Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Estée Lauder NightWear Plus Moisturizer Anti-Oxidant Night Detox Creme Versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer

Estée Lauder NightWear Plus Moisturizer Anti-Oxidant Night Detox Creme Versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer Detailed comparison of Estée Lauder NightWear Plus Moisturizer Anti-Oxidant Night Detox Creme versus Olay Regenerist Retinol 24

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Estée Lauder NightWear Plus Moisturizer Anti-Oxidant Night Detox Creme Versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer Detailed comparison of Estée Lauder NightWear Plus Moisturizer Anti-Oxidant Night Detox Creme versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer. This barrier-repair night moisturizer is formulated around Squalane and Ethylbisiminomethylguaiacol Manganese Chloride to strengthen the skin barrier and hydrate skin. This anti-aging night moisturizer is formulated around Retinol and Niacinamide to soften the look of wrinkles and refine skin texture. Water Dimethicone Glycerin Polysorbate 60 Butyrospermum Parkii Butter Hydrogenated Polydecene Propanediol Squalane Sorbitan Stearate Cetyl Palmitate Tridecyl Stearate Laminaria Saccharina Extract Laminaria Ochroleuca Extract Gentiana Lutea Root Extract Hydrolyzed Rice Bran Extract Citrus Reticulata Peel Extract Psidium Guajava Fruit Extract Hydrolyzed Rice Extract Citrus Limon Fruit Extract Fumaria Officinalis Flower/Leaf/Stem Extract Triticum Vulgare Germ Extract Hordeum Vulgare Extract Polygonum Cuspidatum Root Extract Thermus Thermophillus Ferment Coffea Arabica Seed Extract Vitis Vinifera Seed Extract Saccharomyces Lysate Extract Limonium Vulgare Flower/Leaf/Stem Extract Ethylbisiminomethylguaiacol Manganese Chloride Palmitoyl Hydroxypropyltrimonium Amylopectin/Glycerin Crosspolymer Artemia Extract Cholesterol Algae Extract Linoleic Acid Dimethiconol Isohexadecane Sodium Hyaluronate Lecithin Tridecyl Trimellitate Lauryl Alcohol Glycyrrhetinic Acid Trehalose Sucrose Ergothioneine Acrylates/C10-30 Alkyl Acrylate Crosspolymer Dipentaerythrityl Hexacaprylate/Hexacaprate Acetyl Glucosamine Ethylhexylglycerin Butylene Glycol Glyceryl Stearate Behenyl Alcohol Caffeine Palmitic Acid Sodium PCA Stearic Acid Urea Caprylic/Capric Triglyceride Acrylamide/Sodium Acryloyldimethyltaurate Copolymer Tocopheryl Acetate Tetrahexyldecyl Ascorbate Cetyl Alcohol Myristyl Alcohol Polyquaternium-51 Citric Acid Sodium Hydroxide Polysorbate 80 Sodium Benzoate Fumaric Acid Cyclodextrin Parfum Disodium EDTA BHT Phenoxyethanol Chlorphenesin Linalool Butylphenyl Methylpropional Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde Benzyl Salicylate CI 42090 CI 19140 Water, Dimethicone, Glycerin, Polysorbate 60, Butyrospermum Parkii Butter, Hydrogenated Polydecene, Propanediol, Squalane, Sorbitan Stearate, Cetyl Palmitate, Tridecyl Stearate, Laminaria Saccharina Extract, Laminaria Ochroleuca Extract, Gentiana Lutea Root Extract, Hydrolyzed Rice Bran Extract, Citrus Reticulata Peel Extract, Psidium Guajava Fruit Extract, Hydrolyzed Rice Extract, Citrus Limon Fruit Extract, Fumaria Officinalis Flower/Leaf/Stem Extract, Triticum Vulgare Germ Extract, Hordeum Vulgare Extract, Polygonum Cuspidatum Root Extract, Thermus Thermophillus Ferment, Coffea Arabica Seed Extract, Vitis Vinifera Seed Extract, Saccharomyces Lysate Extract, Limonium Vulgare Flower/Leaf/Stem Extract, Ethylbisiminomethylguaiacol Manganese Chloride, Palmitoyl Hydroxypropyltrimonium Amylopectin/Glycerin Crosspolymer, Artemia Extract, Cholesterol, Algae Extract, Linoleic Acid, Dimethiconol, Isohexadecane, Sodium Hyaluronate, Lecithin, Tridecyl Trimellitate, Lauryl Alcohol, Glycyrrhetinic Acid, Trehalose, Sucrose, Ergothioneine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Dipentaerythrityl Hexacaprylate/Hexacaprate, Acetyl Glucosamine, Ethylhexylglycerin, Butylene Glycol, Glyceryl Stearate, Behenyl Alcohol, Caffeine, Palmitic Acid, Sodium PCA, Stearic Acid, Urea, Caprylic/Capric Triglyceride, Acrylamide/Sodium Acryloyld These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products. As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied. It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin. A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record. Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss. Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid. In practice, that translates to a long shelf life and a consistently elegant skin feel. While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns. Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source. This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out. This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%. Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane. What it does: Dimethicone comes in different viscosities: Depending on the viscosity, dimethicone has different properties. Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity. This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient. Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy. Dimethiconol is a silicone that resembles the popular dimethicone. Like other silicones, it is an emollient. Emollients create a thin film on skin to prevent moisture from escaping. This ingredi