Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Hydropeptide Solar Defense Non-Tinted SPF 50 Versus MDSolarSciences Mineral Crème SPF 50

Hydropeptide Solar Defense Non-Tinted SPF 50 Versus MDSolarSciences Mineral Crème SPF 50 Detailed comparison of Hydropeptide Solar Defense Non-Tinted SPF 50 versus MDSolarSciences Mineral Crème SPF 50. This mineral sunscreen covers the full UV range and blocks

This source-based comparison does not add ratings or recommend a winner.

Hydropeptide Solar Defense Non-Tinted SPF 50 Versus MDSolarSciences Mineral Crème SPF 50 Detailed comparison of Hydropeptide Solar Defense Non-Tinted SPF 50 versus MDSolarSciences Mineral Crème SPF 50. This mineral sunscreen covers the full UV range and blocks ~98% of UVB at SPF 50. This hybrid sunscreen covers the full UV range and blocks ~98% of UVB at SPF 50. Titanium Dioxide 3% Zinc Oxide 7% 1,2-Hexanediol Allantoin Alumina Biotin Butylene Glycol C12-15 Alkyl Benzoate Calendula Officinalis Flower Extract Camellia Oleifera Leaf Extract Caprylyl Glycol Caprylyl Methicone Cetyl Alcohol Chamomilla Recutita Flower Extract Citric Acid Cucumis Sativus Fruit Extract Cyclomethicone Cyclopentasiloxane Dimethicone Disodium EDTA Ethylhexyl Palmitate Euterpe Oleracea Fruit Extract Glycerin Glyceryl Caprylate Glyceryl Stearate Glyceryl Undecylenate Hydrolyzed Yeast Protein Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Kaempferia Galanga Root Extract Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone Niacinamide Panthenol PEG-100 Stearate Pentylene Glycol Polyhydroxystearic Acid Polysorbate 60 Propanediol Propylene Glycol Pyridoxine Hcl Saccharomyces Cerevisiae Extract Sodium Citrate Sodium Hyaluronate Sodium PCA Thermus Thermophillus Ferment Triethoxycaprylylsilane Triethoxysilylethyl Polydimethylsiloxyethyl Hexyl Dimethicone Water Xanthan Gum Titanium Dioxide 3%, Zinc Oxide 7%, 1,2-Hexanediol, Allantoin, Alumina, Biotin, Butylene Glycol, C12-15 Alkyl Benzoate, Calendula Officinalis Flower Extract, Camellia Oleifera Leaf Extract, Caprylyl Glycol, Caprylyl Methicone, Cetyl Alcohol, Chamomilla Recutita Flower Extract, Citric Acid, Cucumis Sativus Fruit Extract, Cyclomethicone, Cyclopentasiloxane, Dimethicone, Disodium EDTA, Ethylhexyl Palmitate, Euterpe Oleracea Fruit Extract, Glycerin, Glyceryl Caprylate, Glyceryl Stearate, Glyceryl Undecylenate, Hydrolyzed Yeast Protein, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Kaempferia Galanga Root Extract, Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone, Niacinamide, Panthenol, PEG-100 Stearate, Pentylene Glycol, Polyhydroxystearic Acid, Polysorbate 60, Propanediol, Propylene Glycol, Pyridoxine Hcl, Saccharomyces Cerevisiae Extract, Sodium Citrate, Sodium Hyaluronate, Sodium PCA, Thermus Thermophillus Ferment, Triethoxycaprylylsilane, Triethoxysilylethyl Polydimethylsiloxyethyl Hexyl Dimethicone, Water, Xanthan Gum Titanium Dioxide 2% Zinc Oxide 17% Caprylic/Capric Triglyceride Dimethicone Crosspolymer Dimethicone/Vinyl Dimethicone Crosspolymer Butyloctyl Salicylate Glyceryl Isostearate Polysilicone-15 Tetrahexyldecyl Ascorbate Camellia Sinensis Leaf Extract Punica Granatum Extract Vaccinium Macrocarpon Fruit Extract Silica CI 77891 CI 77492 CI 77491 CI 77499 Titanium Dioxide 2%, Zinc Oxide 17%, Dimethicone, Caprylic/Capric Triglyceride, Dimethicone Crosspolymer, Dimethicone/Vinyl Dimethicone Crosspolymer, Butyloctyl Salicylate, Glyceryl Isostearate, Polysilicone-15, Tetrahexyldecyl Ascorbate, Camellia Sinensis Leaf Extract, Punica Granatum Extract, Vaccinium Macrocarpon Fruit Extract, Silica, Polyhydroxystearic Acid, CI 77891, CI 77492, CI 77491, CI 77499 These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane. What it does: Dimethicone comes in different viscosities: Depending on the viscosity, dimethicone has different properties. Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity. This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient. Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy. Polyhydroxystearic Acid is a vegetable-derived soft wax made from castor oil. It's an emulsion stabilizer, thickener, and film former. You'll likely see it in sunscreens because it helps disperse pigments and UV-reflecting minerals like titanium dioxide and zinc oxide evenly. Depending on the concentration, it can drastically change the texture of a product from pasty solid (like lipstick) to sprayable liquid. The CIR Expert Panel for Cosmetic Ingredient Safety has concluded this ingredient to be safe in cosmetics. The highest reported use concentration is 14.2% in lipsticks. Titanium Dioxide (TD) is a mineral UV filter widely used in sunscreens and cosmetics. It's one of only two UV filters officially classified as "mineral" by regulatory agencies (the other being Zinc Oxide). A really common myth is that mineral filters work by reflecting UV light off your skin like tiny mirrors. They don't only do that; modern research shows TD protects mostly by absorbing UV radiation, the same way chemical filters do. When researchers measured this, reflection accounted for only about 4-5% of the protection (and less than SPF 2 on its own). The other ~95% comes from absorption: the UV photons hit the particle and their energy gets soaked up by its semiconductor band gap rather than bouncing off. So "reflects vs. absorbs" was never really the right way to split mineral from chemical filters. TD gives broad-spectrum protection that's strongest in the UVB and UVA-2 range and weaker in the UVA-1 range. Its UVA protection isn't quite as strong as Zinc Oxide's which is why you'll often see the two paired together. Together, they make a solid broad-spectrum system. TD is a great pick for sensitive, acne-prone, or redness-prone skin because it's non-irritating and chemically inert. Regulatory reviews classify it as a non-sensitizer and mild-to-non-irritant. It's also unlikely to cause the "eye sting" some chemical filters are known for. The main trade-off is cosmetic; TD can leave a white cast and has a thicker texture. This is why mineral sunscreens are oft