Is Clinical Retinol+ Emulsion 0.3 Versus Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment

Is Clinical Retinol+ Emulsion 0.3 Versus Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment Detailed comparison of Is Clinical Retinol+ Emulsion 0.3 versus Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment. This anti-aging emulsion is formulated around Ectoin and Bakuchiol to soften the look of wrinkles and refine skin texture. This anti-aging treatment is formulated around Bakuchiol and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture. Water Glycerin Squalane Pentylene Glycol Sodium Hyaluronate Ectoin Glyceryl Citrate/Lactate/Linoleate/Oleate Polyglyceryl-4 Cocoate Polyglyceryl-3 Cocoate Glyceryl Caprylate Chlorella Vulgaris Extract Tocopherol Butylene Glycol Bakuchiol Triethanolamine Carbomer Retinol Phragmites Communis Extract Poria Cocos Extract Oryza Sativa Bran Extract Rosmarinus Officinalis Leaf Extract Phosphatidylcholine Propanediol Butyrospermum Parkii Butter Polysorbate 20 Caprylic/Capric Triglyceride Lecithin Lactic Acid Polysorbate 40 Helianthus Annuus Extract Phenoxyethanol Polyacrylamide C13-14 Isoparaffin Laureth-7 Tripeptide-1 Dextran Ascorbic Acid Colloidal Gold Glutathione Panthenol Heptyl Undecylenate C13-16 Isoalkane Dipotassium Glycyrrhizate Bidens Pilosa Extract Elaeis Guineensis Oil Gossypium Herbaceum Seed Oil Linum Usitatissimum Seed Oil Glycine Soja Extract Sodium Hydroxide Disodium EDTA Phenylpropanol Ethylhexylglycerin Caprylyl/Capryl Glucoside Diisopropyl Adipate Triethyl Citrate Xanthan Gum Sorbitol Parfum Water, Glycerin, Squalane, Pentylene Glycol, Sodium Hyaluronate, Ectoin, Glyceryl Citrate/Lactate/Linoleate/Oleate, Polyglyceryl-4 Cocoate, Polyglyceryl-3 Cocoate, Glyceryl Caprylate, Chlorella Vulgaris Extract, Tocopherol, Butylene Glycol, Bakuchiol, Triethanolamine, Carbomer, Retinol, Phragmites Communis Extract, Poria Cocos Extract, Oryza Sativa Bran Extract, Rosmarinus Officinalis Leaf Extract, Phosphatidylcholine, Propanediol, Butyrospermum Parkii Butter, Polysorbate 20, Caprylic/Capric Triglyceride, Lecithin, Lactic Acid, Polysorbate 40, Helianthus Annuus Extract, Phenoxyethanol, Polyacrylamide, C13-14 Isoparaffin, Laureth-7, Tripeptide-1, Dextran, Ascorbic Acid, Colloidal Gold, Glutathione, Panthenol, Heptyl Undecylenate, C13-16 Isoalkane, Dipotassium Glycyrrhizate, Bidens Pilosa Extract, Elaeis Guineensis Oil, Gossypium Herbaceum Seed Oil, Linum Usitatissimum Seed Oil, Glycine Soja Extract, Sodium Hydroxide, Disodium EDTA, Phenylpropanol, Ethylhexylglycerin, Caprylyl/Capryl Glucoside, Diisopropyl Adipate, Triethyl Citrate, Xanthan Gum, Sorbitol, Parfum Dimethicone Pentaerythrityl Tetraisostearate Isononyl Isononanoate Arachidyl Alcohol Glyceryl Polymethacrylate Dimethicone Crosspolymer Behenyl Alcohol PEG-75 Shea Butter Glycerides Glyceryl Stearate C12-15 Alkyl Benzoate Tetrahexyldecyl Ascorbate Ceramide Ng Palmitoyl Tetrapeptide-7 Palmitoyl Hexapeptide-12 Glycyrrhiza Glabra Root Extract Avena Sativa Kernel Extract Arctium Lappa Root Extract Salix Alba Bark Extract Glycine Soja Sterols Allantoin Tocopheryl Acetate Hydrolyzed Soy Protein Palmitoyl Tripeptide-1 Tribehenin Caprylyl Glycol Dipeptide-2 Polygonum Cuspidatum Root Extract PEG-10 Phytosterol PEG-8 Magnesium Aluminum Silicate Arachidyl Glucoside Chrysin Sodium Acrylates Copolymer Steareth-20 Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Cetearyl Alcohol Coco-Glucoside Hesperidin Methyl Chalcone N-Hydroxysuccinimide Benzoic Acid Water, Dimethicone, Pentaerythrityl These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Bakuchiol is a plant-derived antioxidant from the seeds of the Psoralea corylifolia plant. It has antimicrobial, emollient, skin conditioning, and antioxidant properties. You'll likely see it called a "retinol replacement" but the two are technically not related. This is because bakuchiol is able to flip many of the same switches in your skin cells to tell them to: 1) produce more collagen (type I, III, and IV) 2) activate the same genes retinoids do Unlike retinoids, this ingredient will not increase photosensitivity and is safe to use during pregnancy (but please still check in with your doctor!). The flagship clinical trial from Dhaliwal et al. 2019 found 0.5% bakuchiol (twice daily) and 0.5% retinol (once daily) reduced wrinkles and hyperpigmentation equally, but bakuchiol had significantly less irritation. Systematic reviews also back this up: Bakuchiol is comparable to retinol for photoaging but with better tolerability. It also has mild antibacterial properties against Cutibacterium acnes and antifungal activity in vitro against Candida and dermatophytes. The reason bakuchiol works well is due to its structure; it is a meroterpene phenol, or a hybrid molecule. The phenol half acts as an antioxidant while the terpene half is fat-loving. This helps the molecule slip through the skin barrier. This ingredient is usually used between 0.5-2%. Only one case of contact dermatitis has ever been reported for this ingredient. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Dipotassium Glycyrrhizate comes from licorice root. Extracts of licorice have demonstrated to have antibacterial, anti‐inflammatory, antiviral, antioxidant properties. One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs. Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties. Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this. Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation. Licorice root is native to Southern Europe and Asia. It has been used in traditional Chinese medicine