Ingredient or product comparison
GHK-Cu Hair Growth: Protocol Comparison
Topical serum alone 200–400 mcg/mL Twice daily Minimal regrowth (5–8% density increase at 24 weeks) 50–100 micrometers (epidermis only) Insufficient for most cases. Peptide doesn't reach follicle depth without mechanical delivery Microneedling + serum Serum tw
This source-based comparison does not add ratings or recommend a winner.
- Topical serum alone
- 200–400 mcg/mL
- Twice daily
- Minimal regrowth (5–8% density increase at 24 weeks)
- 50–100 micrometers (epidermis only)
- Insufficient for most cases. Peptide doesn't reach follicle depth without mechanical delivery
- Microneedling + serum
- Serum twice daily, needling weekly
- Significant regrowth (18–31% density increase at 20 weeks)
- 1.0–1.5mm (dermal layer, follicle bulb zone)
- Gold standard for at-home application. Evidence-backed and cost-effective
- Liposomal formulation
- 300–500 mcg/mL
- Moderate regrowth (12–15% density increase at 16 weeks)
- 200–400 micrometers (upper dermis)
- Improved penetration vs standard topical, but expensive and still inferior to microneedling
- Iontophoresis device
- 300 mcg/mL
- Once daily (device-dependent)
- Inconsistent results (8–22% variation across trials)
- Variable (device-dependent)
- Theoretical benefit not reliably demonstrated. Clinical data too inconsistent to recommend