Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Dr. Althea 345 Relief Cream Versus Paula's Choice Pro-Collagen Peptide Plumping Moisturizer

Dr. Althea 345 Relief Cream Versus Paula's Choice Pro-Collagen Peptide Plumping Moisturizer Detailed comparison of Dr. Althea 345 Relief Cream versus Paula's Choice Pro-Collagen Peptide Plumping Moisturizer. This calming moisturizer is formulated around Melale

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Dr. Althea 345 Relief Cream Versus Paula's Choice Pro-Collagen Peptide Plumping Moisturizer Detailed comparison of Dr. Althea 345 Relief Cream versus Paula's Choice Pro-Collagen Peptide Plumping Moisturizer. This calming moisturizer is formulated around Melaleuca Alternifolia Leaf Water and Niacinamide to calm redness and strengthen the skin barrier. This anti-aging moisturizer is formulated around Squalane to soften the look of wrinkles and hydrate skin. Water Melaleuca Alternifolia Leaf Water Propanediol Glycerin 1,2-Hexanediol Hydrogenated Polydecene Vinyldimethicone C14-22 Alcohols Niacinamide Caprylic/Capric Triglyceride Panthenol Dicaprylyl Carbonate Butylene Glycol Ammonium Acryloyldimethyltaurate/Vp Copolymer Caprylyl Methicone Polymethylsilsesquioxane C12-20 Alkyl Glucoside Hydroxyacetophenone Acrylates/C10-30 Alkyl Acrylate Crosspolymer Polyquaternium-51 Ethylhexylglycerin Tromethamine Sodium Hyaluronate Sodium Stearoyl Glutamate Coptis Japonica Root Extract Centella Asiatica Leaf Water Beta-Glucan Resveratrol Hydrolyzed Hyaluronic Acid Camellia Sinensis Leaf Water Tocopherol Madecassoside Sodium DNA Centella Asiatica Extract Ceramide NP Tannic Acid Disodium EDTA Sodium Phytate Water, Melaleuca Alternifolia Leaf Water, Propanediol, Glycerin, 1,2-Hexanediol, Hydrogenated Polydecene, Vinyldimethicone, C14-22 Alcohols, Niacinamide, Caprylic/Capric Triglyceride, Panthenol, Dicaprylyl Carbonate, Butylene Glycol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Caprylyl Methicone, Polymethylsilsesquioxane, C12-20 Alkyl Glucoside, Hydroxyacetophenone, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Polyquaternium-51, Ethylhexylglycerin, Tromethamine, Sodium Hyaluronate, Sodium Stearoyl Glutamate, Coptis Japonica Root Extract, Centella Asiatica Leaf Water, Beta-Glucan, Resveratrol, Hydrolyzed Hyaluronic Acid, Camellia Sinensis Leaf Water, Tocopherol, Madecassoside, Sodium DNA, Centella Asiatica Extract, Ceramide NP, Tannic Acid, Disodium EDTA, Sodium Phytate Dimethicone Squalane Pyrus Malus Fruit Extract Pentylene Glycol Sodium Acrylates Copolymer Gigartina Stellata Extract Acetyl Sh-Hexapeptide-5 Amide Acetate Tridecapeptide-1 Oligopeptide-1 Lecithin Hydroxypropyltrimonium Hyaluronate Cyanocobalamin Phenoxyethanol Water, Dimethicone, Squalane, Glycerin, Pyrus Malus Fruit Extract, Pentylene Glycol, 1,2-Hexanediol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Butylene Glycol, Hydroxyacetophenone, Sodium Acrylates Copolymer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Gigartina Stellata Extract, Acetyl Sh-Hexapeptide-5 Amide Acetate, Tridecapeptide-1, Oligopeptide-1, Sodium Phytate, Propanediol, Lecithin, Hydroxypropyltrimonium Hyaluronate, Cyanocobalamin, Phenoxyethanol These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. 1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. It is a: Humectant, drawing moisture into the skin Emollient, helping to soften skin Solvent, dispersing and stabilizing formulas Preservative booster, enhancing the antimicrobial activity of other preservatives Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products. As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied. It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin. A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record. Ammonium Acryloyldimethyltaurate/Vp Copolymer is a synthetically created polymer. It's used as a film-forming agent and used to thicken the consistency of products. Think of it as a supportive ingredient that helps your gel-creams feel silky, "cloud cream-like", and spread evenly without being greasy. The Cosmetic Ingredient Review (CIR) Expert Panel evaluated it (along with 22 other acryloyldimethyltaurate polymers) and concluded it's: Due to its large molecular size, it sits on the surface of skin rather than penetrating it. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Hydroxyacetophenone is a small phenolic molecule that earns its place in a formulas as an antioxidant and preservative booster. As a phenol, it is able to neutralize free radicals