Ingredient or product comparison
GHK-Cu Myths Cost Money Health: Peptide Comparison
GHK-Cu TIMP upregulation, MMP inhibition, TGF-β modulation 2–3 µM in culture; 0.05–0.1% topical pH 6.8–7.4, argon storage, <8°C $120–180 (research grade) Gold standard for collagen remodeling. But only when formulation chemistry is correct Copper-AHK Non-speci
This source-based comparison does not add ratings or recommend a winner.
- GHK-Cu
- TIMP upregulation, MMP inhibition, TGF-β modulation
- 2–3 µM in culture; 0.05–0.1% topical
- pH 6.8–7.4, argon storage, <8°C
- $120–180 (research grade)
- Gold standard for collagen remodeling. But only when formulation chemistry is correct
- Copper-AHK
- Non-specific copper delivery, minimal TIMP effect
- 5–10 µM
- Less pH-sensitive than GHK-Cu
- $60–90
- Cheaper alternative with weaker evidence base
- GHK (copper-free)
- Mild TGF-β activation without MMP inhibition
- 10–20 µM
- Stable across wider pH range
- $40–70
- Minimal tissue remodeling effect without copper
- Matrixyl (palmitoyl peptides)
- TGF-β upregulation via different receptor pathway
- 3–5% topical
- Room temperature stable
- $80–120
- Different mechanism. Can be combined with GHK-Cu