Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Derma E Skin De-Stress Calming CBD Serum Versus Paula's Choice CBD Skin Transformative Treatment Milk

Derma E Skin De-Stress Calming CBD Serum Versus Paula's Choice CBD Skin Transformative Treatment Milk Detailed comparison of Derma E Skin De-Stress Calming CBD Serum versus Paula's Choice CBD Skin Transformative Treatment Milk. This calming serum is formulated

This source-based comparison does not add ratings or recommend a winner.

Derma E Skin De-Stress Calming CBD Serum Versus Paula's Choice CBD Skin Transformative Treatment Milk Detailed comparison of Derma E Skin De-Stress Calming CBD Serum versus Paula's Choice CBD Skin Transformative Treatment Milk. This calming serum is formulated around Aloe Barbadensis Leaf Juice and Cannabidiol - Synthetically Produced to calm redness and hydrate skin. This calming serum is formulated around Cannabidiol - Synthetically Produced and Centella Asiatica Extract to calm redness and strengthen the skin barrier. Water Aloe Barbadensis Leaf Juice Glycerin Cetyl Alcohol Caprylic/Capric Triglyceride Macadamia Ternifolia Seed Oil Glyceryl Stearate Citrate Cannabidiol - Synthetically Produced Cannabis Sativa Seed Oil Cannabis Sativa Flower/Leaf/Stem Extract Panthenol Allantoin Tocopheryl Acetate Ascorbyl Palmitate Chamomilla Recutita Flower Extract Pinus Pinaster Bark Extract Xanthan Gum Dimethicone Glyceryl Stearate Coco-Caprylate Cetearyl Glucoside Potassium Cetyl Phosphate Magnesium Aluminum Silicate Phenoxyethanol Ethylhexylglycerin Water, Aloe Barbadensis Leaf Juice, Glycerin, Cetyl Alcohol, Caprylic/Capric Triglyceride, Macadamia Ternifolia Seed Oil, Glyceryl Stearate Citrate, Cannabidiol - Synthetically Produced, Cannabis Sativa Seed Oil, Cannabis Sativa Flower/Leaf/Stem Extract, Panthenol, Allantoin, Tocopheryl Acetate, Ascorbyl Palmitate, Chamomilla Recutita Flower Extract, Pinus Pinaster Bark Extract, Xanthan Gum, Dimethicone, Glyceryl Stearate, Coco-Caprylate, Cetearyl Glucoside, Potassium Cetyl Phosphate, Magnesium Aluminum Silicate, Phenoxyethanol, Ethylhexylglycerin Squalane Simmondsia Chinensis Seed Oil Hydrogenated Lecithin Helianthus Annuus Seed Oil Borago Officinalis Seed Oil Centella Asiatica Extract Limnanthes Alba Seed Oil Linum Usitatissimum Seed Oil Lupinus Albus Seed Oil Phospholipids Sodium Hyaluronate Lecithin Tocopherol Sodium PCA Sodium Phytate Polyglyceryl-3 Stearate Pullulan Sclerotium Gum Hexylene Glycol Caprylyl Glycol Water, Glycerin, Caprylic/Capric Triglyceride, Squalane, Simmondsia Chinensis Seed Oil, Hydrogenated Lecithin, Helianthus Annuus Seed Oil, Cannabidiol - Synthetically Produced, Cannabis Sativa Seed Oil, Borago Officinalis Seed Oil, Centella Asiatica Extract, Limnanthes Alba Seed Oil, Linum Usitatissimum Seed Oil, Lupinus Albus Seed Oil, Phospholipids, Sodium Hyaluronate, Lecithin, Tocopherol, Sodium PCA, Panthenol, Sodium Phytate, Tocopheryl Acetate, Xanthan Gum, Glyceryl Stearate Citrate, Polyglyceryl-3 Stearate, Pullulan, Sclerotium Gum, Hexylene Glycol, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Synthethically produce Cannabidiol is a psychoactive substance made to mimic the effects of cannabis. Cannabis Sativa Seed Oil is the fixed oil expressed from the seeds of the Cannabis sativa plant. This is also known as hemp oil. Hemp oil is an emollient and nourishes the skin. It contains many fatty acids such as linoleic acid, amino acids, phospholipids, and vitamin E. The difference between hemp and cannabis is their psychoactive component. Hemp has low amounts of THC. Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss. Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid. In practice, that translates to a long shelf life and a consistently elegant skin feel. While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns. Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source. This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out. This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%. Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that: The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure. Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and