Ingredient or product comparison
GHK-Cu Lyophilized Powder: Handling Comparison
Lyophilized (unopened) −20°C 24–36 months Minimal (opaque packaging) Negligible if sealed Gold standard for long-term stability. No degradation pathway active at subzero temps Lyophilized (opened vial) 6–12 months Moderate (hygroscopic) Moderate (atmospheric m
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- Lyophilized (unopened)
- −20°C
- 24–36 months
- Minimal (opaque packaging)
- Negligible if sealed
- Gold standard for long-term stability. No degradation pathway active at subzero temps
- Lyophilized (opened vial)
- 6–12 months
- Moderate (hygroscopic)
- Moderate (atmospheric moisture)
- Reseal immediately; each opening introduces humidity that accelerates degradation
- Reconstituted (bacteriostatic water)
- 2–8°C
- 28 days maximum
- High (requires amber vial)
- High without sterile technique
- Time-limited stability. Copper oxidation and peptide hydrolysis are active at refrigeration temps
- Reconstituted (sterile water only)
- 48–72 hours
- High
- Very high (no antimicrobial)
- Not recommended for multi-dose use; bacterial growth begins within 24 hours
- Room temperature (any state)
- 20–25°C
- <24 hours
- Very high
- Critical
- Avoid entirely. Accelerates all degradation pathways simultaneously