Ingredient or product comparison
GHK-Cu Studied Wrinkles | Clinical vs Commercial Comparison
Before concluding that any peptide formulation 'works' based on marketing claims, it's essential to understand what the clinical data actually measured versus what over-the-counter products deliver. GHK-Cu Concentration 3 mM (1000 mcg/mL) 0.05–0.5 mM (often un
This source-based comparison does not add ratings or recommend a winner.
- Before concluding that any peptide formulation 'works' based on marketing claims, it's essential to understand what the clinical data actually measured versus what over-the-counter products deliver.
- GHK-Cu Concentration
- 3 mM (1000 mcg/mL)
- 0.05–0.5 mM (often undisclosed)
- Clinical dose 6–60× higher than retail
- Copper:Peptide Ratio
- 1:1 verified by mass spec
- Unverified, often excess copper
- Stoichiometry determines activity
- Vehicle pH
- 6.2–6.8 maintained
- Often >7.0 or <5.0
- Stability lost outside narrow range
- Wrinkle Measurement
- Profilometry (±0.01 mm precision)
- Self-reported or photography
- Objective vs subjective outcomes
- Trial Duration
- 12 weeks minimum
- Claims based on 2–4 weeks
- Collagen remodeling requires >8 weeks
- Statistical Significance
- p<0.001 with n>60
- No controlled data
- Marketing vs evidence