Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Kiehl's Ultra Pure High-Potency 1.5% Hyaluronic Acid Serum Versus Hylamide SubQ Skin

Kiehl's Ultra Pure High-Potency 1.5% Hyaluronic Acid Serum Versus Hylamide SubQ Skin Detailed comparison of Kiehl's Ultra Pure High-Potency 1.5% Hyaluronic Acid Serum versus Hylamide SubQ Skin. This hydrating serum is formulated around Sodium Hyaluronate to hy

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Kiehl's Ultra Pure High-Potency 1.5% Hyaluronic Acid Serum Versus Hylamide SubQ Skin Detailed comparison of Kiehl's Ultra Pure High-Potency 1.5% Hyaluronic Acid Serum versus Hylamide SubQ Skin. This hydrating serum is formulated around Sodium Hyaluronate to hydrate skin and strengthen the skin barrier. This anti-aging serum is formulated around Palmitoyl Tripeptide-38 and Sodium Hyaluronate Crosspolymer to soften the look of wrinkles and hydrate skin. Water Glycerin Sodium Hyaluronate Phenoxyethanol Chlorphenesin Tetrasodium Glutamate Diacetate Citric Acid Water, Glycerin, Sodium Hyaluronate, Phenoxyethanol, Chlorphenesin, Tetrasodium Glutamate Diacetate, Citric Acid Hydrolyzed Yeast Extract Pentylene Glycol Tamarindus Indica Seed Gum Sodium Hyaluronate Crosspolymer Palmitoyl Tripeptide-38 Myristoyl Nonapeptide-3 Copper Lysinate/Prolinate Methylglucoside Phosphate Hydrolyzed Sodium Hyaluronate Ahnfeltia Concinna Extract Saccharide Isomerate Polyglucuronic Acid Lactobacillus/Eriodictyon Californicum Ferment Extract Pseudoalteromonas Ferment Extract Phospholipids Lecithin Hydroxypropyl Cyclodextrin Cetyl Hydroxyethylcellulose Polyacrylate Crosspolymer-6 Hexylene Glycol Salicylic Acid Sodium Citrate Sodium Hydroxide Trisodium Ethylenediamine Disuccinate Ethoxydiglycol Leuconostoc/Radish Root Ferment Filtrate Sodium Benzoate Potassium Sorbate Ethylhexylglycerin Caprylyl Glycol Water, Glycerin, Hydrolyzed Yeast Extract, Pentylene Glycol, Tamarindus Indica Seed Gum, Sodium Hyaluronate Crosspolymer, Palmitoyl Tripeptide-38, Myristoyl Nonapeptide-3, Copper Lysinate/Prolinate, Methylglucoside Phosphate, Hydrolyzed Sodium Hyaluronate, Sodium Hyaluronate, Ahnfeltia Concinna Extract, Saccharide Isomerate, Polyglucuronic Acid, Lactobacillus/Eriodictyon Californicum Ferment Extract, Pseudoalteromonas Ferment Extract, Phospholipids, Lecithin, Hydroxypropyl Cyclodextrin, Cetyl Hydroxyethylcellulose, Polyacrylate Crosspolymer-6, Hexylene Glycol, Salicylic Acid, Citric Acid, Sodium Citrate, Sodium Hydroxide, Trisodium Ethylenediamine Disuccinate, Ethoxydiglycol, Leuconostoc/Radish Root Ferment Filtrate, Sodium Benzoate, Potassium Sorbate, Ethylhexylglycerin, Caprylyl Glycol, Phenoxyethanol, Chlorphenesin These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Chlorphenesin is a synthetic preservative. It helps protect a product against bacteria in order to extend shelf life. In most cases, Chlorphenesin is paired with other preservatives such as phenoxyethanol and caprylyl glycol. Chlorphenesin is a biocide. This means it is able to help fight the microorganisms on our skin. It is also able to fight odor-releasing bacteria. Chlorphenesin is soluble in both water and glycerin. Studies show Chlorphenesin is easily absorbed by our skin. You should speak with a skincare professional if you have concerns about using Chlorphenesin. Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes. Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath. However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products. Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH. In skincare formulas, citric acid can: While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants. Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations. Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger. However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humi