Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Kiehl's Fast Release Wrinkle-Reducing 0.3% Retinol Night Serum Versus Peter Thomas Roth PRO Strength Retinoid Peptide Serum

Kiehl's Fast Release Wrinkle-Reducing 0.3% Retinol Night Serum Versus Peter Thomas Roth PRO Strength Retinoid Peptide Serum Detailed comparison of Kiehl's Fast Release Wrinkle-Reducing 0.3% Retinol Night Serum versus Peter Thomas Roth PRO Strength Retinoid Pep

This source-based comparison does not add ratings or recommend a winner.

Kiehl's Fast Release Wrinkle-Reducing 0.3% Retinol Night Serum Versus Peter Thomas Roth PRO Strength Retinoid Peptide Serum Detailed comparison of Kiehl's Fast Release Wrinkle-Reducing 0.3% Retinol Night Serum versus Peter Thomas Roth PRO Strength Retinoid Peptide Serum. This anti-aging serum is formulated around Panthenol and Adenosine to soften the look of wrinkles and fade the look of dark spots. This anti-aging serum is formulated around Hydroxypinacolone Retinoate and Ceramide NP to soften the look of wrinkles and refine skin texture. Water Glycerin Propanediol Butylene Glycol Glycereth-26 Panthenol 1,2-Hexanediol Polyglycerin-3 C12-14 Pareth-12 Phenoxyethanol Caprylyl Glycol Ammonium Acryloyldimethyltaurate/Vp Copolymer Betaine Xanthan Gum Ethylhexylglycerin Adenosine Carbomer Glyceryl Acrylate/Acrylic Acid Copolymer Tromethamine Glycereth-25 PCA Isostearate T-Butyl Alcohol Tocopherol Water, Glycerin, Propanediol, Butylene Glycol, Glycereth-26, Panthenol, 1,2-Hexanediol, Polyglycerin-3, C12-14 Pareth-12, Phenoxyethanol, Caprylyl Glycol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Betaine, Xanthan Gum, Ethylhexylglycerin, Adenosine, Carbomer, Glyceryl Acrylate/Acrylic Acid Copolymer, Tromethamine, Glycereth-25 PCA Isostearate, T-Butyl Alcohol, Tocopherol C9-12 Alkane Dimethicone Isononyl Isononanoate Dimethyl Isosorbide Trisiloxane Cyclopentasiloxane Polysilicone-11 Coco-Caprylate/Caprate Caprylic/Capric Triglyceride Hydroxypinacolone Retinoate Palmitoyl Hexapeptide-14 Ceramide NP Helianthus Annuus Seed Extract Hordeum Vulgare Extract Cucumis Sativus Extract Laminaria Ochroleuca Extract Zingiber Officinale Root Extract Phytosteryl Canola Glycerides Sodium Hyaluronate Sodium PCA Squalane Lecithin Linoleic Acid Oleic Acid Palmitic Acid Stearic Acid Hydroxystearic Acid Triolein Bisabolol Ethylhexyl Hydroxystearate Ethoxydiglycol Mica C9-12 Alkane, Dimethicone, Isononyl Isononanoate, Dimethyl Isosorbide, Trisiloxane, Cyclopentasiloxane, Polysilicone-11, Coco-Caprylate/Caprate, Caprylic/Capric Triglyceride, Hydroxypinacolone Retinoate, Palmitoyl Hexapeptide-14, Ceramide NP, Helianthus Annuus Seed Extract, Hordeum Vulgare Extract, Cucumis Sativus Extract, Laminaria Ochroleuca Extract, Zingiber Officinale Root Extract, Phytosteryl Canola Glycerides, Sodium Hyaluronate, Sodium PCA, Squalane, Tocopherol, Lecithin, Linoleic Acid, Oleic Acid, Palmitic Acid, Stearic Acid, Hydroxystearic Acid, Triolein, Bisabolol, Ethylhexyl Hydroxystearate, Ethoxydiglycol, Ethylhexylglycerin, Water, Mica, Phenoxyethanol These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that: The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure. Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive. Another perk of this ingredient is that it stays functional across a wide pH range (3-10). You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own. Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU. Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages. Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon. Tocopherol is a fat-soluble antioxidant known as Vitamin E. You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells. Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes. It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks. This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage. This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out the