Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

GHK-Cu AHK-Cu for Skin + Hair Research: Comparison

Before selecting a peptide for a specific research application, understand the functional differences between GHK-Cu and AHK-Cu and how those differences map to study design. GHK-Cu Lysyl oxidase activation, MMP suppression, TGF-β modulation Dermal fibroblasts

This source-based comparison does not add ratings or recommend a winner.

  • Before selecting a peptide for a specific research application, understand the functional differences between GHK-Cu and AHK-Cu and how those differences map to study design.
  • GHK-Cu
  • Lysyl oxidase activation, MMP suppression, TGF-β modulation
  • Dermal fibroblasts, keratinocytes, wound models
  • 7–14 days at 2–8°C
  • 1–10 μM in vitro, 2–5 mM topical
  • High concentrations (>50 μM) can trigger apoptosis in certain cell lines
  • AHK-Cu
  • VEGF receptor upregulation, Wnt/β-catenin pathway modulation
  • Dermal papilla cells, hair follicles
  • 5–7 days at 2–8°C
  • 5–20 μM in follicle cultures
  • Faster degradation in aqueous solution; less characterized mechanistically than GHK-Cu