Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Dr. Althea 345 Relief Cream Versus Prequel Half & Half Peptides & Ceramides Fluid Moisturizer

Dr. Althea 345 Relief Cream Versus Prequel Half & Half Peptides & Ceramides Fluid Moisturizer Detailed comparison of Dr. Althea 345 Relief Cream versus Prequel Half & Half Peptides & Ceramides Fluid Moisturizer. This calming moisturizer is formulated around Me

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Dr. Althea 345 Relief Cream Versus Prequel Half & Half Peptides & Ceramides Fluid Moisturizer Detailed comparison of Dr. Althea 345 Relief Cream versus Prequel Half & Half Peptides & Ceramides Fluid Moisturizer. This calming moisturizer is formulated around Melaleuca Alternifolia Leaf Water and Niacinamide to calm redness and strengthen the skin barrier. This barrier-repair moisturizer is formulated around Ceramide NP and Hexapeptide-11 to strengthen the skin barrier and soften the look of wrinkles. No concerns Water Melaleuca Alternifolia Leaf Water Propanediol Glycerin 1,2-Hexanediol Hydrogenated Polydecene Vinyldimethicone C14-22 Alcohols Niacinamide Caprylic/Capric Triglyceride Panthenol Dicaprylyl Carbonate Butylene Glycol Ammonium Acryloyldimethyltaurate/Vp Copolymer Caprylyl Methicone Polymethylsilsesquioxane C12-20 Alkyl Glucoside Hydroxyacetophenone Acrylates/C10-30 Alkyl Acrylate Crosspolymer Polyquaternium-51 Ethylhexylglycerin Tromethamine Sodium Hyaluronate Sodium Stearoyl Glutamate Coptis Japonica Root Extract Centella Asiatica Leaf Water Beta-Glucan Resveratrol Hydrolyzed Hyaluronic Acid Camellia Sinensis Leaf Water Tocopherol Madecassoside Sodium DNA Centella Asiatica Extract Ceramide NP Tannic Acid Disodium EDTA Sodium Phytate Water, Melaleuca Alternifolia Leaf Water, Propanediol, Glycerin, 1,2-Hexanediol, Hydrogenated Polydecene, Vinyldimethicone, C14-22 Alcohols, Niacinamide, Caprylic/Capric Triglyceride, Panthenol, Dicaprylyl Carbonate, Butylene Glycol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Caprylyl Methicone, Polymethylsilsesquioxane, C12-20 Alkyl Glucoside, Hydroxyacetophenone, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Polyquaternium-51, Ethylhexylglycerin, Tromethamine, Sodium Hyaluronate, Sodium Stearoyl Glutamate, Coptis Japonica Root Extract, Centella Asiatica Leaf Water, Beta-Glucan, Resveratrol, Hydrolyzed Hyaluronic Acid, Camellia Sinensis Leaf Water, Tocopherol, Madecassoside, Sodium DNA, Centella Asiatica Extract, Ceramide NP, Tannic Acid, Disodium EDTA, Sodium Phytate Isopropyl Myristate Ethylhexyl Olivate Squalane Hydrolyzed Rice Protein Ceramide As Ceramide Ns Ceramide EOP Ceramide AP Hexapeptide-11 Matrixyl 3000 Polyglyceryl-10 Stearate Triolein Glyceryl Oleate Undecane Glyceryl Dioleate Caprylyl Glycol Xanthan Gum Tridecane Betaine Citric Acid Sodium PCA Sodium Hydroxide Sodium Lactate PCA Sodium Benzoate Serine Alanine Palmitic Acid Glycine Hydrogenated Lecithin Ethylhexyl Palmitate Phenoxyethanol Glutamic Acid Lysine Hcl Threonine Arginine Proline Carbomer Polysorbate 20 Water, Glycerin, Propanediol, Isopropyl Myristate, Ethylhexyl Olivate, Squalane, Hydrolyzed Rice Protein, Ceramide NP, Ceramide As, Ceramide Ns, Ceramide EOP, Ceramide AP, Hexapeptide-11, Matrixyl 3000, Polyglyceryl-10 Stearate, Triolein, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Glyceryl Oleate, Undecane, Hydroxyacetophenone, Glyceryl Dioleate, Caprylyl Glycol, Xanthan Gum, Tridecane, Betaine, Sodium Stearoyl Glutamate, Citric Acid, Sodium Phytate, Sodium PCA, Sodium Hydroxide, Sodium Lactate, PCA, Sodium Benzoate, Serine, Alanine, Palmitic Acid, Glycine, Hydrogenated Lecithin, Ethylhexyl Palmitate, Butylene Glycol, Phenoxyethanol, Ethylhexylglycerin, Glutamic Acid, Lysine Hcl, Threonine, Arginine, Proline, Tocopherol, Carbomer, Polysorbate 20 These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Ammonium Acryloyldimethyltaurate/Vp Copolymer is a synthetically created polymer. It's used as a film-forming agent and used to thicken the consistency of products. Think of it as a supportive ingredient that helps your gel-creams feel silky, "cloud cream-like", and spread evenly without being greasy. The Cosmetic Ingredient Review (CIR) Expert Panel evaluated it (along with 22 other acryloyldimethyltaurate polymers) and concluded it's: Due to its large molecular size, it sits on the surface of skin rather than penetrating it. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids. Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes. This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants. A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%. Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days. Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient. Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically. Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that: The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure. Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic