Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Estée Lauder Perfectionist Pro Rapid Firm + Lift Treatment with Acetyl Hexapeptide-8 Versus DRMTLGY Peptide Night Cream

Estée Lauder Perfectionist Pro Rapid Firm + Lift Treatment with Acetyl Hexapeptide-8 Versus DRMTLGY Peptide Night Cream Detailed comparison of Estée Lauder Perfectionist Pro Rapid Firm + Lift Treatment with Acetyl Hexapeptide-8 versus DRMTLGY Peptide Night Cre

This source-based comparison does not add ratings or recommend a winner.

Estée Lauder Perfectionist Pro Rapid Firm + Lift Treatment with Acetyl Hexapeptide-8 Versus DRMTLGY Peptide Night Cream Detailed comparison of Estée Lauder Perfectionist Pro Rapid Firm + Lift Treatment with Acetyl Hexapeptide-8 versus DRMTLGY Peptide Night Cream. This anti-aging serum is formulated around Acetyl Glucosamine and Acetyl Hexapeptide-8 to soften the look of wrinkles. This anti-aging night moisturizer is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tripeptide-5 to soften the look of wrinkles. Water Dimethicone Butylene Glycol Caprylic/Capric Triglyceride Glycerin Bis-PEG-18 Methyl Ether Dimethyl Silane Polysorbate 20 Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone Polysilicone-11 Mangifera Indica Seed Butter Phoenix Dactylifera Fruit Extract Pisum Sativum Extract Cucumis Sativus Fruit Extract Crithmum Maritimum Extract Laminaria Ochroleuca Extract Commiphora Mukul Resin Extract Triticum Vulgare Germ Extract Bambusa Vulgaris Extract Chlorella Vulgaris Extract Laminaria Saccharina Extract Brassica Campestris Sterols Helianthus Annuus Seed Extract Algae Extract Hypnea Musciformis Extract Sigesbeckia Orientalis Extract Nymphaea Alba Flower Extract Acetyl Glucosamine Caffeine Gelidiella Acerosa Extract Coffea Arabica Seed Extract Sodium Hyaluronate Lactic Acid Propylene Glycol Dicaprate Saccharide Isomerate Methyl Gluceth-20 Ethylhexylglycerin Acrylamide/Sodium Acryloyldimethyltaurate Copolymer Helianthus Annuus Seedcake Caprylyl Glycol Isohexadecane Tocopheryl Acetate Acrylates/C10-30 Alkyl Acrylate Crosspolymer Glyceryl Polymethacrylate Sodium Polyacrylate Starch Squalane Sodium PCA Urea Zea Mays Kernel Extract Whey Protein Palmaria Palmata Extract Polysorbate 80 Acetyl Hexapeptide-8 Triolein Hydrolyzed Rice Extract Linoleic Acid Trehalose Glycine Soja Protein Glucosamine Hcl Phospholipids Laminaria Digitata Extract Hordeum Vulgare Extract Polyquaternium-51 Palmitoyl Hexapeptide-12 Ergothioneine Aminopropyl Ascorbyl Phosphate PEG-8 Phytosteryl Canola Glycerides Pentylene Glycol Oleic Acid Palmitic Acid Xanthan Gum Parfum Sodium Hydroxide Citric Acid Silica Calcium Chloride Stearic Acid Dipropylene Glycol Sodium Palmitoyl Proline Disodium EDTA BHT Potassium Sorbate Phenoxyethanol Mica CI 77891 CI 77491 CI 77492 CI 77499 Water, Dimethicone, Butylene Glycol, Caprylic/Capric Triglyceride, Glycerin, Bis-PEG-18 Methyl Ether Dimethyl Silane, Polysorbate 20, Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone, Polysilicone-11, Mangifera Indica Seed Butter, Phoenix Dactylifera Fruit Extract, Pisum Sativum Extract, Cucumis Sativus Fruit Extract, Crithmum Maritimum Extract, Laminaria Ochroleuca Extract, Commiphora Mukul Resin Extract, Triticum Vulgare Germ Extract, Bambusa Vulgaris Extract, Chlorella Vulgaris Extract, Laminaria Saccharina Extract, Brassica Campestris Sterols, Helianthus Annuus Seed Extract, Algae Extract, Hypnea Musciformis Extract, Sigesbeckia Orientalis Extract, Nymphaea Alba Flower Extract, Acetyl Glucosamine, Caffeine, Gelidiella Acerosa Extract, Coffea Arabica Seed Extract, Sodium Hyaluronate, Lactic Acid, Propylene Glycol Dicaprate, Saccharide Isomerate, Methyl Gluceth-20, Ethylhexylglycerin, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Helianthus Annuus Seedcake, Caprylyl Glycol, Isohexadecane, Tocopheryl Acetate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Glyceryl Polymethacrylate, Sodium Polyacrylate Starch, Squalane, Sodium PCA, Urea, Zea Mays Kernel Extract, Whey Protein, Palmaria Palmata Extract, Polysorbate 80 These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products. As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied. It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin. A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss. Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid. In practice, that translates to a long shelf life and a consistently elegant skin feel. While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns. Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source. This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out. This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%. Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane. What it does: Dimethicone comes in different viscosities: Depending on the viscosity, dimethicone has different properties. Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity. This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient. Note: Dimethicone may contribute to pilling. This i