Ingredient or product comparison
GHK-Cu COA Data Points: Quick Reference Comparison
Purity (%) ≥98% HPLC with UV detection at 220 nm 1 Da deviation or missing entirely Peptide identity, structural integri
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- Purity (%)
- ≥98%
- HPLC with UV detection at 220 nm
- <95% or missing chromatogram
- Synthesis byproducts, truncated sequences, degradation
- Molecular Weight (Da)
- 340.87 ± 0.5
- ESI-MS or MALDI-TOF
- >1 Da deviation or missing entirely
- Peptide identity, structural integrity, incorrect compound
- Bacterial Endotoxin (EU/mg)
- <10 EU/mg
- LAL (Limulus Amebocyte Lysate) assay
- >50 EU/mg
- Gram-negative bacterial contamination from water or synthesis equipment
- Residual Solvents (ppm)
- <5000 ppm total
- GC-MS (gas chromatography-mass spec)
- >10,000 ppm or solvent not listed
- Acetonitrile, TFA, methanol left from purification. Skin irritants
- Heavy Metals (ppm)
- <10 ppm lead, <20 ppm total
- ICP-MS (inductively coupled plasma)
- >30 ppm or testing omitted
- Lead, cadmium, arsenic. Neurotoxic and carcinogenic contaminants
- Bottom Line
- All five sections must pass. One failure disqualifies the batch
- Third-party lab with ISO 17025 accreditation
- COA reused from old batch, missing batch number match, or in-house testing only
- Product safety, dose accuracy, and peptide identity require independent verification