Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Drunk Elephant A-Passioni Retinol Cream Versus Paula's Choice Resist Barrier Repair Moisturizer with Retinol

Drunk Elephant A-Passioni Retinol Cream Versus Paula's Choice Resist Barrier Repair Moisturizer with Retinol Detailed comparison of Drunk Elephant A-Passioni Retinol Cream versus Paula's Choice Resist Barrier Repair Moisturizer with Retinol. This anti-aging tr

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Drunk Elephant A-Passioni Retinol Cream Versus Paula's Choice Resist Barrier Repair Moisturizer with Retinol Detailed comparison of Drunk Elephant A-Passioni Retinol Cream versus Paula's Choice Resist Barrier Repair Moisturizer with Retinol. This anti-aging treatment is formulated around Retinol and Niacinamide to soften the look of wrinkles and refine skin texture. This barrier-repair moisturizer is formulated around Retinol and Ceramide NP to strengthen the skin barrier and soften the look of wrinkles. Water Glycerin Coco-Caprylate Stearic Acid Coconut Alkanes Glyceryl Stearate Niacinamide Caprylic/Capric Triglyceride Cetearyl Alcohol Pentylene Glycol Passiflora Edulis Seed Oil Retinol Simmondsia Chinensis Seed Oil Sclerocarya Birrea Seed Oil Prunus Armeniaca Kernel Oil Cetyl Ethylhexanoate Palmitoyl Tripeptide-1 Palmitoyl Tetrapeptide-7 Brassica Oleracea Acephala Leaf Extract Brassica Oleracea Italica Extract Tetrahexyldecyl Ascorbate Chrysin Persea Gratissima Oil Linoleic Acid Linolenic Acid Ceramide NP Xanthophylls Phytosphingosine Phytosterols Jojoba Esters Physalis Pubescens Fruit Juice Stearyl Glycyrrhetinate Oryza Sativa Extract Glycine Soja Oil Carthamus Tinctorius Seed Oil Palmitoyl Hexapeptide-12 Cetyl Palmitate Trehalose Lauric Acid Sodium Hyaluronate Crosspolymer Olea Europaea Fruit Oil Glucosamine Hcl Tocopheryl Acetate Coco-Caprylate/Caprate Pisum Sativum Extract Tocopherol Bambusa Vulgaris Leaf/Stem Extract Phenoxyethanol Caprylyl Glycol Carbomer Trideceth-6 Phosphate N-Hydroxysuccinimide Ceteareth-20 Sodium Hydroxide Laureth-23 Steareth-20 Propanediol Chlorhexidine Digluconate Polysorbate 20 Trisodium Ethylenediamine Disuccinate Chlorphenesin Potassium Sorbate Ethylhexylglycerin Water, Glycerin, Coco-Caprylate, Stearic Acid, Coconut Alkanes, Glyceryl Stearate, Niacinamide, Caprylic/Capric Triglyceride, Cetearyl Alcohol, Pentylene Glycol, Passiflora Edulis Seed Oil, Retinol, Simmondsia Chinensis Seed Oil, Sclerocarya Birrea Seed Oil, Prunus Armeniaca Kernel Oil, Cetyl Ethylhexanoate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Brassica Oleracea Acephala Leaf Extract, Brassica Oleracea Italica Extract, Tetrahexyldecyl Ascorbate, Chrysin, Persea Gratissima Oil, Linoleic Acid, Linolenic Acid, Ceramide NP, Xanthophylls, Phytosphingosine, Phytosterols, Jojoba Esters, Physalis Pubescens Fruit Juice, Stearyl Glycyrrhetinate, Oryza Sativa Extract, Glycine Soja Oil, Carthamus Tinctorius Seed Oil, Palmitoyl Hexapeptide-12, Cetyl Palmitate, Trehalose, Lauric Acid, Sodium Hyaluronate Crosspolymer, Olea Europaea Fruit Oil, Glucosamine Hcl, Tocopheryl Acetate, Coco-Caprylate/Caprate, Pisum Sativum Extract, Tocopherol, Bambusa Vulgaris Leaf/Stem Extract, Phenoxyethanol, Caprylyl Glycol, Carbomer, Trideceth-6 Phosphate, N-Hydroxysuccinimide, Ceteareth-20, Sodium Hydroxide, Laureth-23, Steareth-20, Propanediol, Chlorhexidine Digluconate, Polysorbate 20, Trisodium Ethylenediamine Disuccinate, Chlorphenesin, Potassium Sorbate, Ethylhexylglycerin Dicaprylyl Carbonate Ethylhexyl Stearate Cocoglycerides Butyrospermum Parkii Butter Squalane Sodium Polyacrylate Lecithin Adenosine Punica Granatum Extract Camellia Oleifera Leaf Extract Glycyrrhiza Glabra Root Extract Tetrahydrodiferuloylmethane Tetrahydrodemethoxydiferuloylmethane Tetrahydrobisdemethoxydiferuloylmethane Chamomilla Recutita Flower Extract Glycine Soja Seed Extract Butylene Glycol Propylene Glycol Glyceryl Polymethacrylate Xanthan Gum Water, Dicaprylyl Carbonate, Glycerin, Ethylhexyl Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids. Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes. This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants. A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%. Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days. Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient. Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Glycine Soja Oil is a plant-derived oil from soybean seeds. Like other oils, it is rich in essential fatty acids (mostly linoleic and oleic) that support skin hydration and barrier function. The fatty acids are able to integrate into the lipid matrix of the stratum corneum to help soften skin and reduce water loss. On top of that, soybean oil is rich in vitamins like vitamin E, a potent antioxidant. Research on soybean's active components also point to anti-inflammatory, collagen-stimulating, antioxidant activity, and protection against UV-induced oxidative damage. Most of this research applies to the broader soybean plant and not just the oil fraction alone. This ingredient may not be fungal acne safe due to the oleic acid content. Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid. That fatty acid attachment is the key: it boosts the peptide's ab