Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

GHK-Cu Cosmetic for Fine Lines: Product Type Comparison

Serum (water-based) 1–2% Hyaluronic acid + MSM 6–9 months (airless) Daily application under moisturizer, rapid absorption Highest concentration delivery; requires separate moisturizer for occlusivity Cream (emulsion) 0.5–1.5% Phospholipid vesicles 12 months (a

This source-based comparison does not add ratings or recommend a winner.

  • Serum (water-based)
  • 1–2%
  • Hyaluronic acid + MSM
  • 6–9 months (airless)
  • Daily application under moisturizer, rapid absorption
  • Highest concentration delivery; requires separate moisturizer for occlusivity
  • Cream (emulsion)
  • 0.5–1.5%
  • Phospholipid vesicles
  • 12 months (airless)
  • All-in-one AM/PM treatment
  • Easier compliance; lower concentration offset by lipid matrix penetration
  • Eye Cream
  • 0.5–1%
  • Peptide fragments ≤500 Da
  • 9 months (tube)
  • Periorbital fine lines, crepey lids
  • Thin skin-optimized; avoid if sensitive to trace copper
  • Mask (rinse-off)
  • 0.5%
  • Contact time ≥20 min
  • 6 months (single-use sachets)
  • Weekly intensive treatment
  • Brief exposure limits penetration; best as adjunct, not primary