Peptide Skincare & BeautySkin science and ingredient guides

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Isa Knox LXNEW Platinum Sculpting Night Cream Versus DRMTLGY Peptide Night Cream

Isa Knox LXNEW Platinum Sculpting Night Cream Versus DRMTLGY Peptide Night Cream Detailed comparison of Isa Knox LXNEW Platinum Sculpting Night Cream versus DRMTLGY Peptide Night Cream. This anti-aging night moisturizer is formulated around Panthenol and Madec

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Isa Knox LXNEW Platinum Sculpting Night Cream Versus DRMTLGY Peptide Night Cream Detailed comparison of Isa Knox LXNEW Platinum Sculpting Night Cream versus DRMTLGY Peptide Night Cream. This anti-aging night moisturizer is formulated around Panthenol and Madecassoside to soften the look of wrinkles and hydrate skin. This anti-aging night moisturizer is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tripeptide-5 to soften the look of wrinkles. Water Glycerin Butylene Glycol Caprylic/Capric Triglyceride Cyclopentasiloxane Hydrogenated Polydecene Neopentyl Glycol Dicaprate C14-22 Alcohols Dimethicone Pentaerythrityl Tetraethylhexanoate Glyceryl Stearate Butyrospermum Parkii Butter 1,2-Hexanediol Betaine PEG-100 Stearate C12-20 Alkyl Glucoside Panthenol Silica Ammonium Acryloyldimethyltaurate/Vp Copolymer Polyacrylate-13 Parfum Acrylates/C10-30 Alkyl Acrylate Crosspolymer Tromethamine Beheneth-20 Stearyl Glycyrrhetinate Polyisobutene CI 77891 Mica Cedrol Madecassoside Coco-Caprylate/Caprate Adenosine Cetearyl Alcohol Arachidyl Alcohol Squalane Trisodium EDTA CI 77491 Polysorbate 20 Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate Behenyl Alcohol Sorbitan Isostearate Palmitoyl Glycine Arachidyl Glucoside Hydrogenated Lecithin Magnolia Obovata Bark Extract Ceramide NP Adansonia Digitata Fruit Extract Hibiscus Sabdariffa Flower Extract Cholesterol Stearic Acid Carbomer Glucose Xanthan Gum Water, Glycerin, Butylene Glycol, Caprylic/Capric Triglyceride, Cyclopentasiloxane, Hydrogenated Polydecene, Neopentyl Glycol Dicaprate, C14-22 Alcohols, Dimethicone, Pentaerythrityl Tetraethylhexanoate, Glyceryl Stearate, Butyrospermum Parkii Butter, 1,2-Hexanediol, Betaine, PEG-100 Stearate, C12-20 Alkyl Glucoside, Panthenol, Silica, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Polyacrylate-13, Parfum, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Beheneth-20, Stearyl Glycyrrhetinate, Polyisobutene, CI 77891, Mica, Cedrol, Madecassoside, Coco-Caprylate/Caprate, Adenosine, Cetearyl Alcohol, Arachidyl Alcohol, Squalane, Trisodium EDTA, CI 77491, Polysorbate 20, Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate, Behenyl Alcohol, Sorbitan Isostearate, Palmitoyl Glycine, Arachidyl Glucoside, Hydrogenated Lecithin, Magnolia Obovata Bark Extract, Ceramide NP, Adansonia Digitata Fruit Extract, Hibiscus Sabdariffa Flower Extract, Cholesterol, Stearic Acid, Carbomer, Glucose, Xanthan Gum Propanediol C12-15 Alkyl Benzoate Isopropyl Palmitate Undecane Cetyl Alcohol Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine Palmitoyl Tripeptide-1 Palmitoyl Tripeptide-5 Palmitoyl Tetrapeptide-7 Trifluoroacetyl Tripeptide-2 Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate Ceramide AP Ceramide EOP Phytosphingosine Tridecane Allantoin Tocopherol Glycol Distearate Potassium Cetyl Phosphate Ethylhexylglycerin Dextran Magnesium Chloride Phenoxyethanol Disodium EDTA Sodium Hydroxide Sodium Lauroyl Lactylate Water, Glyceryl Stearate, Propanediol, C12-15 Alkyl Benzoate, Glycerin, Isopropyl Palmitate, Undecane, Butyrospermum Parkii Butter, Caprylic/Capric Triglyceride, Cetyl Alcohol, Dimethicone, PEG-100 Stearate, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Palmitoyl Tetrapeptide-7, Trifluoroacetyl Tripeptide-2, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Ceramide NP, Ceramide AP, Ceramide EOP, P These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products. As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied. It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin. A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. This ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients. Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL). In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!). Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo. Shea butter also contains vitamins A and E which may contribute to antioxidant activity. While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement. This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize. Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss. Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid. In practice, that translates to a long shelf life and a consistently elegant skin feel. While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns. Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or