Estée Lauder Perfectionist Pro Rapid Firm + Lift Treatment with Acetyl Hexapeptide-8 Versus The Ordinary Argireline Solution 10%

Estée Lauder Perfectionist Pro Rapid Firm + Lift Treatment with Acetyl Hexapeptide-8 Versus The Ordinary Argireline Solution 10% Detailed comparison of Estée Lauder Perfectionist Pro Rapid Firm + Lift Treatment with Acetyl Hexapeptide-8 versus The Ordinary Argireline Solution 10%. This anti-aging serum is formulated around Acetyl Glucosamine and Acetyl Hexapeptide-8 to soften the look of wrinkles. This anti-aging serum is formulated around Acetyl Hexapeptide-8 to soften the look of wrinkles. No concerns Water Dimethicone Butylene Glycol Caprylic/Capric Triglyceride Glycerin Bis-PEG-18 Methyl Ether Dimethyl Silane Polysorbate 20 Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone Polysilicone-11 Mangifera Indica Seed Butter Phoenix Dactylifera Fruit Extract Pisum Sativum Extract Cucumis Sativus Fruit Extract Crithmum Maritimum Extract Laminaria Ochroleuca Extract Commiphora Mukul Resin Extract Triticum Vulgare Germ Extract Bambusa Vulgaris Extract Chlorella Vulgaris Extract Laminaria Saccharina Extract Brassica Campestris Sterols Helianthus Annuus Seed Extract Algae Extract Hypnea Musciformis Extract Sigesbeckia Orientalis Extract Nymphaea Alba Flower Extract Acetyl Glucosamine Caffeine Gelidiella Acerosa Extract Coffea Arabica Seed Extract Sodium Hyaluronate Lactic Acid Propylene Glycol Dicaprate Saccharide Isomerate Methyl Gluceth-20 Ethylhexylglycerin Acrylamide/Sodium Acryloyldimethyltaurate Copolymer Helianthus Annuus Seedcake Caprylyl Glycol Isohexadecane Tocopheryl Acetate Acrylates/C10-30 Alkyl Acrylate Crosspolymer Glyceryl Polymethacrylate Sodium Polyacrylate Starch Squalane Sodium PCA Urea Zea Mays Kernel Extract Whey Protein Palmaria Palmata Extract Polysorbate 80 Acetyl Hexapeptide-8 Triolein Hydrolyzed Rice Extract Linoleic Acid Trehalose Glycine Soja Protein Glucosamine Hcl Phospholipids Laminaria Digitata Extract Hordeum Vulgare Extract Polyquaternium-51 Palmitoyl Hexapeptide-12 Ergothioneine Aminopropyl Ascorbyl Phosphate PEG-8 Phytosteryl Canola Glycerides Pentylene Glycol Oleic Acid Palmitic Acid Xanthan Gum Parfum Sodium Hydroxide Citric Acid Silica Calcium Chloride Stearic Acid Dipropylene Glycol Sodium Palmitoyl Proline Disodium EDTA BHT Potassium Sorbate Phenoxyethanol Mica CI 77891 CI 77491 CI 77492 CI 77499 Water, Dimethicone, Butylene Glycol, Caprylic/Capric Triglyceride, Glycerin, Bis-PEG-18 Methyl Ether Dimethyl Silane, Polysorbate 20, Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone, Polysilicone-11, Mangifera Indica Seed Butter, Phoenix Dactylifera Fruit Extract, Pisum Sativum Extract, Cucumis Sativus Fruit Extract, Crithmum Maritimum Extract, Laminaria Ochroleuca Extract, Commiphora Mukul Resin Extract, Triticum Vulgare Germ Extract, Bambusa Vulgaris Extract, Chlorella Vulgaris Extract, Laminaria Saccharina Extract, Brassica Campestris Sterols, Helianthus Annuus Seed Extract, Algae Extract, Hypnea Musciformis Extract, Sigesbeckia Orientalis Extract, Nymphaea Alba Flower Extract, Acetyl Glucosamine, Caffeine, Gelidiella Acerosa Extract, Coffea Arabica Seed Extract, Sodium Hyaluronate, Lactic Acid, Propylene Glycol Dicaprate, Saccharide Isomerate, Methyl Gluceth-20, Ethylhexylglycerin, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Helianthus Annuus Seedcake, Caprylyl Glycol, Isohexadecane, Tocopheryl Acetate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Glyceryl Polymethacrylate, Sodium Polyacrylate Starch, Squalane, Sodium PCA, Urea, Zea Mays Kernel Extract, Whey Protein, Palmaria Palmata Extract, Polysorbate 80 Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive. Another perk of this ingredient is that it stays functional across a wide pH range (3-10). You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own. Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU. Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages. Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon. Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products. This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus. Both potassium sorbate and sorbic acid can be found in baked goods,