ISDIN Flavo-C Serum Versus Paula's Choice 25% Vitamin C + Glutathione Clinical Serum

ISDIN Flavo-C Serum Versus Paula's Choice 25% Vitamin C + Glutathione Clinical Serum Detailed comparison of ISDIN Flavo-C Serum versus Paula's Choice 25% Vitamin C + Glutathione Clinical Serum. This anti-aging serum is formulated around Ginkgo Biloba Leaf Extract and Ascorbic Acid to soften the look of wrinkles and brighten dull-looking skin. This brightening serum is formulated around Tetrahexyldecyl Ascorbate and Ascorbyl Glucoside to brighten dull-looking skin and fade the look of dark spots. Propylene Glycol Water Ginkgo Biloba Leaf Extract Ascorbic Acid Polysorbate 20 1,2-Hexanediol Polysorbate 80 Phenoxyethanol Lactic Acid Sodium Hydroxide Propylene Glycol, Water, Ginkgo Biloba Leaf Extract, Ascorbic Acid, Polysorbate 20, 1,2-Hexanediol, Polysorbate 80, Phenoxyethanol, Lactic Acid, Sodium Hydroxide Tetrahexyldecyl Ascorbate Dimethicone Glycerin C9-12 Alkane Ascorbyl Glucoside Silica Pyrus Malus Fruit Extract Hydrogenated Lecithin Polyglyceryl-6 Polyricinoleate Acrylates/C10-30 Alkyl Acrylate Crosspolymer Xanthan Gum Oryza Sativa Bran Extract Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Cetyl Alcohol Caprylyl Glycol Lysine Carboxymethyl Cysteinate Coco-Caprylate/Caprate Tocopherol Glutathione Sodium Citrate Sodium Phytate Hexylene Glycol Ethylhexylglycerin Helianthus Annuus Seed Extract Urea Mannitol Caprylic/Capric Triglyceride Sodium PCA Rosmarinus Officinalis Leaf Extract Polysorbate 60 Sorbitan Isostearate Trehalose Glucose Vanilla Planifolia Fruit Extract Polyquaternium-51 Ergothioneine Triacetin Sodium Hyaluronate Water, Tetrahexyldecyl Ascorbate, Dimethicone, Glycerin, C9-12 Alkane, Ascorbyl Glucoside, Silica, Pyrus Malus Fruit Extract, Hydrogenated Lecithin, Polyglyceryl-6 Polyricinoleate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Xanthan Gum, Oryza Sativa Bran Extract, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Cetyl Alcohol, Caprylyl Glycol, Lysine Carboxymethyl Cysteinate, Coco-Caprylate/Caprate, Tocopherol, Glutathione, Sodium Citrate, Sodium Phytate, Hexylene Glycol, Ethylhexylglycerin, Helianthus Annuus Seed Extract, Urea, Mannitol, Caprylic/Capric Triglyceride, Sodium PCA, Rosmarinus Officinalis Leaf Extract, Polysorbate 60, Sorbitan Isostearate, Trehalose, Ascorbic Acid, Glucose, Vanilla Planifolia Fruit Extract, Polyquaternium-51, Ergothioneine, Triacetin, Sodium Hyaluronate, Phenoxyethanol Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Ascorbic Acid is is pure Vitamin C and is the biologically active form used directly by skin. Not only is vitamin C great for your overall health and immune system, but it also has plenty of benefits for your skin. It is best supported by academic literature for: Topical vitamin C has been shown to help neutralize oxidative stress from UV and pollution, helping to improve photoaging and hyperpigmentation when used consistently. One clinical study found that using 5% topical vitamin C for six months improved signs of photodamaged skin, both on the surface and in the deeper structural layers of the skin. While vitamin C doesn’t replace sunscreen, studies show it can boost photoprotection when combined with Vitamin E and ferulic acid. These two ingredients help improve stability and protective effects. The big downside of this ingredient is formulation difficulty. Vitamin C is prone to oxidation and doesn't penetrate the skin unless formulated correctly. Research found that vitamin C absorbs into the skin best at a low pH (< 3.5) with about 20% being the upper limit for effective absorption. Skin levels can saturate after repeated application; this means your skin won’t keep absorbing more once it’s full of vitamin C. This is why more isn’t always better with vitamin C and why very high concentrations don’t necessarily give extra benefits. Ascorbic acid generally works well with many skincare ingredients but can be irritating when combined with other active ingredients. Strong oxidizing acne treatments like benzoyl peroxide can reduce the effectiveness of vitamin C if they are used at the same time; they are often recommended for use at different times of day. Read more about other types of Vitamin C: Foods rich with vitamin C include oranges, strawberries, broccoli, bell peppers, and more. When consuming Vitamin C, your skin receives a portion of the nutrients. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive. Another perk of this ingredient is that it stays functional across a wide pH range (3-10). You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own. Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU. Safety-wise, the fear mongering does not hold up to the