Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

DRMTLGY Peptide Night Cream Versus Dr. Idriss Major Fade Active Seal Moisturizer

DRMTLGY Peptide Night Cream Versus Dr. Idriss Major Fade Active Seal Moisturizer Detailed comparison of DRMTLGY Peptide Night Cream versus Dr. Idriss Major Fade Active Seal Moisturizer. This anti-aging night moisturizer is formulated around Palmitoyl Tripeptid

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DRMTLGY Peptide Night Cream Versus Dr. Idriss Major Fade Active Seal Moisturizer Detailed comparison of DRMTLGY Peptide Night Cream versus Dr. Idriss Major Fade Active Seal Moisturizer. This anti-aging night moisturizer is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tripeptide-5 to soften the look of wrinkles. This brightening moisturizer is formulated around Tetrahexyldecyl Ascorbate and 4-Butylresorcinol to fade the look of dark spots and brighten dull-looking skin. Water Glyceryl Stearate Propanediol C12-15 Alkyl Benzoate Glycerin Isopropyl Palmitate Undecane Butyrospermum Parkii Butter Caprylic/Capric Triglyceride Cetyl Alcohol Dimethicone PEG-100 Stearate Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine Palmitoyl Tripeptide-1 Palmitoyl Tripeptide-5 Palmitoyl Tetrapeptide-7 Trifluoroacetyl Tripeptide-2 Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate Ceramide NP Ceramide AP Ceramide EOP Phytosphingosine Cholesterol Tridecane Allantoin Tocopherol Glycol Distearate Potassium Cetyl Phosphate Butylene Glycol Ethylhexylglycerin Acrylates/C10-30 Alkyl Acrylate Crosspolymer Carbomer Polysorbate 20 Dextran Magnesium Chloride Phenoxyethanol Disodium EDTA Sodium Hydroxide Sodium Lauroyl Lactylate Xanthan Gum Water, Glyceryl Stearate, Propanediol, C12-15 Alkyl Benzoate, Glycerin, Isopropyl Palmitate, Undecane, Butyrospermum Parkii Butter, Caprylic/Capric Triglyceride, Cetyl Alcohol, Dimethicone, PEG-100 Stearate, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Palmitoyl Tetrapeptide-7, Trifluoroacetyl Tripeptide-2, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Ceramide NP, Ceramide AP, Ceramide EOP, Phytosphingosine, Cholesterol, Tridecane, Allantoin, Tocopherol, Glycol Distearate, Potassium Cetyl Phosphate, Butylene Glycol, Ethylhexylglycerin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Carbomer, Polysorbate 20, Dextran, Magnesium Chloride, Phenoxyethanol, Disodium EDTA, Sodium Hydroxide, Sodium Lauroyl Lactylate, Xanthan Gum Tetrahexyldecyl Ascorbate Squalane Bis-PEG-18 Methyl Ether Dimethyl Silane Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Triheptanoin Pentylene Glycol Phenyl Trimethicone Oxidized Glutathione 4-Butylresorcinol Hexapeptide-2 Hydrolyzed Brassica Napus Seedcake Extract Cetearyl Olivate Coco-Caprylate/Caprate Sorbitan Olivate Polysorbate 60 Dilinoleic Acid/Butanediol Copolymer Dipotassium Glycyrrhizate Tetrasodium Glutamate Diacetate Sorbitan Isostearate Castor Oil/Ipdi Copolymer Sodium Benzoate Potassium Sorbate Water, Glycerin, Tetrahexyldecyl Ascorbate, Squalane, Caprylic/Capric Triglyceride, Bis-PEG-18 Methyl Ether Dimethyl Silane, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Triheptanoin, Pentylene Glycol, Phenyl Trimethicone, Oxidized Glutathione, 4-Butylresorcinol, Hexapeptide-2, Hydrolyzed Brassica Napus Seedcake Extract, Ceramide NP, Ceramide AP, Ceramide EOP, Tocopherol, Butylene Glycol, Cetearyl Olivate, Coco-Caprylate/Caprate, Sorbitan Olivate, Ethylhexylglycerin, Polysorbate 60, Xanthan Gum, Dilinoleic Acid/Butanediol Copolymer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Cholesterol, Phytosphingosine, Dipotassium Glycyrrhizate, Sodium Lauroyl Lactylate, Carbomer, Sodium Hydroxide, Tetrasodium Glutamate Diacetate, Sorbitan Isostearate, Castor Oil/Ipdi Copolymer, Sodium Benzoate, Potassium Sorbate, Phenoxyethanol Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products. As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied. It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin. A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss. Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid. In practice, that translates to a long shelf life and a consistently elegant skin feel. While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns. Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source. This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out. This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%. Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true