Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

La Mer The Concentrate Versus Paula's Choice 1% Retinol Treatment

La Mer The Concentrate Versus Paula's Choice 1% Retinol Treatment Detailed comparison of La Mer The Concentrate versus Paula's Choice 1% Retinol Treatment US. This calming serum is formulated around Laminaria Ochroleuca Extract and Linoleic Acid to calm rednes

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La Mer The Concentrate Versus Paula's Choice 1% Retinol Treatment Detailed comparison of La Mer The Concentrate versus Paula's Choice 1% Retinol Treatment US. This calming serum is formulated around Laminaria Ochroleuca Extract and Linoleic Acid to calm redness and strengthen the skin barrier. This anti-aging treatment is formulated around Retinol and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture. Cyclopentasiloxane Algae Extract Glycerin Dimethicone Polysilicone-11 Isononyl Isononanoate Dimethicone/PEG-10/15 Crosspolymer Cyclohexasiloxane Sesamum Indicum Seed Oil Medicago Sativa Seed Powder Helianthus Annuus Seedcake Prunus Amygdalus Dulcis Seed Meal Eucalyptus Globulus Leaf Oil Sodium Gluconate Copper Gluconate Calcium Gluconate Magnesium Gluconate Zinc Gluconate Tocopheryl Succinate Niacin Sesamum Indicum Seed Powder Water Dimethicone Crosspolymer Laminaria Ochroleuca Extract Triticum Vulgare Flour Lipids Citrus Aurantifolia Peel Extract Crithmum Maritimum Extract Alteromonas Ferment Extract Chlorella Vulgaris Extract Faex Extract Cholesterol Linoleic Acid Tocopherol Tetraacetylphytosphingosine Caprylic/Capric Triglyceride Rosmarinus Officinalis Leaf Oil Ocimum Basilicum Oil Lavandula Angustifolia Oil Lavandula Hybrida Oil Dipropylene Glycol Alcohol Denat. Sodium Citrate Parfum Eugenol Limonene Linalool BHT Phenoxyethanol Potassium Sorbate Cyclopentasiloxane, Algae Extract, Glycerin, Dimethicone, Polysilicone-11, Isononyl Isononanoate, Dimethicone/PEG-10/15 Crosspolymer, Cyclohexasiloxane, Sesamum Indicum Seed Oil, Medicago Sativa Seed Powder, Helianthus Annuus Seedcake, Prunus Amygdalus Dulcis Seed Meal, Eucalyptus Globulus Leaf Oil, Sodium Gluconate, Copper Gluconate, Calcium Gluconate, Magnesium Gluconate, Zinc Gluconate, Tocopheryl Succinate, Niacin, Sesamum Indicum Seed Powder, Water, Dimethicone Crosspolymer, Laminaria Ochroleuca Extract, Triticum Vulgare Flour Lipids, Citrus Aurantifolia Peel Extract, Crithmum Maritimum Extract, Alteromonas Ferment Extract, Chlorella Vulgaris Extract, Faex Extract, Cholesterol, Linoleic Acid, Tocopherol, Tetraacetylphytosphingosine, Caprylic/Capric Triglyceride, Rosmarinus Officinalis Leaf Oil, Ocimum Basilicum Oil, Lavandula Angustifolia Oil, Lavandula Hybrida Oil, Dipropylene Glycol, Alcohol Denat., Sodium Citrate, Parfum, Eugenol, Limonene, Linalool, BHT, Phenoxyethanol, Potassium Sorbate Butylene Glycol Castor Isostearate Succinate Glyceryl Stearate C12-15 Alkyl Benzoate PEG-33 Polysorbate 20 Behenyl Alcohol PEG-100 Stearate Pentaerythrityl Tetraisostearate Polymethylsilsesquioxane Tetrahexyldecyl Ascorbate Retinol Ceramide Ng Palmitoyl Tetrapeptide-7 Palmitoyl Hexapeptide-12 Sodium Hyaluronate Dipotassium Glycyrrhizate Glycyrrhiza Glabra Root Extract Avena Sativa Kernel Extract Arctium Lappa Seed Oil Salix Alba Extract Glycine Soja Sterols Lecithin Allantoin Tocopheryl Acetate Hydrolyzed Soy Protein Sorbitan Laurate Acetyl Dipeptide-1 Cetyl Ester Disodium EDTA Hydroxyethylcellulose Palmitoyl Tripeptide-1 Sodium Hydroxide Tribehenin Caprylyl Glycol Ethylhexylglycerin Pentylene Glycol PEG-75 Shea Butter Glycerides PPG-12/Smdi Copolymer PEG-10 Phytosterol PEG-8 Dimethicone PEG-14 Magnesium Aluminum Silicate Arachidyl Glucoside Arachidyl Alcohol Sclerotium Gum Carbomer Benzoic Acid Water, Dimethicone, Glycerin, Butylene Glycol, Isononyl Isononanoate, Castor Isostearate Succinate, Glyceryl Steara These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane. What it does: Dimethicone comes in different viscosities: Depending on the viscosity, dimethicone has different properties. Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity. This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient. Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy. Dimethicone Crosspolymer is a silicone created by modifying dimethicone with hydrocarbon side chains. Due to its large size, it does not penetrate skin. It is considered non-occlusive. Dimethicone Crosspolymer is used to stabilize and thicken products. It also helps give products a silky feel. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Isononyl Isononanoate is a synthetic skin-conditioner and texture enhancer. It is created from nonanoic acid, a fatty acid found in cocoa and lavender oil. As an emollient, Isononyl Isononanoate helps keep your skin soft and smooth. This is because emollients create a barrier on the skin to trap moisture in. Isononyl Isononanoate helps give products a velvet feel and improves spreadability. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longe