Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

IMAGE skincare Ormedic Sheer Pink Lip Enhancement Complex Versus Kopari Tri-Peptide Lip Cloud

IMAGE skincare Ormedic Sheer Pink Lip Enhancement Complex Versus Kopari Tri-Peptide Lip Cloud Detailed comparison of IMAGE skincare Ormedic Sheer Pink Lip Enhancement Complex versus Kopari Tri-Peptide Lip Cloud. This anti-aging lip moisturizer is formulated ar

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IMAGE skincare Ormedic Sheer Pink Lip Enhancement Complex Versus Kopari Tri-Peptide Lip Cloud Detailed comparison of IMAGE skincare Ormedic Sheer Pink Lip Enhancement Complex versus Kopari Tri-Peptide Lip Cloud. This anti-aging lip moisturizer is formulated around Persea Gratissima Oil and Atelocollagen to soften the look of wrinkles and hydrate lips. This anti-aging lip moisturizer is formulated around Ricinus Communis Seed Oil and Cocos Nucifera Oil to soften the look of wrinkles and hydrate lips. Hydrogenated Polyisobutene Ethylene/Propylene/Styrene Copolymer Persea Gratissima Oil Phenyl Trimethicone Pentaerythrityl Tetraisostearate Ethylhexyl Palmitate PPG-12/Smdi Copolymer Tribehenin Butylene/Ethylene/Styrene Copolymer Diisopropyl Dimer Dilinoleate Aroma Tocopheryl Acetate Mica Limonene CI 77891 Silica Dimethyl Silylate Sorbitan Isostearate Butylene Glycol Pentylene Glycol Sodium Chondroitin Sulfate Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate Atelocollagen Caesalpinia Sappan Bark Extract Tocopherol Linalool Citral Tin Oxide Palmitoyl Tripeptide-1 Oryzanol Ubiquinone Hydrogenated Polyisobutene, Ethylene/Propylene/Styrene Copolymer, Persea Gratissima Oil, Phenyl Trimethicone, Pentaerythrityl Tetraisostearate, Ethylhexyl Palmitate, PPG-12/Smdi Copolymer, Tribehenin, Butylene/Ethylene/Styrene Copolymer, Diisopropyl Dimer Dilinoleate, Aroma, Tocopheryl Acetate, Mica, Limonene, CI 77891, Silica Dimethyl Silylate, Sorbitan Isostearate, Butylene Glycol, Pentylene Glycol, Sodium Chondroitin Sulfate, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Atelocollagen, Caesalpinia Sappan Bark Extract, Tocopherol, Linalool, Citral, Tin Oxide, Palmitoyl Tripeptide-1, Oryzanol, Ubiquinone Ricinus Communis Seed Oil Cocos Nucifera Oil Capryloyl Glycerin/Sebacic Acid Copolymer Diheptyl Succinate Prunus Armeniaca Kernel Oil Brassica Campestris/Aleurites Fordi Oil Copolymer Oryza Sativa Bran Oil Oryza Sativa Bran Wax Glyceryl Behenate Water Mentha Piperita Oil Menthol Sodium Hyaluronate CI 77492 CI 15850 Ricinus Communis Seed Oil, Cocos Nucifera Oil, Capryloyl Glycerin/Sebacic Acid Copolymer, Diheptyl Succinate, Tribehenin, Prunus Armeniaca Kernel Oil, Brassica Campestris/Aleurites Fordi Oil Copolymer, Oryza Sativa Bran Oil, Oryza Sativa Bran Wax, Glyceryl Behenate, Ethylhexyl Palmitate, Water, Mentha Piperita Oil, Tocopherol, Menthol, Sorbitan Isostearate, Sodium Hyaluronate, CI 77492, CI 15850, Palmitoyl Tripeptide-1 These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Ethylhexyl Palmitate, also known as octyl palmitate, is created from 2-ethylhexyl alcohol and palmitic acid. In cosmetics, it plays many roles: One thing worth noting: a controlled study found this ingredient applied under occlusion to acne-prone subjects increased microcomedones. Just keep in mind this was under occlusive conditions and don't reflect how most products are used day-to-day. For most people, this is a well-tolerated and lightweight ingredient. This ingredient may not be fungal acne safe because it is an ester of palmitic acid, a C16 fatty acid that falls within the C11-24 range that Malassezia can metabolize. Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid. That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference. Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid. In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing. Human clinical data is promising, but modest: A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm. A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks. You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7 as part of the Matrixyl 3000 complex. Fungal acne note: Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne. Sorbitan Isostearate is an emulsifer. It is created from isostearic acid and sorbitol. As an emulsifier, it keeps the water and oil ingredients from separating. This keeps formulas stable and smooth. In a 24 hour occlusive patch test on 56 subjects, 10% sorbitan isostearate was completely non-irritating. Most formulas use less than 10%. Because it's a fatty acid ester, it may not be fungal acne safe since the Malassezia yeast can utilize it as a nutrient source. Tocopherol is a fat-soluble antioxidant known as Vitamin E. You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your