Ingredient or product comparison
GHK-Cu for Dark Circles Under Eyes Research: Product Comparison
Pre-mixed aqueous serum 0.5–1% (degraded to ~0.2% after 30 days) Poor. Oxidizes within 4–6 weeks of opening Convenient but compromised potency Acceptable for initial trials; replace monthly Anhydrous silicone suspension 1–2% (stable for 90+ days) Excellent. Co
This source-based comparison does not add ratings or recommend a winner.
- Pre-mixed aqueous serum
- 0.5–1% (degraded to ~0.2% after 30 days)
- Poor. Oxidizes within 4–6 weeks of opening
- Convenient but compromised potency
- Acceptable for initial trials; replace monthly
- Anhydrous silicone suspension
- 1–2% (stable for 90+ days)
- Excellent. Copper protected from oxidation
- Apply to dry skin; may require emulsifier
- Best balance of stability and usability
- Lyophilized powder (reconstitute fresh)
- 2–5% (100% potency at mixing)
- Optimal. No degradation until reconstituted
- Requires sterile technique; 14-day use window
- Gold standard for research-grade application
- Oil-based formulation
- 0.5–1% (stable 60–90 days)
- Good. Lipid environment slows oxidation
- Works under occlusive moisturizers
- Reliable for sustained protocols