Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Kiehl's Micro-Dose Anti-Aging Retinol Serum with Ceramides and Peptide Versus Clinique Smart Clinical Repair Wrinkle Correcting Cream

Kiehl's Micro-Dose Anti-Aging Retinol Serum with Ceramides and Peptide Versus Clinique Smart Clinical Repair Wrinkle Correcting Cream Detailed comparison of Kiehl's Micro-Dose Anti-Aging Retinol Serum with Ceramides and Peptide versus Clinique Smart Clinical R

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Kiehl's Micro-Dose Anti-Aging Retinol Serum with Ceramides and Peptide Versus Clinique Smart Clinical Repair Wrinkle Correcting Cream Detailed comparison of Kiehl's Micro-Dose Anti-Aging Retinol Serum with Ceramides and Peptide versus Clinique Smart Clinical Repair Wrinkle Correcting Cream. This anti-aging serum is formulated around Niacinamide and Ceramide NP to soften the look of wrinkles and refine skin texture. This anti-aging moisturizer is formulated around Acetyl Hexapeptide-8 and Acetyl Octapeptide-3 to soften the look of wrinkles and refine skin texture. Water Glycerin Butylene Glycol Pentylene Glycol Niacinamide Cetyl Alcohol Isohexadecane Isononyl Isononanoate Diisopropyl Sebacate 2-Oleamido-1,3-Octadecanediol 4-T-Butylcyclohexanol Acetyl Dipeptide-1 Cetyl Ester Adenosine Ceramide NP Hydroxypalmitoyl Sphinganine Lauroyl Lysine Octyldodecanol Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate Sodium Chloride Sodium Hyaluronate Sodium Hydroxide Trisodium Ethylenediamine Disuccinate Retinol Tocopherol Dicaprylyl Ether Ammonium Polyacryloyldimethyl Taurate Behenyl Alcohol Caprylyl Glycol Carbomer Cetearyl Alcohol Cetearyl Glucoside Glycine Soja Oil Helianthus Annuus Seed Oil Hydroxyethylcellulose Lecithin Phenethyl Alcohol Poloxamer 188 Polycaprolactone Sorbitan Laurate Steareth-100 CI 40800 Chlorphenesin Phenoxyethanol Water, Glycerin, Butylene Glycol, Pentylene Glycol, Niacinamide, Cetyl Alcohol, Isohexadecane, Isononyl Isononanoate, Diisopropyl Sebacate, 2-Oleamido-1,3-Octadecanediol, 4-T-Butylcyclohexanol, Acetyl Dipeptide-1 Cetyl Ester, Adenosine, Ceramide NP, Hydroxypalmitoyl Sphinganine, Lauroyl Lysine, Octyldodecanol, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Sodium Chloride, Sodium Hyaluronate, Sodium Hydroxide, Trisodium Ethylenediamine Disuccinate, Retinol, Tocopherol, Dicaprylyl Ether, Ammonium Polyacryloyldimethyl Taurate, Behenyl Alcohol, Caprylyl Glycol, Carbomer, Cetearyl Alcohol, Cetearyl Glucoside, Glycine Soja Oil, Helianthus Annuus Seed Oil, Hydroxyethylcellulose, Lecithin, Phenethyl Alcohol, Poloxamer 188, Polycaprolactone, Sorbitan Laurate, Steareth-100, CI 40800, Chlorphenesin, Phenoxyethanol Isostearyl Neopentanoate Glyceryl Stearate PEG-100 Stearate Dimethicone Acetyl Hexapeptide-8 Acetyl Octapeptide-3 Aminopropyl Ascorbyl Phosphate Palmitoyl Tetrapeptide-7 Algae Extract Palmitoyl Hexapeptide-12 Sigesbeckia Orientalis Extract Whey Protein Dipeptide Diaminobutyroyl Benzylamide Diacetate Acetyl Glucosamine Caffeine Palmitoyl Tripeptide-1 Glycine Soja Seed Extract Tocopheryl Acetate Petrolatum Glycereth-26 Acrylates/C10-30 Alkyl Acrylate Crosspolymer Tromethamine Glyceryl Polymethacrylate PEG-8 Polysorbate 20 Hexylene Glycol Polysorbate 80 Acrylamide/Sodium Acryloyldimethyltaurate Copolymer Sorbitan Oleate Sodium Citrate Disodium EDTA Potassium Sorbate Sodium Benzoate Water, Glycerin, Isostearyl Neopentanoate, Butylene Glycol, Glyceryl Stearate, PEG-100 Stearate, Dimethicone, Cetearyl Alcohol, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Aminopropyl Ascorbyl Phosphate, Palmitoyl Tetrapeptide-7, Algae Extract, Sodium Hyaluronate, Palmitoyl Hexapeptide-12, Sigesbeckia Orientalis Extract, Whey Protein, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetyl Glucosamine, Caffeine, Palmitoyl Tripeptide-1, Glycine Soja Seed Extract, Cetearyl Glucoside, Tocopheryl Acetate, Isohexadecane, Petrolatum, Caprylyl Glycol, Glycereth-26, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Glyceryl Polymethacrylate, PEG-8, Polysorbate 20, Hexylene Glycol, Polysorbate Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier. Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient. It plays several roles in a formula: Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products. Multiple assessments have found it to be non-irritating and non-sensitizing to most people. However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers. Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy. Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans. Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients. This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain len