Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

DRMTLGY Needle-Less Serum Versus Origins Plantscription Multi-Powered Youth Serum

DRMTLGY Needle-Less Serum Versus Origins Plantscription Multi-Powered Youth Serum Detailed comparison of DRMTLGY Needle-Less Serum versus Origins Plantscription Multi-Powered Youth Serum. This anti-aging serum is formulated around Palmitoyl Tripeptide-1 and Pa

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DRMTLGY Needle-Less Serum Versus Origins Plantscription Multi-Powered Youth Serum Detailed comparison of DRMTLGY Needle-Less Serum versus Origins Plantscription Multi-Powered Youth Serum. This anti-aging serum is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles. This anti-aging serum is formulated around Niacinamide and Acetyl Hexapeptide-8 to soften the look of wrinkles and refine skin texture. Water Glycerin Sodium Chondroitin Sulfate Sodium Hyaluronate Pisum Sativum Extract Bambusa Vulgaris Leaf/Stem Extract Palmitoyl Tripeptide-1 Palmitoyl Tetrapeptide-7 Ceramide EOP Glucosamine Hcl Glycosaminoglycans Ceramide NP Palmitoyl Tripeptide-5 Ceramide AP Phytosphingosine Cholesterol Niacinamide Sodium Lauroyl Lactylate Methylglucoside Phosphate Copper Lysinate/Prolinate Panthenol Tocopheryl Acetate Phenoxyethanol Polysorbate 20 Ethylhexylglycerin Disodium EDTA Butylene Glycol Carbomer Xanthan Gum Water, Glycerin, Sodium Chondroitin Sulfate, Sodium Hyaluronate, Pisum Sativum Extract, Bambusa Vulgaris Leaf/Stem Extract, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide EOP, Glucosamine Hcl, Glycosaminoglycans, Ceramide NP, Palmitoyl Tripeptide-5, Ceramide AP, Phytosphingosine, Cholesterol, Niacinamide, Sodium Lauroyl Lactylate, Methylglucoside Phosphate, Copper Lysinate/Prolinate, Panthenol, Tocopheryl Acetate, Phenoxyethanol, Polysorbate 20, Ethylhexylglycerin, Disodium EDTA, Butylene Glycol, Carbomer, Xanthan Gum Heptyl Undecylenate Octyldodecanol Glycereth-26 Sodium Acrylates Copolymer Algae Extract Illicium Verum Fruit/Seed Oil Citrus Aurantium Bergamia Fruit Oil Pelargonium Graveolens Flower Oil Lavandula Angustifolia Oil Citrus Limon Peel Oil Litsea Cubeba Fruit Oil Citrus Nobilis Peel Oil Myristica Fragrans Kernel Oil Citrus Aurantium Dulcis Oil Rosa Damascena Flower Oil Hibiscus Abelmoschus Extract Carthamus Tinctorius Seed Oil Linalool Geraniol Citronellol Limonene Anogeissus Leiocarpus Bark Extract Acetyl Hexapeptide-8 Acetyl Octapeptide-3 Palmitoyl Hexapeptide-12 Dipeptide Diaminobutyroyl Benzylamide Diacetate Sigesbeckia Orientalis Extract Commiphora Mukul Resin Extract Laminaria Saccharina Extract Bambusa Vulgaris Extract Caffeine Rosmarinus Officinalis Leaf Extract Molasses Extract Scutellaria Baicalensis Root Extract Pyrus Malus Fruit Extract Cucumis Sativus Fruit Extract Caprylic/Capric Triglyceride Lecithin Caprylyl Glycol Hexylene Glycol PEG-8 Glyceryl Polymethacrylate Sodium Metabisulfite Sodium Sulfite Sodium Phytate BHT Potassium Sorbate Water, Butylene Glycol, Niacinamide, Glycerin, Heptyl Undecylenate, Octyldodecanol, Glycereth-26, Sodium Acrylates Copolymer, Algae Extract, Illicium Verum Fruit/Seed Oil, Citrus Aurantium Bergamia Fruit Oil, Pelargonium Graveolens Flower Oil, Lavandula Angustifolia Oil, Citrus Limon Peel Oil, Litsea Cubeba Fruit Oil, Citrus Nobilis Peel Oil, Myristica Fragrans Kernel Oil, Citrus Aurantium Dulcis Oil, Rosa Damascena Flower Oil, Hibiscus Abelmoschus Extract, Carthamus Tinctorius Seed Oil, Linalool, Geraniol, Citronellol, Limonene, Anogeissus Leiocarpus Bark Extract, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Acetyl Octapeptide-3, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Sodium Hyaluronate, Sigesbeckia Orientalis Extract, Commiphora Mukul Resin Extract, Laminaria Saccharina Extract, Glucosamine Hcl, Bambusa Vulgaris Ext Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air. This ingredient mainly works behind the scenes and helps with: On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it. One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin). Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption. You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%. We don't have a description for Glucosamine Hcl yet. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British Eng