Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Genabelle PDRN Rejuvenating Cream Versus D'Alba Peptide No Sebum Repair Cream

Genabelle PDRN Rejuvenating Cream Versus D'Alba Peptide No Sebum Repair Cream Detailed comparison of Genabelle PDRN Rejuvenating Cream versus D'Alba Peptide No Sebum Repair Cream. This barrier-repair moisturizer is formulated around Niacinamide and Centella As

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Genabelle PDRN Rejuvenating Cream Versus D'Alba Peptide No Sebum Repair Cream Detailed comparison of Genabelle PDRN Rejuvenating Cream versus D'Alba Peptide No Sebum Repair Cream. This barrier-repair moisturizer is formulated around Niacinamide and Centella Asiatica Extract to strengthen the skin barrier and soften the look of wrinkles. This oil-control moisturizer is formulated around Niacinamide and Acetyl Hexapeptide-8 to balance excess oil and strengthen the skin barrier. Water Dipropylene Glycol Glycerin Phenyl Trimethicone Oenothera Biennis Oil Cetearyl Alcohol Glyceryl Glucoside Niacinamide Beeswax Chamomilla Recutita Flower Extract Centella Asiatica Extract Portulaca Oleracea Extract Vitex Agnus Castus Extract 1,2-Hexanediol Glyceryl Stearate Dimethicone Dimethicone/Vinyl Dimethicone Crosspolymer Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone Butylene Glycol Ceramide NP Sodium DNA Sodium Polyacrylate Sodium Hyaluronate Adenosine Acetyl Hexapeptide-8 Sh-Oligopeptide-1 Arginine Carbomer Tocopherol Tranexamic Acid Trideceth-6 PEG-100 Stearate Hydrogenated Lecithin Hydrogenated Polydecene Hydroxyacetophenone Disodium EDTA Parfum Water, Dipropylene Glycol, Glycerin, Phenyl Trimethicone, Oenothera Biennis Oil, Cetearyl Alcohol, Glyceryl Glucoside, Niacinamide, Beeswax, Chamomilla Recutita Flower Extract, Centella Asiatica Extract, Portulaca Oleracea Extract, Vitex Agnus Castus Extract, 1,2-Hexanediol, Glyceryl Stearate, Dimethicone, Dimethicone/Vinyl Dimethicone Crosspolymer, Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone, Butylene Glycol, Ceramide NP, Sodium DNA, Sodium Polyacrylate, Sodium Hyaluronate, Adenosine, Acetyl Hexapeptide-8, Sh-Oligopeptide-1, Arginine, Carbomer, Tocopherol, Tranexamic Acid, Trideceth-6, PEG-100 Stearate, Hydrogenated Lecithin, Hydrogenated Polydecene, Hydroxyacetophenone, Disodium EDTA, Parfum Caprylic/Capric Triglyceride Squalane Cetearyl Olivate Sorbitan Olivate Cetearyl Glucoside Hydroxypropyl Methylcellulose Artemisia Annua Extract Nelumbo Nucifera Flower Extract Oryza Sativa Extract Saccharomyces Ferment Octyldodecanol Panthenol Melaleuca Alternifolia Leaf Extract Helianthus Annuus Seed Oil Lavandula Angustifolia Oil Pullulan Tuber Magnatum Extract Calamine Dipotassium Glycyrrhizate Tocopheryl Acetate Ethylhexylglycerin Pentylene Glycol Polygonum Cuspidatum Root Extract Scutellaria Baicalensis Root Extract Biosaccharide Gum-1 Alkanna Tinctoria Root Extract Caprylyl Glycol Betaine Salicylate Camellia Sinensis Leaf Extract Glycyrrhiza Glabra Root Extract Porphyridium Cruentum Extract Rosmarinus Officinalis Leaf Extract Glucose Sodium Hyaluronate Crosspolymer Hydrolyzed Hyaluronic Acid Hyaluronic Acid Hydrolyzed Sodium Hyaluronate Water, Butylene Glycol, Glycerin, Caprylic/Capric Triglyceride, Squalane, 1,2-Hexanediol, Niacinamide, Cetearyl Olivate, Sorbitan Olivate, Dimethicone, Cetearyl Alcohol, Cetearyl Glucoside, Carbomer, Hydroxypropyl Methylcellulose, Artemisia Annua Extract, Nelumbo Nucifera Flower Extract, Oryza Sativa Extract, Saccharomyces Ferment, Arginine, Octyldodecanol, Panthenol, Melaleuca Alternifolia Leaf Extract, Helianthus Annuus Seed Oil, Lavandula Angustifolia Oil, Pullulan, Tuber Magnatum Extract, Calamine, Centella Asiatica Extract, Dipotassium Glycyrrhizate, Tocopheryl Acetate, Ethylhexylglycerin, Adenosine, Sodium Hyaluronate, Hydrogenated Lecithin, Pentylene Glycol, Ceramide NP, Polygonum Cuspidatum Root Extract, Scutellaria Baicalensis Root Extract, Bios Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. 1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. It is a: Humectant, drawing moisture into the skin Emollient, helping to soften skin Solvent, dispersing and stabilizing formulas Preservative booster, enhancing the antimicrobial activity of other preservatives Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent. The way it works is fairly well mapped out: Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going. The clinical backing is pretty solid too. A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months. A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration. On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses. This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization. Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it