Flower Oil Tocopherol Houttuynia Cordata Extract Tocopheryl Acetate Ascorbic Acid Polypeptide Ammonium Acryloyldimethyltaurate/Vp Copolymer Tromethamine Carbomer Octyldodeceth-16 Ethylhexylglycerin Acrylates/C10-30 Alkyl Acrylate Crosspolymer Disodium EDTA Palmitoyl Tripeptide-5 Pinus Strobus Bark Extract Hexapeptide-9 Maltodextrin Lavandula Angustifolia Oil Linalool Water, Isopentyldiol, 1,2-Hexanediol, Panthenol, Hydroxyethyl Urea, Butylene Glycol, Propanediol, Caprylyl Glycol, Glycerin, Sodium Hyaluronate, Ficus Carica Fruit Extract, Centella Asiatica Extract, Acetyl Hexapeptide-8, Ceramide NP, Hydrogenated Lecithin, Anthemis Nobilis Flower Oil, Tocopherol, Houttuynia Cordata Extract, Tocopheryl Acetate, Ascorbic Acid Polypeptide, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Tromethamine, Carbomer, Octyldodeceth-16, Ethylhexylglycerin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Disodium EDTA, Palmitoyl Tripeptide-5, Pinus Strobus Bark Extract, Hexapeptide-9, Maltodextrin, Lavandula Angustifolia Oil, Linalool Matrixyl 3000 Aloe Barbadensis Sprout Hyaluronic Acid Benzyl Alcohol Dehydroacetic Acid Water, Acetyl Hexapeptide-8, Matrixyl 3000, Aloe Barbadensis Sprout, Glycerin, Hyaluronic Acid, Benzyl Alcohol, Dehydroacetic Acid These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product. So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation. You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!