Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Dr. Reju-All Advanced PDRN Copper Peptide Serum Versus Numbuzin 9+ NAD Bio Lifting-Sil Essence

Dr. Reju-All Advanced PDRN Copper Peptide Serum Versus Numbuzin 9+ NAD Bio Lifting-Sil Essence Detailed comparison of Dr. Reju-All Advanced PDRN Copper Peptide Serum versus Numbuzin 9+ NAD Bio Lifting-Sil Essence. This anti-aging serum is formulated around Nia

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Dr. Reju-All Advanced PDRN Copper Peptide Serum Versus Numbuzin 9+ NAD Bio Lifting-Sil Essence Detailed comparison of Dr. Reju-All Advanced PDRN Copper Peptide Serum versus Numbuzin 9+ NAD Bio Lifting-Sil Essence. This anti-aging serum is formulated around Niacinamide and Sodium DNA to soften the look of wrinkles and strengthen the skin barrier. This anti-aging essence is formulated around Niacinamide and Adenosine to soften the look of wrinkles and refine skin texture. Water Butylene Glycol Glycerin Dipropylene Glycol 1,2-Hexanediol Isopentyldiol Niacinamide Caprylic/Capric Triglyceride Sodium DNA Copper Tripeptide-1 Acetyl Octapeptide-3 Acetyl Tetrapeptide-5 Acetyl Tetrapeptide-9 Palmitoyl Hexapeptide-12 Palmitoyl Tripeptide-5 Sodium Hyaluronate Hydrolyzed Collagen Chamaecyparis Obtusa Oil Anthemis Nobilis Flower Oil Guaiazulene Panthenol Sorbitol C12-14 Alketh-12 Sodium Polyacryloyldimethyl Taurate Acrylates/C10-30 Alkyl Acrylate Crosspolymer Propanediol Tromethamine Ethylhexylglycerin Allantoin Sodium PCA Adenosine Gellan Gum Glyceryl Acrylate/Acrylic Acid Copolymer Agar Sodium Phytate Beta-Glucan Tocopherol Xanthan Gum Water, Butylene Glycol, Glycerin, Dipropylene Glycol, 1,2-Hexanediol, Isopentyldiol, Niacinamide, Caprylic/Capric Triglyceride, Sodium DNA, Copper Tripeptide-1, Acetyl Octapeptide-3, Acetyl Tetrapeptide-5, Acetyl Tetrapeptide-9, Palmitoyl Hexapeptide-12, Palmitoyl Tripeptide-5, Sodium Hyaluronate, Hydrolyzed Collagen, Chamaecyparis Obtusa Oil, Anthemis Nobilis Flower Oil, Guaiazulene, Panthenol, Sorbitol, C12-14 Alketh-12, Sodium Polyacryloyldimethyl Taurate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Propanediol, Tromethamine, Ethylhexylglycerin, Allantoin, Sodium PCA, Adenosine, Gellan Gum, Glyceryl Acrylate/Acrylic Acid Copolymer, Agar, Sodium Phytate, Beta-Glucan, Tocopherol, Xanthan Gum Hydrogenated Poly(C6-14 Olefin) Polyglycerin-3 Pentaerythrityl Tetraethylhexanoate Dimethicone Methylpropanediol Cetearyl Alcohol Glyceryl Stearate Hydrogenated Vegetable Oil Polyglyceryl-3 Methylglucose Distearate Butyrospermum Parkii Butter Dimethicone Crosspolymer Ammonium Acryloyldimethyltaurate/Vp Copolymer Sodium Polyacrylate Hydrogenated Lecithin Carbomer Pentylene Glycol Palmitic Acid Stearic Acid Cholesterol Adenosine Triphosphate Hydroxypropyl Cyclodextrin Nicotinamide Adenine Dinucleotide Copper Gluconate Saccharomyces/Copper Ferment Saccharomyces/Iron Ferment Saccharomyces/Magnesium Ferment Saccharomyces/Silicon Ferment Saccharomyces/Zinc Ferment Capryloyl Dipeptide-17 Thioctic Acid Leuconostoc/Radish Root Ferment Filtrate Glutathione Tremella Fuciformis Extract Haematococcus Pluvialis Oil Potassium Hydroxide Resveratrol Hesperidin Methyl Chalcone Sorbitan Laurate Steareth-20 Astaxanthin Sodium Lactate Hydroxyethylcellulose Acetyl Dipeptide-1 Cetyl Ester Dipeptide Diaminobutyroyl Benzylamide Diacetate Heptasodium Hexacarboxymethyl Dipeptide-12 Polysorbate 20 Sodium Citrate Chlorhexidine Digluconate Dextran Hexapeptide-2 Magnesium Chloride Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate Dipeptide-2 Potassium Sorbate Acetyl Hexapeptide-8 Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine Citric Acid Biotin Palmitoyl Tetrapeptide-7 Biotinoyl Tripeptide-1 Acetyl Tetrapeptide-3 Trifolium Pratense Flower Extract Tocopheryl Acetate Palmitoyl Tripeptide-8 Dipeptide-4 Hexapeptide-11 Pentapeptide-18 Tripeptide-3 Sh-Decapeptide-7 Sh-Octapeptide-4 Palmitoyl Tripeptide-1 Ascorbic Aci These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. 1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. It is a: Humectant, drawing moisture into the skin Emollient, helping to soften skin Solvent, dispersing and stabilizing formulas Preservative booster, enhancing the antimicrobial activity of other preservatives Acetyl Octapeptide-3 is a synthetic peptide also commonly known as SNAP-8. It is a lab-made peptide often marketed as a gentler, topical alternative to Botox. It works by mimicking part of a protein involved in muscle contractions, which may help relax facial tension and reduce the appearance of fine lines (mostly around the eyes and forehead). It’s considered a “next-gen” version of Argireline (Acetyl Hexapeptide-8), an older peptide with more research behind it that also supports collagen production. SNAP-8 showed slightly better results than Argireline in one small manufacturer-funded study, but there’s limited independent research. Plus, most tests use concentrations higher than what’s typically found in skincare products. This ingredient might offer a subtle smoothing effect but it won't don’t deliver the dramatic results of actual Botox injections. Think of it more like a supporting actor in your skincare lineup. Acetyl Tetrapeptide-5 is a peptide that goes by another name, eyeseryl, due to claims that it can help reduce eye puffiness. The manufacturer claims this ingredient reduces eye puffiness by: An in-vivo study from the manufacturer found 95% of volunteers saw eye bag improvement by the end of the study. Eye puffiness is caused by two major factors: fluid retention and fat. Those with fluid retention may see improvement from using this ingredient. However, those with eye fat will need surgical intervention in order to get rid of puffiness. Acetyl Tetrapeptide-9 is a signal peptide. Signal peptides tell your skin to create collagen or start tissue repair. This peptide plays a role in key skin components such as collagen, lumican, and glycosaminoglycans (GAGs). Lumican is used in collagen organization and regulation, while GAGs are a component that holds water in our skin. The manufacturer claims this ingredient is effective at firming the skin and enhancing skin hydration. Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent. The way it works is fairly well mapped out: Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going. The clinical backing is pretty solid too. A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream t