Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Dr. Althea 345 Relief Cream Versus Mary & May Calendula Peptide Ageless Sleeping Mask

Dr. Althea 345 Relief Cream Versus Mary & May Calendula Peptide Ageless Sleeping Mask Detailed comparison of Dr. Althea 345 Relief Cream versus Mary & May Calendula Peptide Ageless Sleeping Mask Korea. This calming moisturizer is formulated around Melaleuca Al

This source-based comparison does not add ratings or recommend a winner.

Dr. Althea 345 Relief Cream Versus Mary & May Calendula Peptide Ageless Sleeping Mask Detailed comparison of Dr. Althea 345 Relief Cream versus Mary & May Calendula Peptide Ageless Sleeping Mask Korea. This calming moisturizer is formulated around Melaleuca Alternifolia Leaf Water and Niacinamide to calm redness and strengthen the skin barrier. This anti-aging overnight mask is formulated around Acetyl Hexapeptide-8 and Copper Tripeptide-1 to soften the look of wrinkles and refine skin texture. No concerns Water Melaleuca Alternifolia Leaf Water Propanediol Glycerin 1,2-Hexanediol Hydrogenated Polydecene Vinyldimethicone C14-22 Alcohols Niacinamide Caprylic/Capric Triglyceride Panthenol Dicaprylyl Carbonate Butylene Glycol Ammonium Acryloyldimethyltaurate/Vp Copolymer Caprylyl Methicone Polymethylsilsesquioxane C12-20 Alkyl Glucoside Hydroxyacetophenone Acrylates/C10-30 Alkyl Acrylate Crosspolymer Polyquaternium-51 Ethylhexylglycerin Tromethamine Sodium Hyaluronate Sodium Stearoyl Glutamate Coptis Japonica Root Extract Centella Asiatica Leaf Water Beta-Glucan Resveratrol Hydrolyzed Hyaluronic Acid Camellia Sinensis Leaf Water Tocopherol Madecassoside Sodium DNA Centella Asiatica Extract Ceramide NP Tannic Acid Disodium EDTA Sodium Phytate Water, Melaleuca Alternifolia Leaf Water, Propanediol, Glycerin, 1,2-Hexanediol, Hydrogenated Polydecene, Vinyldimethicone, C14-22 Alcohols, Niacinamide, Caprylic/Capric Triglyceride, Panthenol, Dicaprylyl Carbonate, Butylene Glycol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Caprylyl Methicone, Polymethylsilsesquioxane, C12-20 Alkyl Glucoside, Hydroxyacetophenone, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Polyquaternium-51, Ethylhexylglycerin, Tromethamine, Sodium Hyaluronate, Sodium Stearoyl Glutamate, Coptis Japonica Root Extract, Centella Asiatica Leaf Water, Beta-Glucan, Resveratrol, Hydrolyzed Hyaluronic Acid, Camellia Sinensis Leaf Water, Tocopherol, Madecassoside, Sodium DNA, Centella Asiatica Extract, Ceramide NP, Tannic Acid, Disodium EDTA, Sodium Phytate Alcohol Denat. Methylpropanediol Betaine Dipropylene Glycol Gardenia Taitensis Callus Extract Oak Root Extract Tremella Fuciformis Extract Ficus Carica Fruit Extract Orchid Leaf/Root/Stem Extract Chamomilla Recutita Extract Chrysanthemum Parthenium Extract Hydrogenated Lecithin Polyglyceryl-10 Laurate Dextrin Acetyl Hexapeptide-8 Acetyl Octapeptide-3 Acetyl Tetrapeptide-2 Oligopeptide-6 Tripeptide-1 Copper Tripeptide-1 Hexapeptide-2 Dipeptide-2 Acetyl Tetrapeptide-3 Acetyl Tripeptide-1 Hexapeptide-9 Tripeptide-2 Nonapeptide-1 Pentapeptide-3 Tripeptide-3 Alanine/Histidine/Lysine Polypeptide Copper Hcl Dipeptide-4 Acetyl Tetrapeptide-5 Palmitoyl Dipeptide-7 Palmitoyl Hexapeptide-12 Palmitoyl Tripeptide-1 Palmitoyl Tripeptide-5 Palmitoyl Pentapeptide-4 Dipeptide Diaminobutyroyl Benzylamide Diacetate Palmitoyl Tetrapeptide-7 Guaiazulene Parfum Water, Alcohol Denat., Methylpropanediol, 1,2-Hexanediol, Betaine, Dipropylene Glycol, Gardenia Taitensis Callus Extract, Oak Root Extract, Tremella Fuciformis Extract, Centella Asiatica Extract, Ficus Carica Fruit Extract, Orchid Leaf/Root/Stem Extract, Chamomilla Recutita Extract, Chrysanthemum Parthenium Extract, Hydrogenated Lecithin, Sodium Hyaluronate, Panthenol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Glycerin, Tromethamine, Butylene Glycol, Polyglyceryl-10 Laurate, Dextrin, Sodium Phytate, Ceramide NP, Tocopherol, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Acetyl Tetrapeptide-2, Oligopeptide-6, These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. 1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. It is a: Humectant, drawing moisture into the skin Emollient, helping to soften skin Solvent, dispersing and stabilizing formulas Preservative booster, enhancing the antimicrobial activity of other preservatives Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products. As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied. It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin. A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Centella Asiatica Extract (Centella) is one of the most researched botanical extracts in skincare with decades of studies backing its effects on inflammation, collagen, and the skin barrier. That research keeps pointing back to the same four triterpenoid saponins: Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid. These compounds allow centella to dial back inflammation, encourage the skin to build and hold onto collagen, support the barrier and hydration, and bring solid antioxidant activity to protect against signs of aging. Centella also carries a nice supporting cast of Vitamin A, vitamin C, several B vitamins, and amino acids. Put it all together and you get an ingredient that soothes, hydrates, and protects, all at once. Most of centella's magic comes from the four big compounds (Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid). These are the actives doing the heavy lifting in almost every centella study. Here is the short version of what they do in the skin: So it is not just soothing for the sake of soothing. Centella calms the skin AND helps it rebuild. Just FYI, not all centella on an ingredient list is the same. What you are getting actually depends on the extract: Fun fact on the ratios: the leaves tend to be richest in Madecassoside and Asiaticoside, and lower in the two acids. The exact amounts shift with where the plant is grown and how it is processed. This means purity really does vary brand to brand. Centella is one of the most easygoing actives out there. It layers well with basically everything: niacinamide, hyaluronic acid, peptides, and vitamin C, and also pairs