Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Kiehl's Micro-Dose Anti-Aging Retinol Serum with Ceramides and Peptide Versus Celimax The Vita-A Retinol Shot Tightening Serum

Kiehl's Micro-Dose Anti-Aging Retinol Serum with Ceramides and Peptide Versus Celimax The Vita-A Retinol Shot Tightening Serum Detailed comparison of Kiehl's Micro-Dose Anti-Aging Retinol Serum with Ceramides and Peptide versus Celimax The Vita-A Retinol Shot

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Kiehl's Micro-Dose Anti-Aging Retinol Serum with Ceramides and Peptide Versus Celimax The Vita-A Retinol Shot Tightening Serum Detailed comparison of Kiehl's Micro-Dose Anti-Aging Retinol Serum with Ceramides and Peptide versus Celimax The Vita-A Retinol Shot Tightening Serum. This anti-aging serum is formulated around Niacinamide and Ceramide NP to soften the look of wrinkles and refine skin texture. This anti-aging serum is formulated around Retinol and Palmitoyl Pentapeptide-4 to soften the look of wrinkles and refine skin texture. Water Glycerin Butylene Glycol Pentylene Glycol Niacinamide Cetyl Alcohol Isohexadecane Isononyl Isononanoate Diisopropyl Sebacate 2-Oleamido-1,3-Octadecanediol 4-T-Butylcyclohexanol Acetyl Dipeptide-1 Cetyl Ester Adenosine Ceramide NP Hydroxypalmitoyl Sphinganine Lauroyl Lysine Octyldodecanol Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate Sodium Chloride Sodium Hyaluronate Sodium Hydroxide Trisodium Ethylenediamine Disuccinate Retinol Tocopherol Dicaprylyl Ether Ammonium Polyacryloyldimethyl Taurate Behenyl Alcohol Caprylyl Glycol Carbomer Cetearyl Alcohol Cetearyl Glucoside Glycine Soja Oil Helianthus Annuus Seed Oil Hydroxyethylcellulose Lecithin Phenethyl Alcohol Poloxamer 188 Polycaprolactone Sorbitan Laurate Steareth-100 CI 40800 Chlorphenesin Phenoxyethanol Water, Glycerin, Butylene Glycol, Pentylene Glycol, Niacinamide, Cetyl Alcohol, Isohexadecane, Isononyl Isononanoate, Diisopropyl Sebacate, 2-Oleamido-1,3-Octadecanediol, 4-T-Butylcyclohexanol, Acetyl Dipeptide-1 Cetyl Ester, Adenosine, Ceramide NP, Hydroxypalmitoyl Sphinganine, Lauroyl Lysine, Octyldodecanol, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Sodium Chloride, Sodium Hyaluronate, Sodium Hydroxide, Trisodium Ethylenediamine Disuccinate, Retinol, Tocopherol, Dicaprylyl Ether, Ammonium Polyacryloyldimethyl Taurate, Behenyl Alcohol, Caprylyl Glycol, Carbomer, Cetearyl Alcohol, Cetearyl Glucoside, Glycine Soja Oil, Helianthus Annuus Seed Oil, Hydroxyethylcellulose, Lecithin, Phenethyl Alcohol, Poloxamer 188, Polycaprolactone, Sorbitan Laurate, Steareth-100, CI 40800, Chlorphenesin, Phenoxyethanol Methylpropanediol 1,2-Hexanediol Caprylic/Capric Triglyceride Panthenol Polypropylsilsesquioxane C14-22 Alcohols Glyceryl Stearates Ammonium Acryloyldimethyltaurate/Vp Copolymer Hydrolyzed Sponge Acrylates/C10-30 Alkyl Acrylate Crosspolymer Retinol 0.1% Allantoin Arginine Undecane Xanthan Gum Ethylhexylglycerin C12-20 Alkyl Glucoside Lauryl Glucoside Polyglyceryl-6 Laurate Tridecane Disodium EDTA Daucus Carota Sativa Root Extract Myristyl Glucoside Glyceryl Acrylate/Acrylic Acid Copolymer Pvm/Ma Copolymer Beta-Carotene Glucose Tripeptide-1 Palmitoyl Tripeptide-1 Nonapeptide-1 Hexapeptide-9 Dipeptide-2 Copper Tripeptide-1 Acetyl Tetrapeptide-5 Acetyl Hexapeptide-8 Palmitoyl Pentapeptide-4 Water, Methylpropanediol, Glycerin, 1,2-Hexanediol, Caprylic/Capric Triglyceride, Panthenol, Polypropylsilsesquioxane, C14-22 Alcohols, Glyceryl Stearates, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Hydrolyzed Sponge, Helianthus Annuus Seed Oil, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tocopherol, Retinol 0.1%, Allantoin, Arginine, Undecane, Xanthan Gum, Ethylhexylglycerin, C12-20 Alkyl Glucoside, Lauryl Glucoside, Polyglyceryl-6 Laurate, Adenosine, Tridecane, Disodium EDTA, Daucus Carota Sativa Root Extract, Myristyl Glucoside, Glyceryl Acrylate/Acrylic Acid Copolymer, Pvm/Ma Copolymer, Butylene Glycol, Beta-Carotene, Glucose, Tripeptide-1, Palmitoyl Tripeptide-1, Nonapeptide- These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent. The way it works is fairly well mapped out: Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going. The clinical backing is pretty solid too. A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months. A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration. On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses. This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization. Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Helianthus Annuus Seed Oil is a plant oil derived from the seeds of a sunflower. It is rich in fatty acids, primarily linoleic acid and oleic