Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Kiehl's Micro-Dose Anti-Aging Retinol Serum with Ceramides and Peptide Versus Paula's Choice 1% Retinol Treatment

Kiehl's Micro-Dose Anti-Aging Retinol Serum with Ceramides and Peptide Versus Paula's Choice 1% Retinol Treatment Detailed comparison of Kiehl's Micro-Dose Anti-Aging Retinol Serum with Ceramides and Peptide versus Paula's Choice 1% Retinol Treatment EU. This

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Kiehl's Micro-Dose Anti-Aging Retinol Serum with Ceramides and Peptide Versus Paula's Choice 1% Retinol Treatment Detailed comparison of Kiehl's Micro-Dose Anti-Aging Retinol Serum with Ceramides and Peptide versus Paula's Choice 1% Retinol Treatment EU. This anti-aging serum is formulated around Niacinamide and Ceramide NP to soften the look of wrinkles and refine skin texture. This anti-aging treatment is formulated around Retinol and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture. Water Glycerin Butylene Glycol Pentylene Glycol Niacinamide Cetyl Alcohol Isohexadecane Isononyl Isononanoate Diisopropyl Sebacate 2-Oleamido-1,3-Octadecanediol 4-T-Butylcyclohexanol Acetyl Dipeptide-1 Cetyl Ester Adenosine Ceramide NP Hydroxypalmitoyl Sphinganine Lauroyl Lysine Octyldodecanol Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate Sodium Chloride Sodium Hyaluronate Sodium Hydroxide Trisodium Ethylenediamine Disuccinate Retinol Tocopherol Dicaprylyl Ether Ammonium Polyacryloyldimethyl Taurate Behenyl Alcohol Caprylyl Glycol Carbomer Cetearyl Alcohol Cetearyl Glucoside Glycine Soja Oil Helianthus Annuus Seed Oil Hydroxyethylcellulose Lecithin Phenethyl Alcohol Poloxamer 188 Polycaprolactone Sorbitan Laurate Steareth-100 CI 40800 Chlorphenesin Phenoxyethanol Water, Glycerin, Butylene Glycol, Pentylene Glycol, Niacinamide, Cetyl Alcohol, Isohexadecane, Isononyl Isononanoate, Diisopropyl Sebacate, 2-Oleamido-1,3-Octadecanediol, 4-T-Butylcyclohexanol, Acetyl Dipeptide-1 Cetyl Ester, Adenosine, Ceramide NP, Hydroxypalmitoyl Sphinganine, Lauroyl Lysine, Octyldodecanol, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Sodium Chloride, Sodium Hyaluronate, Sodium Hydroxide, Trisodium Ethylenediamine Disuccinate, Retinol, Tocopherol, Dicaprylyl Ether, Ammonium Polyacryloyldimethyl Taurate, Behenyl Alcohol, Caprylyl Glycol, Carbomer, Cetearyl Alcohol, Cetearyl Glucoside, Glycine Soja Oil, Helianthus Annuus Seed Oil, Hydroxyethylcellulose, Lecithin, Phenethyl Alcohol, Poloxamer 188, Polycaprolactone, Sorbitan Laurate, Steareth-100, CI 40800, Chlorphenesin, Phenoxyethanol Dimethicone Castor Isostearate Succinate Glyceryl Stearate C12-15 Alkyl Benzoate Dimethicone Crosspolymer PEG-33 Polysorbate 20 Tetrahexyldecyl Ascorbate PEG-100 Stearate Pentaerythrityl Tetraisostearate Polymethylsilsesquioxane Ceramide Ng Palmitoyl Tripeptide-1 Palmitoyl Tetrapeptide-7 Palmitoyl Hexapeptide-12 Dipotassium Glycyrrhizate Glycyrrhiza Glabra Root Extract Avena Sativa Kernel Extract Arctium Lappa Root Extract Morus Alba Root Extract Glycine Soja Sterols Allantoin Tocopheryl Acetate Hydrolyzed Soy Protein Disodium EDTA Tribehenin Ethylhexylglycerin PEG-75 Shea Butter Glycerides PPG-12/Smdi Copolymer PEG-10 Phytosterol PEG-8 Dimethicone PEG-14 Magnesium Aluminum Silicate Arachidyl Glucoside Sclerotium Gum Arachidyl Alcohol Benzoic Acid Water, Dimethicone, Glycerin, Butylene Glycol, Isononyl Isononanoate, Castor Isostearate Succinate, Glyceryl Stearate, C12-15 Alkyl Benzoate, Dimethicone Crosspolymer, PEG-33, Polysorbate 20, Behenyl Alcohol, Tetrahexyldecyl Ascorbate, PEG-100 Stearate, Pentaerythrityl Tetraisostearate, Polymethylsilsesquioxane, Retinol, Ceramide Ng, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Root Extract, Avena Sativa Kernel Extract, Arctium Lappa Root Extract, Morus Alba Root Extract, Glycine Soja Sterols, Lecithin, Allantoin, Tocopheryl Acetate, Hydrolyzed Soy Pr These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acetyl Dipeptide-1 Cetyl Ester is a peptide composed of amino acids arginine and tyrosine. This peptide is considered a neurotransmitter peptide, meaning it has pain-relieving and relaxing properties. It has the ability to calm skin irritation from external factors such as chemical stinging or heat. Neurotransmitter peptides are also often called "botox in a bottle". This is because these peptides have the ability to relax the muscles. Though relaxing the muscles can prevent expression lines (as we have seen in botox), the studies do not show these peptides to be a botox replacement. The effects of this muscle relaxation is also short-term, as opposed to longer-term results from botox. Behenyl Alcohol is a type of fatty alcohol (these are different from the drying, solvent alcohols). Fatty Alcohols have hydrating properties and are most often used as an emollient or to thicken a product. They are usually derived from natural fats and oils; behenyl alcohol is derived from the fats of vegetable oils. Emollients help keep your skin soft and hydrated by creating a film that traps moisture in. In 2000, Behenyl Alcohol was approved by the US as medicine to reduce the duration of cold sores. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (m