Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Kiehl's Micro-Dose Anti-Aging Retinol Serum with Ceramides and Peptide Versus Dr. Dennis Gross Skincare Advanced Retinol + Ferulic Texture Renewal Serum

Kiehl's Micro-Dose Anti-Aging Retinol Serum with Ceramides and Peptide Versus Dr. Dennis Gross Skincare Advanced Retinol + Ferulic Texture Renewal Serum Detailed comparison of Kiehl's Micro-Dose Anti-Aging Retinol Serum with Ceramides and Peptide versus Dr. De

This source-based comparison does not add ratings or recommend a winner.

Kiehl's Micro-Dose Anti-Aging Retinol Serum with Ceramides and Peptide Versus Dr. Dennis Gross Skincare Advanced Retinol + Ferulic Texture Renewal Serum Detailed comparison of Kiehl's Micro-Dose Anti-Aging Retinol Serum with Ceramides and Peptide versus Dr. Dennis Gross Skincare Advanced Retinol + Ferulic Texture Renewal Serum. This anti-aging serum is formulated around Niacinamide and Ceramide NP to soften the look of wrinkles and refine skin texture. This smoothing serum is formulated around Lactic Acid and Retinol to refine skin texture and soften the look of wrinkles. Water Glycerin Butylene Glycol Pentylene Glycol Niacinamide Cetyl Alcohol Isohexadecane Isononyl Isononanoate Diisopropyl Sebacate 2-Oleamido-1,3-Octadecanediol 4-T-Butylcyclohexanol Acetyl Dipeptide-1 Cetyl Ester Adenosine Ceramide NP Hydroxypalmitoyl Sphinganine Lauroyl Lysine Octyldodecanol Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate Sodium Chloride Sodium Hyaluronate Sodium Hydroxide Trisodium Ethylenediamine Disuccinate Retinol Tocopherol Dicaprylyl Ether Ammonium Polyacryloyldimethyl Taurate Behenyl Alcohol Caprylyl Glycol Carbomer Cetearyl Alcohol Cetearyl Glucoside Glycine Soja Oil Helianthus Annuus Seed Oil Hydroxyethylcellulose Lecithin Phenethyl Alcohol Poloxamer 188 Polycaprolactone Sorbitan Laurate Steareth-100 CI 40800 Chlorphenesin Phenoxyethanol Water, Glycerin, Butylene Glycol, Pentylene Glycol, Niacinamide, Cetyl Alcohol, Isohexadecane, Isononyl Isononanoate, Diisopropyl Sebacate, 2-Oleamido-1,3-Octadecanediol, 4-T-Butylcyclohexanol, Acetyl Dipeptide-1 Cetyl Ester, Adenosine, Ceramide NP, Hydroxypalmitoyl Sphinganine, Lauroyl Lysine, Octyldodecanol, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Sodium Chloride, Sodium Hyaluronate, Sodium Hydroxide, Trisodium Ethylenediamine Disuccinate, Retinol, Tocopherol, Dicaprylyl Ether, Ammonium Polyacryloyldimethyl Taurate, Behenyl Alcohol, Caprylyl Glycol, Carbomer, Cetearyl Alcohol, Cetearyl Glucoside, Glycine Soja Oil, Helianthus Annuus Seed Oil, Hydroxyethylcellulose, Lecithin, Phenethyl Alcohol, Poloxamer 188, Polycaprolactone, Sorbitan Laurate, Steareth-100, CI 40800, Chlorphenesin, Phenoxyethanol Propylene Glycol Dimethyl Isosorbide Polyglyceryl-10 Laurate Ethoxydiglycol Lactic Acid Hydroxypropyl Starch Phosphate Mandelic Acid Bakuchiol Nephelium Lappaceum Leaf Extract Ferulic Acid Squalane Linoleic Acid Salicylic Acid Salix Alba Bark Extract Phospholipids Soy Isoflavones Saccharide Isomerate Ubiquinone Sodium PCA Hexylresorcinol Quercetin Morus Alba Bark Extract Panthenol Glycolic Acid Maltodextrin Xanthan Gum Leuconostoc/Radish Root Ferment Filtrate Caprylic/Capric Triglyceride Potassium Hydroxide Polysorbate 20 Sodium Phytate Citric Acid Sodium Citrate Sodium Benzoate Potassium Sorbate Water, Propylene Glycol, Dimethyl Isosorbide, Polyglyceryl-10 Laurate, Glycerin, Ethoxydiglycol, Lactic Acid, Hydroxypropyl Starch Phosphate, Mandelic Acid, Retinol, Bakuchiol, Nephelium Lappaceum Leaf Extract, Ferulic Acid, Squalane, Linoleic Acid, Salicylic Acid, Salix Alba Bark Extract, Phospholipids, Soy Isoflavones, Sodium Hyaluronate, Saccharide Isomerate, Ubiquinone, Sodium PCA, Hexylresorcinol, Quercetin, Adenosine, Morus Alba Bark Extract, Panthenol, Glycolic Acid, Maltodextrin, Xanthan Gum, Leuconostoc/Radish Root Ferment Filtrate, Caprylic/Capric Triglyceride, Potassium Hydroxide, Polysorbate 20, Sodium Phytate, Citric Acid, Sodium Citrate, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent. The way it works is fairly well mapped out: Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going. The clinical backing is pretty solid too. A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months. A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration. On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses. This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization. Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive. Another perk of this ingredient