Glytone Mandelic Gentle Resurfacing Serum Versus SkinMedica TNS® Advanced+ Serum

Glytone Mandelic Gentle Resurfacing Serum Versus SkinMedica TNS® Advanced+ Serum Detailed comparison of Glytone Mandelic Gentle Resurfacing Serum versus SkinMedica TNS® Advanced+ Serum. This smoothing serum is formulated around Mandelic Acid and Lactobacillus/Punica Granatum Fruit Ferment Extract to refine skin texture and brighten dull-looking skin. Water Glycerin Mandelic Acid Lactobacillus/Punica Granatum Fruit Ferment Extract Propanediol Potassium Hydroxide Pentylene Glycol Panthenol Sodium Phytate Hydroxyacetophenone Sclerotium Gum Phytic Acid Leuconostoc/Radish Root Ferment Filtrate Ethylhexylglycerin Xanthan Gum Lecithin Pullulan Agastache Mexicana Flower/Leaf/Stem Extract Silica Tocopherol Water, Glycerin, Mandelic Acid, Lactobacillus/Punica Granatum Fruit Ferment Extract, Propanediol, Potassium Hydroxide, Pentylene Glycol, Panthenol, Sodium Phytate, Hydroxyacetophenone, Sclerotium Gum, Phytic Acid, Leuconostoc/Radish Root Ferment Filtrate, Ethylhexylglycerin, Xanthan Gum, Lecithin, Pullulan, Agastache Mexicana Flower/Leaf/Stem Extract, Silica, Tocopherol Human Neonatal Fibroblast Conditioned Media Glycereth-7 Triacetate Shea Butter Ethyl Esters Ethoxydiglycol Lactococcus Ferment Lysate Whey Protein Chlorella Vulgaris Extract Saccharide Isomerate Dimer Tripeptide-43 Vitis Vinifera Flower Cell Extract Pyrus Malus Fruit Extract Tocopheryl Acetate Polyacrylate Crosspolymer-6 Polyacrylate-13 Polyisobutene PEG-12 Dimethicone Butylene Glycol Sodium Citrate Polysorbate 20 Aminomethyl Propanol Disodium EDTA Phenoxyethanol Water, Pentylene Glycol, Human Neonatal Fibroblast Conditioned Media, Glycereth-7 Triacetate, Shea Butter Ethyl Esters, Glycerin, Ethoxydiglycol, Lactococcus Ferment Lysate, Whey Protein, Chlorella Vulgaris Extract, Saccharide Isomerate, Dimer Tripeptide-43, Vitis Vinifera Flower Cell Extract, Pyrus Malus Fruit Extract, Hydroxyacetophenone, Tocopheryl Acetate, Propanediol, Xanthan Gum, Polyacrylate Crosspolymer-6, Polyacrylate-13, Polyisobutene, Sclerotium Gum, PEG-12 Dimethicone, Lecithin, Pullulan, Butylene Glycol, Sodium Citrate, Polysorbate 20, Aminomethyl Propanol, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that: The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure. Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Hydroxyacetophenone is a small phenolic molecule that earns its place in a formulas as an antioxidant and preservative booster. As a phenol, it is able to neutralize free radicals to protect both the product and the skin from oxidative stress. Though it can't kill microbes on its own, it works as a good supporting agent when combined with other preservatives like Phenoxyethanol or 1,2-Hexanediol. This ingredient naturally occurs as piceol in Norwegian spruce needles (~0.4-1.1% dry weight and in cloudberries). Though the cosmetic-grade material is synthesized for purity and consistency. You'll usually see it used at low levels and suppliers recommend up to 1% added to a water phase. Safety testing was done at concentrations like 0.05% in SPF products and 0.5% in a Human Repeated Insult Patch Test. The safety evidence is assuring; this ingredient is safe for cosmetics in current use and also holds safety status as a food flavoring as well. An honest caveat: the "soothing" and "anti-inflammatory" claims come mostly from supplier marketing rather than published clinical trials. The Cosmetic Ingredient Review's own literature search found no useful efficacy studies on this ingredient. So the antioxidant and preservative-boosting roles are the well supported ones while the calming benefit is plausible but thinly evidenced. Overall, this is a well-tolerated, low-irritation multitasker that quietly helps a formula stay fresh and stable. Lecithin is a term for a group of