Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Estée Lauder Revitalizing Supreme + Night Versus Drunk Elephant Protini Polypeptide Cream

Estée Lauder Revitalizing Supreme + Night Versus Drunk Elephant Protini Polypeptide Cream Detailed comparison of Estée Lauder Revitalizing Supreme + Night versus Drunk Elephant Protini Polypeptide Cream. This anti-aging night moisturizer is formulated around N

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Estée Lauder Revitalizing Supreme + Night Versus Drunk Elephant Protini Polypeptide Cream Detailed comparison of Estée Lauder Revitalizing Supreme + Night versus Drunk Elephant Protini Polypeptide Cream. This anti-aging night moisturizer is formulated around Niacinamide and Moringa Oleifera Seed Extract to soften the look of wrinkles and hydrate skin. This anti-aging moisturizer is formulated around Sclerocarya Birrea Seed Oil and Sh-Oligopeptide-1 to soften the look of wrinkles and hydrate skin. Water Glycine Soja Oil Caprylic/Capric/Myristic/Stearic Triglyceride Glycerin Prunus Amygdalus Dulcis Oil Dimethicone Stearyl Alcohol Butylene Glycol Steareth-2 Cocos Nucifera Oil Vitis Vinifera Seed Oil Glyceryl Stearate Niacinamide Propanediol Steareth-21 Moringa Oleifera Seed Extract Limonium Vulgare Flower/Leaf/Stem Extract Sodium Hyaluronate Acetyl Hexapeptide-8 Laminaria Digitata Extract Whey Protein Acetyl Glucosamine Opuntia Tuna Fruit Extract Tocopheryl Acetate Citrullus Lanatus Fruit Extract Persea Gratissima Oil Mangifera Indica Seed Oil Aminopropyl Ascorbyl Phosphate Algae Extract Caffeine Cucumis Sativus Fruit Extract Pyrus Malus Fruit Extract Narcissus Tazetta Bulb Extract Sigesbeckia Orientalis Extract Butyrospermum Parkii Butter Lens Esculenta Fruit Extract Silybum Marianum Seed Oil Limnanthes Alba Seed Oil Hordeum Vulgare Extract Simmondsia Chinensis Seed Oil Macadamia Integrifolia Seed Oil Olea Europaea Fruit Oil Dextrin Palmitate Sodium Hydroxide Carbomer Behenyl Alcohol Caprylyl Glycol Hydroxyethyl Urea Propylene Glycol Dicaprate Cholesterol Isoceteth-20 Lactoperoxidase Helianthus Annuus Seedcake Sodium Polyaspartate Sorbitol Glucose Cetyl Alcohol Myristyl Alcohol Sodium Lactate Citric Acid Sodium PCA Glucose Oxidase Potassium Phosphate Sodium Chloride Parfum Disodium EDTA BHT Potassium Sorbate Sodium Benzoate Phenoxyethanol CI 19140 CI 14700 CI 77491 CI 77492 Water, Glycine Soja Oil, Caprylic/Capric/Myristic/Stearic Triglyceride, Glycerin, Prunus Amygdalus Dulcis Oil, Dimethicone, Stearyl Alcohol, Butylene Glycol, Steareth-2, Cocos Nucifera Oil, Vitis Vinifera Seed Oil, Glyceryl Stearate, Niacinamide, Propanediol, Steareth-21, Moringa Oleifera Seed Extract, Limonium Vulgare Flower/Leaf/Stem Extract, Sodium Hyaluronate, Acetyl Hexapeptide-8, Laminaria Digitata Extract, Whey Protein, Acetyl Glucosamine, Opuntia Tuna Fruit Extract, Tocopheryl Acetate, Citrullus Lanatus Fruit Extract, Persea Gratissima Oil, Mangifera Indica Seed Oil, Aminopropyl Ascorbyl Phosphate, Algae Extract, Caffeine, Cucumis Sativus Fruit Extract, Pyrus Malus Fruit Extract, Narcissus Tazetta Bulb Extract, Sigesbeckia Orientalis Extract, Butyrospermum Parkii Butter, Lens Esculenta Fruit Extract, Silybum Marianum Seed Oil, Limnanthes Alba Seed Oil, Hordeum Vulgare Extract, Simmondsia Chinensis Seed Oil, Macadamia Integrifolia Seed Oil, Olea Europaea Fruit Oil, Dextrin Palmitate, Sodium Hydroxide, Carbomer, Behenyl Alcohol, Caprylyl Glycol, Hydroxyethyl Urea, Propylene Glycol Dicaprate, Cholesterol, Isoceteth-20, Lactoperoxidase, Helianthus Annuus Seedcake, Sodium Polyaspartate, Sorbitol, Glucose, Cetyl Alcohol, Myristyl Alcohol, Sodium Lactate, Citric Acid, Sodium PCA, Glucose Oxidase, Potassium Phosphate, Sodium Chloride, Parfum, Disodium EDTA, BHT, Potassium Sorbate, Sodium Benzoate, Phenoxyethanol, CI 19140, CI 14700, CI 77491, CI 77492 Dicaprylyl Carbonate Cetearyl Alcohol Cetearyl Olivate Sorbitan Olivate Sclerocarya Birrea Seed Oil Bacillus/Folic Acid F These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive. Another perk of this ingredient i