Peptide Skincare & BeautySkin science and ingredient guides

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epi.logic The Total Package Fortifying Peptide Cream Versus ROSE Ingleton MD Signature Moisturizer

epi.logic The Total Package Fortifying Peptide Cream Versus ROSE Ingleton MD Signature Moisturizer Detailed comparison of epi.logic The Total Package Fortifying Peptide Cream versus ROSE Ingleton MD Signature Moisturizer. This barrier-repair moisturizer is for

This source-based comparison does not add ratings or recommend a winner.

epi.logic The Total Package Fortifying Peptide Cream Versus ROSE Ingleton MD Signature Moisturizer Detailed comparison of epi.logic The Total Package Fortifying Peptide Cream versus ROSE Ingleton MD Signature Moisturizer. This barrier-repair moisturizer is formulated around Niacinamide and Palmitoyl Tripeptide-38 to strengthen the skin barrier and soften the look of wrinkles. This barrier-repair moisturizer is formulated around Niacinamide and Ceramide NP to strengthen the skin barrier and soften the look of wrinkles. Water Glycerin C13-15 Alkane Squalane Octyldodecanol Niacinamide Polyglyceryl-4 Oleate Butyrospermum Parkii Butter Caprylic/Capric Triglyceride Magnesium Sulfate Polyglyceryl-6 Oleate Polyhydroxystearic Acid Sodium Hyaluronate Palmitoyl Tripeptide-38 Sh-Polypeptide-121 Laminaria Digitata Extract Ceramide NP Gluconolactone Disteardimonium Hectorite Bakuchiol Propylene Carbonate Silybum Marianum Seed Extract Artemisia Capillaris Flower Extract Triolein Glyceryl Dioleate Sodium PCA Sodium Lactate Calcium Gluconate Hydroxypropyl Cyclodextrin Arginine Aspartic Acid PCA Glycine Alanine Tocopherol Serine Valine Isoleucine Proline Threonine Histidine Phenylalanine Ubiquinone Superoxide Dismutase Propanediol Xanthan Gum Salvia Hispanica Seed Oil Boswellia Carterii Resin Extract Lactic Acid Potassium Sorbate Sodium Benzoate Water, Glycerin, C13-15 Alkane, Squalane, Octyldodecanol, Niacinamide, Polyglyceryl-4 Oleate, Butyrospermum Parkii Butter, Caprylic/Capric Triglyceride, Magnesium Sulfate, Polyglyceryl-6 Oleate, Polyhydroxystearic Acid, Sodium Hyaluronate, Palmitoyl Tripeptide-38, Sh-Polypeptide-121, Laminaria Digitata Extract, Ceramide NP, Gluconolactone, Disteardimonium Hectorite, Bakuchiol, Propylene Carbonate, Silybum Marianum Seed Extract, Artemisia Capillaris Flower Extract, Triolein, Glyceryl Dioleate, Sodium PCA, Sodium Lactate, Calcium Gluconate, Hydroxypropyl Cyclodextrin, Arginine, Aspartic Acid, PCA, Glycine, Alanine, Tocopherol, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Ubiquinone, Superoxide Dismutase, Propanediol, Xanthan Gum, Salvia Hispanica Seed Oil, Boswellia Carterii Resin Extract, Lactic Acid, Potassium Sorbate, Sodium Benzoate Dimethicone Pentylene Glycol Castanea Sativa Seed Extract Cetearyl Alcohol Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Sorbitan Stearate Ascorbyl Glucoside Ceramide AP Ceramide EOP Trehalose Palmitoyl Tripeptide-1 Palmitoyl Tetrapeptide-7 Cucumis Sativus Fruit Extract Vaccinium Myrtillus Fruit Extract Saccharum Officinarum Extract Acer Saccharum Extract Citrus Aurantium Dulcis Fruit Extract Citrus Limon Fruit Extract Glycolic Acid Citric Acid Malic Acid Tartaric Acid Glyceryl Stearate PEG-100 Stearate Tocopheryl Acetate Butylene Glycol Phytosphingosine Cholesterol Sodium Lauroyl Lactylate Sodium Citrate Carbomer Polysorbate 20 Mica Titanium Dioxide CI 77491 Tetrasodium Glutamate Diacetate Sodium Hydroxide Phenoxyethanol Ethylhexylglycerin Water, Dimethicone, Caprylic/Capric Triglyceride, Glycerin, Butyrospermum Parkii Butter, Niacinamide, Pentylene Glycol, Castanea Sativa Seed Extract, Cetearyl Alcohol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Sorbitan Stearate, Ascorbyl Glucoside, Sodium Hyaluronate, Ceramide NP, Ceramide AP, Ceramide EOP, Trehalose, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Cucumis Sativus Fruit Extract, Vaccinium Myrtillus Fruit Extract, Saccharum Officinarum Extract, Acer Saccharum Extract, Citrus Aurantiu Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. This ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients. Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL). In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!). Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo. Shea butter also contains vitamins A and E which may contribute to antioxidant activity. While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement. This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize. Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss. Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid. In practice, that translates to a long shelf life and a consistently elegant skin feel. While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns. Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source. This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out. This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%. Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids. Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes. This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants. A study with 312 p