Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Haruharu Wonder Centella Phyto & 5 Peptide Concentrate Cream Versus MediCube Triple Collagen Cream

Haruharu Wonder Centella Phyto & 5 Peptide Concentrate Cream Versus MediCube Triple Collagen Cream Detailed comparison of Haruharu Wonder Centella Phyto & 5 Peptide Concentrate Cream versus MediCube Triple Collagen Cream. This anti-aging moisturizer is formula

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Haruharu Wonder Centella Phyto & 5 Peptide Concentrate Cream Versus MediCube Triple Collagen Cream Detailed comparison of Haruharu Wonder Centella Phyto & 5 Peptide Concentrate Cream versus MediCube Triple Collagen Cream. This anti-aging moisturizer is formulated around Centella Asiatica Extract and Madecassoside to soften the look of wrinkles and calm redness. This anti-aging moisturizer is formulated around Niacinamide and Collagen Extract to soften the look of wrinkles and hydrate skin. Water Glycerin Butylene Glycol Caprylic/Capric Triglyceride Helianthus Annuus Seed Oil Polyglyceryl-3 Distearate 1,2-Hexanediol Cetyl Alcohol Cetyl Palmitate Ammonium Acryloyldimethyltaurate/Vp Copolymer Sorbitan Palmitate Sorbitan Olivate Glyceryl Stearate Stearyl Alcohol Xanthan Gum Glyceryl Stearate Citrate Myristyl Alcohol Squalane Caffeine Hydrolyzed Soy Protein Hydrogenated Lecithin Pentylene Glycol Ethylhexylglycerin Adenosine Butyrospermum Parkii Butter Phytosterols Lauryl Alcohol Centella Asiatica Extract Hydrolyzed Pea Protein Madecassoside Asiaticoside Caprylyl Glycol Xylitylglucoside Anhydroxylitol Copper Tripeptide-1 Xylitol Acetyl Hexapeptide-8 Asiatic Acid Madecassic Acid Glucose Ceramide NP Hippophae Rhamnoides Fruit Extract Oligopeptide-32 Oligopeptide-29 Palmitoyl Pentapeptide-4 Water, Glycerin, Butylene Glycol, Caprylic/Capric Triglyceride, Helianthus Annuus Seed Oil, Polyglyceryl-3 Distearate, 1,2-Hexanediol, Cetyl Alcohol, Cetyl Palmitate, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Sorbitan Palmitate, Sorbitan Olivate, Glyceryl Stearate, Stearyl Alcohol, Xanthan Gum, Glyceryl Stearate Citrate, Myristyl Alcohol, Squalane, Caffeine, Hydrolyzed Soy Protein, Hydrogenated Lecithin, Pentylene Glycol, Ethylhexylglycerin, Adenosine, Butyrospermum Parkii Butter, Phytosterols, Lauryl Alcohol, Centella Asiatica Extract, Hydrolyzed Pea Protein, Madecassoside, Asiaticoside, Caprylyl Glycol, Xylitylglucoside, Anhydroxylitol, Copper Tripeptide-1, Xylitol, Acetyl Hexapeptide-8, Asiatic Acid, Madecassic Acid, Glucose, Ceramide NP, Hippophae Rhamnoides Fruit Extract, Oligopeptide-32, Oligopeptide-29, Palmitoyl Pentapeptide-4 Dipropylene Glycol Cetearyl Alcohol Cyclopentasiloxane Triethylhexanoin Hydrogenated Polydecene Niacinamide Hydrogenated Poly(C6-14 Olefin) Cyclohexasiloxane Glyceryl Stearate Se Dioscorea Japonica Root Extract Aesculus Hippocastanum Extract Laminaria Japonica Extract Eclipta Prostrata Leaf Extract Collagen Extract Argania Spinosa Kernel Oil Sodium Hyaluronate Cetearyl Olivate C12-16 Alcohols Dimethicone PEG-100 Stearate Microcrystalline Cellulose Cetearyl Glucoside Fructose Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Palmitic Acid Betaine Cellulose Gum Hydrolyzed Corn Starch Polysorbate 60 Hydrogenated Polyisobutene Beta-Glucan Alcohol Disodium EDTA Isononyl Isononanoate Polyglyceryl-10 Stearate Sorbitan Isostearate Sucrose Stearic Acid Polyglyceryl-2 Dipolyhydroxystearate Fructooligosaccharides Inulin Lauryl Carbamate Hydrolyzed Hyaluronic Acid Citric Acid Disodium Stearoyl Glutamate Collagen Hydrolyzed Elastin Hyaluronic Acid Tocopherol Leuconostoc/Radish Root Ferment Filtrate Parfum Potassium Sorbate Linalool Benzyl Salicylate Limonene Hydroxycitronellal Water, Glycerin, Dipropylene Glycol, Cetearyl Alcohol, Cyclopentasiloxane, Caprylic/Capric Triglyceride, Triethylhexanoin, Hydrogenated Polydecene, 1,2-Hexanediol, Niacinamide, Hydrogenated Poly(C6-14 Olefin), Cyclohexasiloxane, Glyceryl Stearat These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. 1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. It is a: Humectant, drawing moisture into the skin Emollient, helping to soften skin Solvent, dispersing and stabilizing formulas Preservative booster, enhancing the antimicrobial activity of other preservatives Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent. The way it works is fairly well mapped out: Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going. The clinical backing is pretty solid too. A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months. A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration. On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses. This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization. Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. This ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients. Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL). In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!). Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo. Shea butter also conta