Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Drunk Elephant Protini Polypeptide Cream Versus La Roche-Posay Hyalu B5 Cream

Drunk Elephant Protini Polypeptide Cream Versus La Roche-Posay Hyalu B5 Cream Detailed comparison of Drunk Elephant Protini Polypeptide Cream versus La Roche-Posay Hyalu B5 Cream Canada. This anti-aging moisturizer is formulated around Sclerocarya Birrea Seed

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Drunk Elephant Protini Polypeptide Cream Versus La Roche-Posay Hyalu B5 Cream Detailed comparison of Drunk Elephant Protini Polypeptide Cream versus La Roche-Posay Hyalu B5 Cream Canada. This anti-aging moisturizer is formulated around Sclerocarya Birrea Seed Oil and Sh-Oligopeptide-1 to soften the look of wrinkles and hydrate skin. This anti-aging moisturizer is formulated around Panthenol and Sodium Hyaluronate to soften the look of wrinkles and hydrate skin. Water Dicaprylyl Carbonate Glycerin Cetearyl Alcohol Cetearyl Olivate Sorbitan Olivate Sclerocarya Birrea Seed Oil Bacillus/Folic Acid Ferment Filtrate Extract Nymphaea Alba Root Extract Sh-Oligopeptide-1 Sh-Oligopeptide-2 Sh-Polypeptide-1 Sh-Polypeptide-9 Sh-Polypeptide-11 Copper Palmitoyl Heptapeptide-14 Heptapeptide-15 Palmitate Palmitoyl Tetrapeptide-7 Palmitoyl Tripeptide-1 Alanine Arginine Glycine Histidine Isoleucine Phenylalanine Proline Serine Threonine Valine Acetyl Glutamine Coconut Alkanes Coco-Caprylate/Caprate Sodium Hyaluronate Aspartic Acid Linoleic Acid Linolenic Acid Lecithin Butylene Glycol Polyvinyl Alcohol Sodium Lactate Sodium PCA PCA Sorbitan Isostearate Carbomer Polysorbate 20 Polysorbate 60 Lactic Acid/Glycolic Acid Copolymer Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Xanthan Gum Isomalt 1,2-Hexanediol Caprylyl Glycol Chlorphenesin Phenoxyethanol Tocopherol Sodium Benzoate Phenylpropanol Glyceryl Caprylate Symphytum Officinale Callus Culture Extract Water, Dicaprylyl Carbonate, Glycerin, Cetearyl Alcohol, Cetearyl Olivate, Sorbitan Olivate, Sclerocarya Birrea Seed Oil, Bacillus/Folic Acid Ferment Filtrate Extract, Nymphaea Alba Root Extract, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Alanine, Arginine, Glycine, Histidine, Isoleucine, Phenylalanine, Proline, Serine, Threonine, Valine, Acetyl Glutamine, Coconut Alkanes, Coco-Caprylate/Caprate, Sodium Hyaluronate, Aspartic Acid, Linoleic Acid, Linolenic Acid, Lecithin, Butylene Glycol, Polyvinyl Alcohol, Sodium Lactate, Sodium PCA, PCA, Sorbitan Isostearate, Carbomer, Polysorbate 20, Polysorbate 60, Lactic Acid/Glycolic Acid Copolymer, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Xanthan Gum, Isomalt, 1,2-Hexanediol, Caprylyl Glycol, Chlorphenesin, Phenoxyethanol, Tocopherol, Sodium Benzoate, Phenylpropanol, Glyceryl Caprylate, Symphytum Officinale Callus Culture Extract Dimethicone Hydrogenated Polyisobutene Propylene Glycol Hydroxypropyl Tetrahydropyrantriol Alcohol Denat. Propanediol Panthenol Synthetic Wax Nylon-12 PEG-10 Dimethicone Dimethicone/PEG-10/15 Crosspolymer Hydroxyethylpiperazine Ethane Sulfonic Acid Sodium Polyacrylate Hydrolyzed Hyaluronic Acid Sodium Citrate Adenosine Propylene Carbonate Dipropylene Glycol Disteardimonium Hectorite Disodium EDTA Parfum Water, Glycerin, Dimethicone, Hydrogenated Polyisobutene, Propylene Glycol, Hydroxypropyl Tetrahydropyrantriol, Alcohol Denat., Propanediol, Panthenol, Synthetic Wax, Nylon-12, PEG-10 Dimethicone, Dimethicone/PEG-10/15 Crosspolymer, Hydroxyethylpiperazine Ethane Sulfonic Acid, Tocopherol, Sodium Polyacrylate, Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Citrate, Phenoxyethanol, Adenosine, Chlorphenesin, Propylene Carbonate, Dipropylene Glycol, Disteardimonium Hectorite, Disodium EDTA, Parfum These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Chlorphenesin is a synthetic preservative. It helps protect a product against bacteria in order to extend shelf life. In most cases, Chlorphenesin is paired with other preservatives such as phenoxyethanol and caprylyl glycol. Chlorphenesin is a biocide. This means it is able to help fight the microorganisms on our skin. It is also able to fight odor-releasing bacteria. Chlorphenesin is soluble in both water and glycerin. Studies show Chlorphenesin is easily absorbed by our skin. You should speak with a skincare professional if you have concerns about using Chlorphenesin. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive. Another perk of this ingredient is that it stays functional across a wide pH range (3-10). You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own. Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU. Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages. Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon