Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

La Mer The Moisturizing Soft Cream Versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer

La Mer The Moisturizing Soft Cream Versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer Detailed comparison of La Mer The Moisturizing Soft Cream versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer. This barrier-repair moisturizer is formula

This source-based comparison does not add ratings or recommend a winner.

La Mer The Moisturizing Soft Cream Versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer Detailed comparison of La Mer The Moisturizing Soft Cream versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer. This barrier-repair moisturizer is formulated around Petrolatum and Cholesterol to strengthen the skin barrier and hydrate skin. This anti-aging night moisturizer is formulated around Retinol and Niacinamide to soften the look of wrinkles and refine skin texture. Algae Extract Cyclopentasiloxane Petrolatum Glyceryl Distearate Phenyl Trimethicone Cyclohexasiloxane Butylene Glycol Cholesterol Butyrospermum Parkii Butter Steareth-10 Dimethicone Glyceryl Stearate Se Polysilicone-11 Glyceryl Triacetyl Ricinoleate Macadamia Integrifolia Seed Oil Glycerin Sesamum Indicum Seed Oil Medicago Sativa Seed Powder Helianthus Annuus Seedcake Prunus Amygdalus Dulcis Seed Meal Eucalyptus Globulus Leaf Oil Sodium Gluconate Copper Gluconate Calcium Gluconate Magnesium Gluconate Zinc Gluconate Tocopheryl Succinate Niacin Sesamum Indicum Seed Powder Water Citrus Aurantifolia Peel Extract Laminaria Digitata Extract Crithmum Maritimum Extract Salicornia Herbacea Extract Plankton Extract Chlorella Vulgaris Extract Rosmarinus Officinalis Leaf Extract Sodium Hyaluronate Tocopheryl Acetate Acetyl Hexapeptide-8 Caffeine Tetrahexyldecyl Ascorbate Palmitoyl Hexapeptide-12 Caprylic/Capric Triglyceride Triethylhexanoin Sodium PCA Cetyl Alcohol Diethylhexyl Succinate Isocetyl Stearoyl Stearate Cyanocobalamin C13-14 Isoparaffin Distearyldimonium Chloride Dipalmitoyl Hydroxyproline Sucrose Hydrogenated Vegetable Oil Trehalose Hydrolyzed Algin Micrococcus Lysate Maris Sal Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate Lactoperoxidase Glucose Oxidase Urea Glucose Polyacrylamide Glyceryl Polymethacrylate PEG-8 Laureth-7 Lecithin Triacetin Sodium Chloride Polyquaternium-51 Potassium Phosphate Alcohol Denat. Parfum Limonene Linalool Hydroxycitronellal Citronellol Geraniol BHT Disodium EDTA Sorbic Acid Chlorphenesin Potassium Sorbate Phenoxyethanol Algae Extract, Cyclopentasiloxane, Petrolatum, Glyceryl Distearate, Phenyl Trimethicone, Cyclohexasiloxane, Butylene Glycol, Cholesterol, Butyrospermum Parkii Butter, Steareth-10, Dimethicone, Glyceryl Stearate Se, Polysilicone-11, Glyceryl Triacetyl Ricinoleate, Macadamia Integrifolia Seed Oil, Glycerin, Sesamum Indicum Seed Oil, Medicago Sativa Seed Powder, Helianthus Annuus Seedcake, Prunus Amygdalus Dulcis Seed Meal, Eucalyptus Globulus Leaf Oil, Sodium Gluconate, Copper Gluconate, Calcium Gluconate, Magnesium Gluconate, Zinc Gluconate, Tocopheryl Succinate, Niacin, Sesamum Indicum Seed Powder, Water, Citrus Aurantifolia Peel Extract, Laminaria Digitata Extract, Crithmum Maritimum Extract, Salicornia Herbacea Extract, Plankton Extract, Chlorella Vulgaris Extract, Rosmarinus Officinalis Leaf Extract, Sodium Hyaluronate, Tocopheryl Acetate, Acetyl Hexapeptide-8, Caffeine, Tetrahexyldecyl Ascorbate, Palmitoyl Hexapeptide-12, Caprylic/Capric Triglyceride, Triethylhexanoin, Sodium PCA, Cetyl Alcohol, Diethylhexyl Succinate, Isocetyl Stearoyl Stearate, Cyanocobalamin, C13-14 Isoparaffin, Distearyldimonium Chloride, Dipalmitoyl Hydroxyproline, Sucrose, Hydrogenated Vegetable Oil, Trehalose, Hydrolyzed Algin, Micrococcus Lysate, Maris Sal, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Lactoperoxidase, Glucose Oxidase, Urea, Glucose, Polyacrylamide, Glyceryl Polymethacry These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. C13-14 Isoparaffin is a synthetic emollient, solvent, and thickening agent. It helps soften skin and improves spreadability without leaving a greasy residue. This ingredient has been found to be non-sensitizing and safe for use in cosmetics. Two things floating around online that cause fear-mongering: There's one scary-sounding study related to kidney tumors in male rats; this depends on a protein called alpha-2u-globulin that binds the ingredient and clogs up kidney cells. Female rats barely make this protein, and humans don't make it at all so this effect cannot happen to us. Regulatory bodies have states this rat-only pathway shouldn't be used to judge human risk. The other thing you'll see is 1,4-dioxane being a trace byproduct that can form during manufacturing of petroleum-derived ingredients. This is a real, but heavily managed/monitored issue. This byproduct is removed through purification steps before the ingredients goes into the formula. Regulatory bodies also actively monitor residual levels for safety. One last thing to note: this ingredient is a pure hydrocarbon with no fatty-acid or ester chains for Malassezia to feed on, so it's considered fungal acne safe. Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss. Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid. In practice, that translates to a long shelf life and a consistently elegant skin feel. While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns. Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source. This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out. This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%. Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane. What it does: Dimethicone comes in different viscosities: Depending on the viscosity, dimethicone has different properties. Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions