La Mer The Lifting Contour Serum Versus SkinCeuticals P-Tiox Wrinkle Modulating Peptide Serum

La Mer The Lifting Contour Serum Versus SkinCeuticals P-Tiox Wrinkle Modulating Peptide Serum Detailed comparison of La Mer The Lifting Contour Serum versus SkinCeuticals P-Tiox Wrinkle Modulating Peptide Serum. This anti-aging serum is formulated around Acetyl Hexapeptide-8 to soften the look of wrinkles. This anti-aging serum is formulated around Dipeptide Diaminobutyroyl Benzylamide Diacetate and Acetyl Hexapeptide-8 to soften the look of wrinkles and refine skin texture. Butylene Glycol Methyl Gluceth-20 PEG-75 Alcohol Denat. Bis-PEG-18 Methyl Ether Dimethyl Silane Algae Extract Sesamum Indicum Seed Oil Medicago Sativa Seed Powder Helianthus Annuus Seedcake Prunus Amygdalus Dulcis Seed Meal Eucalyptus Globulus Leaf Oil Sodium Gluconate Copper Gluconate Calcium Gluconate Magnesium Gluconate Zinc Gluconate Tocopheryl Succinate Niacin Sesamum Indicum Seed Powder Bupleurum Falcatum Root Extract Sigesbeckia Orientalis Extract Lens Esculenta Fruit Extract Pyrus Malus Fruit Extract Citrullus Lanatus Fruit Extract Faex Extract Polygonum Cuspidatum Root Extract Helichrysum Arenarium Extract Ascophyllum Nodosum Extract Vitis Vinifera Seed Extract Humulus Lupulus Extract Palmaria Palmata Extract Citrus Reticulata Peel Extract Asparagopsis Armata Extract Chlorella Vulgaris Extract Coriandrum Sativum Seed Oil Glycerin Oleth-5 Citrus Grandis Peel Oil Laminaria Saccharina Extract Punica Granatum Fruit Juice Glycereth-26 Saccharomyces Lysate Extract Crithmum Maritimum Extract Laminaria Digitata Extract Bifida Ferment Lysate PEG-8 Squalane Linoleic Acid Hydrogenated Lecithin Micrococcus Lysate Oleth-10 Phosphate Sorbitol Caprylyl Glycol Ethylbisiminomethylguaiacol Manganese Chloride Tourmaline Sucrose Caffeine Lecithin Coenzyme A Acetyl Glucosamine Linolenic Acid Acetyl Hexapeptide-8 Styrene/Vp Copolymer Magnesium Ascorbyl Phosphate Tetraacetylphytosphingosine Methyldihydrojasmonate Choleth-24 Dipotassium Glycyrrhizate Ceteth-24 Sodium Hyaluronate Hexylene Glycol Hydrolyzed Jojoba Esters Sodium Benzoate Sodium Lactate Hydrogenated Vegetable Oil Potassium Sorbate Lavandula Angustifolia Oil Rosmarinus Officinalis Leaf Extract Octadecenedioic Acid Carbomer Sodium PCA Nordihydroguaiaretic Acid Ergothioneine Sodium Hydroxide Xanthan Gum Caprylic/Capric Triglyceride Disodium EDTA BHT Phenoxyethanol Linalyl Acetate Linalool Limonene CI 14700 CI 19140 CI 17200 Butylene Glycol, Methyl Gluceth-20, PEG-75, Alcohol Denat., Bis-PEG-18 Methyl Ether Dimethyl Silane, Algae Extract, Sesamum Indicum Seed Oil, Medicago Sativa Seed Powder, Helianthus Annuus Seedcake, Prunus Amygdalus Dulcis Seed Meal, Eucalyptus Globulus Leaf Oil, Sodium Gluconate, Copper Gluconate, Calcium Gluconate, Magnesium Gluconate, Zinc Gluconate, Tocopheryl Succinate, Niacin, Sesamum Indicum Seed Powder, Bupleurum Falcatum Root Extract, Sigesbeckia Orientalis Extract, Lens Esculenta Fruit Extract, Pyrus Malus Fruit Extract, Citrullus Lanatus Fruit Extract, Faex Extract, Polygonum Cuspidatum Root Extract, Helichrysum Arenarium Extract, Ascophyllum Nodosum Extract, Vitis Vinifera Seed Extract, Humulus Lupulus Extract, Palmaria Palmata Extract, Citrus Reticulata Peel Extract, Asparagopsis Armata Extract, Chlorella Vulgaris Extract, Coriandrum Sativum Seed Oil, Glycerin, Oleth-5, Citrus Grandis Peel Oil, Laminaria Saccharina Extract, Punica Granatum Fruit Juice, Glycereth-26, Saccharomyces Lysate Extract, Crithmum Maritimum Extract, Laminaria Digitata Extract, Bifida Ferment Lys Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. Alcohol Denat. is an alcohol with a denaturant property. It is created by mixing ethanol with other additives. The "denat" part just means "denatured"; common denaturants include Denatonium Benzoate, t-butyl alcohol, and Diethyl Phthalate. This step makes the alcohol undrinkable (and lets brand skip taxes related to beverage alcohol). This ingredient gets a bad rep because it is irritating and drying due to its astringent property. Astringents draw out natural oils in tissue to constrict pores and dry out your skin. However, alcohol denat. is not all that bad. Due to its low molecular weight, alcohol denat. tends to evaporate quickly. One study on pig skin found half of applied alcohol evaporated in 10 seconds and less than 3% stayed on skin. This also helps other ingredients become better absorbed upon application. Studies are conflicted about whether this ingredient causes skin dehydration. One study from 2005 found adding emollients to propanol-based sanitizer decreased skin dryness and irritation. Another study found irritation only occurs if your skin is already damaged. Small amounts of alcohol are generally tolerated by oily skin or people who live in humid environments. The rule of thumb is this ingredient will probably not affect your skin much if it is near the end of an ingredients list. One thing to note: People with ALDH2 (aldehyde dehydrogenase 2) deficiency may experience skin irritation from continued alcohol use. About 8% of the world's population have this deficiency. The Cosmetic Ingredient Review Expert Panel has determined denatured alcohols to be safe for use in concentrations between 0.05% and 12% (depending on which denaturant is used). Also... This in