Kiehl's Micro-Dose Anti-Aging Retinol Serum with Ceramides and Peptide Versus Neutrogena Ageless Intensives Anti-Wrinkle Deep Wrinkle Serum

Kiehl's Micro-Dose Anti-Aging Retinol Serum with Ceramides and Peptide Versus Neutrogena Ageless Intensives Anti-Wrinkle Deep Wrinkle Serum Detailed comparison of Kiehl's Micro-Dose Anti-Aging Retinol Serum with Ceramides and Peptide versus Neutrogena Ageless Intensives Anti-Wrinkle Deep Wrinkle Serum. This anti-aging serum is formulated around Niacinamide and Ceramide NP to soften the look of wrinkles and refine skin texture. This anti-aging serum is formulated around Squalane and Retinol to soften the look of wrinkles and refine skin texture. Water Glycerin Butylene Glycol Pentylene Glycol Niacinamide Cetyl Alcohol Isohexadecane Isononyl Isononanoate Diisopropyl Sebacate 2-Oleamido-1,3-Octadecanediol 4-T-Butylcyclohexanol Acetyl Dipeptide-1 Cetyl Ester Adenosine Ceramide NP Hydroxypalmitoyl Sphinganine Lauroyl Lysine Octyldodecanol Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate Sodium Chloride Sodium Hyaluronate Sodium Hydroxide Trisodium Ethylenediamine Disuccinate Retinol Tocopherol Dicaprylyl Ether Ammonium Polyacryloyldimethyl Taurate Behenyl Alcohol Caprylyl Glycol Carbomer Cetearyl Alcohol Cetearyl Glucoside Glycine Soja Oil Helianthus Annuus Seed Oil Hydroxyethylcellulose Lecithin Phenethyl Alcohol Poloxamer 188 Polycaprolactone Sorbitan Laurate Steareth-100 CI 40800 Chlorphenesin Phenoxyethanol Water, Glycerin, Butylene Glycol, Pentylene Glycol, Niacinamide, Cetyl Alcohol, Isohexadecane, Isononyl Isononanoate, Diisopropyl Sebacate, 2-Oleamido-1,3-Octadecanediol, 4-T-Butylcyclohexanol, Acetyl Dipeptide-1 Cetyl Ester, Adenosine, Ceramide NP, Hydroxypalmitoyl Sphinganine, Lauroyl Lysine, Octyldodecanol, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Sodium Chloride, Sodium Hyaluronate, Sodium Hydroxide, Trisodium Ethylenediamine Disuccinate, Retinol, Tocopherol, Dicaprylyl Ether, Ammonium Polyacryloyldimethyl Taurate, Behenyl Alcohol, Caprylyl Glycol, Carbomer, Cetearyl Alcohol, Cetearyl Glucoside, Glycine Soja Oil, Helianthus Annuus Seed Oil, Hydroxyethylcellulose, Lecithin, Phenethyl Alcohol, Poloxamer 188, Polycaprolactone, Sorbitan Laurate, Steareth-100, CI 40800, Chlorphenesin, Phenoxyethanol Cyclopentasiloxane Dipropylene Glycol Dimethicone Adipic Acid/Diglycol Crosspolymer Dimethicone/PEG-10/15 Crosspolymer Dimethicone/Vinyl Dimethicone Crosspolymer Squalane Bisabolol Ethylhexylglycerin Caprylic/Capric Triglyceride Sodium Citrate Erythorbic Acid Dipotassium Glycyrrhizate BHT Avena Sativa Kernel Extract Water, Cyclopentasiloxane, Dipropylene Glycol, Dimethicone, Isononyl Isononanoate, Adipic Acid/Diglycol Crosspolymer, Dimethicone/PEG-10/15 Crosspolymer, Dimethicone/Vinyl Dimethicone Crosspolymer, Squalane, Glycerin, Bisabolol, Ethylhexylglycerin, Sodium Chloride, Caprylic/Capric Triglyceride, Sodium Citrate, Erythorbic Acid, Dipotassium Glycyrrhizate, BHT, Retinol, Tocopherol, Avena Sativa Kernel Extract Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Isononyl Isononanoate is a synthetic skin-conditioner and texture enhancer. It is created from nonanoic acid, a fatty acid found in cocoa and lavender oil. As an emollient, Isononyl Isononanoate helps keep your skin soft and smooth. This is because emollients create a barrier on the skin to trap moisture in. Isononyl Isononanoate helps give products a velvet feel and improves spreadability. Retinol is one of the most studied anti-aging ingredients in skincare (and for good reason!). It's a form of vitamin A that your skin converts into Retinoic Acid, the active molecule that actually does the work in your cells. That conversion happens in two steps: your skin first turns Retinol into Retinaldehyde (also called Retinal), then turns Retinaldehyde into Retinoic Acid. Retinol is converted to biologically active retinoic acid via retinaldehyde by dehydrogenases in a two-step oxidation process. Each step is a little "upgrade" toward the active form which is part of why Retinol is gentler than prescription Retinoic Acid; your skin does the work gradually. This also explains where Retinol sits in the retinoid family. Here is the retinoid family ranked roughly by strength: Retinyl Esters (like Retinyl Palmitate) < Retinol < Retinaldehyde < Retinoic Acid. Retinoid activity increases in that order, while tolerance runs in reverse; retinyl esters are the gentlest and retinoic acid the most irritating. The more conversion steps an ingredient needs, the gentler (and slower) it tends to be, so Retinol lands in a nice middle spot. It's more effective than the esters, gentler than prescription options. Once it becomes Retinoic Acid, it binds to receptors inside your cells' nuclei (called RARs and RXRs). These receptor pairs bind to specific DNA motifs called retinoic acid response elements and act like switches that turn certain genes on or off. In practice, this means a few things happen in a formula. It: That last two are w